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160 related items for PubMed ID: 2869965

  • 1. Overproduction of the first three enzymes of pyrimidine nucleotide biosynthesis in Drosophila cells resistant to N-phosphonacetyl-L-aspartate.
    Laval M, Azou Y, Giorgi D, Rosset R.
    Exp Cell Res; 1986 Apr; 163(2):381-95. PubMed ID: 2869965
    [Abstract] [Full Text] [Related]

  • 2. Stable mutants of mammalian cells that overproduce the first three enzymes of pyrimidine nucleotide biosynthesis.
    Kempe TD, Swyryd EA, Bruist M, Stark GR.
    Cell; 1976 Dec; 9(4 Pt 1):541-50. PubMed ID: 12870
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  • 3. N-(Phosphonacetyl)-L-aspartate inhibition of the enzyme complex of pyrimidine biosynthesis.
    Moore EC.
    Biochem Pharmacol; 1982 Oct 15; 31(20):3313-6. PubMed ID: 7150357
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  • 4. Aspartate carbamoyltransferase activity, drug concentrations, and pyrimidine nucleotides in tissue from patients treated with N-(phosphonacetyl)-L-aspartate.
    Moore EC, Friedman J, Valdivieso M, Plunkett W, Marti JR, Russ J, Loo TL.
    Biochem Pharmacol; 1982 Oct 15; 31(20):3317-21. PubMed ID: 7150358
    [Abstract] [Full Text] [Related]

  • 5. Properties of single-step mutants of Syrian hamster cell lines resistant to N-(phosphonacetyl)-L-aspartate.
    Zieg J, Clayton CE, Ardeshir F, Giulotto E, Swyryd EA, Stark GR.
    Mol Cell Biol; 1983 Nov 15; 3(11):2089-98. PubMed ID: 6656764
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  • 6. Multiple mechanisms of N-phosphonacetyl-L-aspartate resistance in human cell lines: carbamyl-P synthetase/aspartate transcarbamylase/dihydro-orotase gene amplification is frequent only when chromosome 2 is rearranged.
    Smith KA, Chernova OB, Groves RP, Stark MB, Martínez JL, Davidson JN, Trent JM, Patterson TE, Agarwal A, Duncan P, Agarwal ML, Stark GR.
    Proc Natl Acad Sci U S A; 1997 Mar 04; 94(5):1816-21. PubMed ID: 9050862
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  • 7. Overexpression of the 18 kDa and 22/24 kDa FGF-2 isoforms results in differential drug resistance and amplification potential.
    Dini G, Funghini S, Witort E, Magnelli L, Fanti E, Rifkin DB, Del Rosso M.
    J Cell Physiol; 2002 Oct 04; 193(1):64-72. PubMed ID: 12209881
    [Abstract] [Full Text] [Related]

  • 8. Effects of acivicin and PALA, singly and in combination, on de novo pyrimidine biosynthesis.
    Kensler TW, Jayaram HN, Cooney DA.
    Adv Enzyme Regul; 1982 Oct 04; 20():57-73. PubMed ID: 7113804
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  • 9. Flux through the de novo pyrimidine pathway in vivo. Effect of N-phosphonacetyl-L-aspartate, a potent inhibitor of aspartate transcarbamylase.
    Monks A, Anderson LW, Strong J, Cysyk RL.
    J Biol Chem; 1983 Nov 25; 258(22):13564-9. PubMed ID: 6417130
    [Abstract] [Full Text] [Related]

  • 10. Aspartate transcarbamylase from Leishmania donovani. A discrete, nonregulatory enzyme as a potential chemotherapeutic site.
    Mukherjee T, Ray M, Bhaduri A.
    J Biol Chem; 1988 Jan 15; 263(2):708-13. PubMed ID: 2891701
    [Abstract] [Full Text] [Related]

  • 11. Uracil nucleotide synthesis in a human breast cancer cell line (MCF-7) and in two drug-resistant sublines that contain increased levels of enzymes of the de novo pyrimidine pathway.
    Karle JM, Cowan KH, Chisena CA, Cysyk RL.
    Mol Pharmacol; 1986 Aug 15; 30(2):136-41. PubMed ID: 2874477
    [Abstract] [Full Text] [Related]

  • 12. Co-amplification of rRNA genes with CAD genes in N-(phosphonacetyl)-L-aspartate-resistant Syrian hamster cells.
    Wahl GM, Vitto L, Rubnitz J.
    Mol Cell Biol; 1983 Nov 15; 3(11):2066-75. PubMed ID: 6318080
    [Abstract] [Full Text] [Related]

  • 13. Late onset of CAD gene amplification in unamplified PALA resistant Chinese hamster mutants.
    Mucciolo E, Bertoni L, Mondello C, Giulotto E.
    Cancer Lett; 2000 Mar 31; 150(2):119-27. PubMed ID: 10704733
    [Abstract] [Full Text] [Related]

  • 14. Induction of CAD gene amplification by restriction endonucleases in V79,B7 Chinese hamster cells.
    Cavolina P, Agnese C, Maddalena A, Sciandrello G, Di Leonardo A.
    Mutat Res; 1989 Mar 31; 225(1-2):61-4. PubMed ID: 2563307
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