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Journal Abstract Search

245 related items for PubMed ID: 2870801

  • 1. Covalent binding of 1,2-dihaloalkanes to DNA and stability of the major DNA adduct, S-[2-(N7-guanyl)ethyl]glutathione.
    Inskeep PB, Koga N, Cmarik JL, Guengerich FP.
    Cancer Res; 1986 Jun; 46(6):2839-44. PubMed ID: 2870801
    [Abstract] [Full Text] [Related]

  • 2. Selectivity of rat and human glutathione S-transferases in activation of ethylene dibromide by glutathione conjugation and DNA binding and induction of unscheduled DNA synthesis in human hepatocytes.
    Cmarik JL, Inskeep PB, Meredith MJ, Meyer DJ, Ketterer B, Guengerich FP.
    Cancer Res; 1990 May 01; 50(9):2747-52. PubMed ID: 2328501
    [Abstract] [Full Text] [Related]

  • 3. Synthesis of oligonucleotides containing the ethylene dibromide-derived DNA adducts S-[2-(N7-guanyl)ethyl]glutathione, S-[2-(N2-guanyl)ethyl]glutathione, and S-[2-(O6-guanyl)ethyl]glutathione at a single site.
    Kim MS, Guengerich FP.
    Chem Res Toxicol; 1997 Oct 01; 10(10):1133-43. PubMed ID: 9348436
    [Abstract] [Full Text] [Related]

  • 4. Excretion of the mercapturic acid S-[2-(N7-guanyl)ethyl]-N-acetylcysteine in urine following administration of ethylene dibromide to rats.
    Kim DH, Guengerich FP.
    Cancer Res; 1989 Nov 01; 49(21):5843-7. PubMed ID: 2790795
    [Abstract] [Full Text] [Related]

  • 5. Polymerase blockage and misincorporation of dNTPs opposite the ethylene dibromide-derived DNA adducts S-[2-(N7-guanyl)ethyl]glutathione, S-[2-(N2-guanyl)ethyl]glutathione, and S-[2-(O6-guanyl)ethyl]glutathione.
    Kim MS, Guengerich FP.
    Chem Res Toxicol; 1998 Apr 01; 11(4):311-6. PubMed ID: 9548801
    [Abstract] [Full Text] [Related]

  • 6. Activation of dihaloalkanes by glutathione conjugation and formation of DNA adducts.
    Guengerich FP, Peterson LA, Cmarik JL, Koga N, Inskeep PB.
    Environ Health Perspect; 1987 Dec 01; 76():15-8. PubMed ID: 3329096
    [Abstract] [Full Text] [Related]

  • 7. DNA-glutathione adducts derived from vic-dihaloalkanes: mechanisms of mutagenesis.
    Guengerich FP, Humphreys WG, Kim DH, Oida T, Cmarik JL.
    Princess Takamatsu Symp; 1990 Dec 01; 21():101-7. PubMed ID: 2134669
    [Abstract] [Full Text] [Related]

  • 8. Formation of the DNA adduct S-[2-(N7-guanyl)ethyl]glutathione from ethylene dibromide: effects of modulation of glutathione and glutathione S-transferase levels and lack of a role for sulfation.
    Kim DH, Guengerich FP.
    Carcinogenesis; 1990 Mar 01; 11(3):419-24. PubMed ID: 2311185
    [Abstract] [Full Text] [Related]

  • 9. S-[2-(N7-guanyl)ethyl]glutathione, the major DNA adduct formed from 1,2-dibromoethane.
    Koga N, Inskeep PB, Harris TM, Guengerich FP.
    Biochemistry; 1986 Apr 22; 25(8):2192-8. PubMed ID: 3707941
    [Abstract] [Full Text] [Related]

  • 10. Evidence for formation of an S-[2-(N7-guanyl)ethyl]glutathione adduct in glutathione-mediated binding of the carcinogen 1,2-dibromoethane to DNA.
    Ozawa N, Guengerich FP.
    Proc Natl Acad Sci U S A; 1983 Sep 22; 80(17):5266-70. PubMed ID: 6577422
    [Abstract] [Full Text] [Related]

  • 11. Analysis of DNA adducts formed in vivo in rats and mice from 1,2-dibromoethane, 1,2-dichloroethane, dibromomethane, and dichloromethane using HPLC/accelerator mass spectrometry and relevance to risk estimates.
    Watanabe K, Liberman RG, Skipper PL, Tannenbaum SR, Guengerich FP.
    Chem Res Toxicol; 2007 Nov 22; 20(11):1594-600. PubMed ID: 17907789
    [Abstract] [Full Text] [Related]

  • 12. Analysis of DNA adduct, S-[2-(N7-guanyl)ethyl]glutathione, by liquid chromatography/mass spectrometry and liquid chromatography/tandem mass spectrometry.
    Huang H, Jemal A, David C, Barker SA, Swenson DH, Means JC.
    Anal Biochem; 1998 Dec 01; 265(1):139-50. PubMed ID: 9866718
    [Abstract] [Full Text] [Related]

  • 13. Characterization of S-[2-(N1-adenyl)ethyl]glutathione as an adduct formed in RNA and DNA from 1,2-dibromoethane.
    Kim DH, Humphreys WG, Guengerich FP.
    Chem Res Toxicol; 1990 Dec 01; 3(6):587-94. PubMed ID: 1715767
    [Abstract] [Full Text] [Related]

  • 14. Mutation spectrum and sequence alkylation selectivity resulting from modification of bacteriophage M13mp18 DNA with S-(2-chloroethyl)glutathione. Evidence for a role of S-(2-N7-guanyl)ethyl)glutathione as a mutagenic lesion formed from ethylene dibromide.
    Cmarik JL, Humphreys WG, Bruner KL, Lloyd RS, Tibbetts C, Guengerich FP.
    J Biol Chem; 1992 Apr 05; 267(10):6672-9. PubMed ID: 1551876
    [Abstract] [Full Text] [Related]

  • 15. In vitro biotransformation and genotoxicity of the drinking water disinfection byproduct bromodichloromethane: DNA binding mediated by glutathione transferase theta 1-1.
    Ross MK, Pegram RA.
    Toxicol Appl Pharmacol; 2004 Mar 01; 195(2):166-81. PubMed ID: 14998683
    [Abstract] [Full Text] [Related]

  • 16. In vitro metabolism of 1,2-dihaloethanes to ethylene.
    Livesey JC, Anders MW.
    Drug Metab Dispos; 1979 Mar 01; 7(4):199-203. PubMed ID: 39719
    [Abstract] [Full Text] [Related]

  • 17. Binding of carcinogenic halogenated hydrocarbons to cell macromolecules.
    Banerjee S, Van Duuren BL.
    J Natl Cancer Inst; 1979 Sep 01; 63(3):707-11. PubMed ID: 381753
    [Abstract] [Full Text] [Related]

  • 18. Isolation and characterization of N7-guanyl adducts derived from 1,2-dibromo-3-chloropropane.
    Humphreys WG, Kim DH, Guengerich FP.
    Chem Res Toxicol; 1991 Sep 01; 4(4):445-53. PubMed ID: 1912332
    [Abstract] [Full Text] [Related]

  • 19. NTP technical report on the toxicity and metabolism studies of chloral hydrate (CAS No. 302-17-0). Administered by gavage to F344/N rats and B6C3F1 mice.
    Beland FA.
    Toxic Rep Ser; 1999 Aug 01; (59):1-66, A1-E7. PubMed ID: 11803702
    [Abstract] [Full Text] [Related]

  • 20. Glutathione-mediated binding of dibromoalkanes to DNA: specificity of rat glutathione-S-transferases and dibromoalkane structure.
    Inskeep PB, Guengerich FP.
    Carcinogenesis; 1984 Jun 01; 5(6):805-8. PubMed ID: 6373044
    [Abstract] [Full Text] [Related]

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