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Journal Abstract Search

232 related items for PubMed ID: 28719882

  • 1. Antileishmanial activity and tubulin polymerization inhibition of podophyllotoxin derivatives on Leishmania infantum.
    Escudero-Martínez JM, Pérez-Pertejo Y, Reguera RM, Castro MÁ, Rojo MV, Santiago C, Abad A, García PA, López-Pérez JL, San Feliciano A, Balaña-Fouce R.
    Int J Parasitol Drugs Drug Resist; 2017 Dec; 7(3):272-285. PubMed ID: 28719882
    [Abstract] [Full Text] [Related]

  • 2. Antileishmanial activity of terpenylquinones on Leishmania infantum and their effects on Leishmania topoisomerase IB.
    Pérez-Pertejo Y, Escudero-Martínez JM, Reguera RM, Balaña-Fouce R, García PA, Jambrina PG, San Feliciano A, Castro MÁ.
    Int J Parasitol Drugs Drug Resist; 2019 Dec; 11():70-79. PubMed ID: 31678841
    [Abstract] [Full Text] [Related]

  • 3. Synthesis and biological evaluation of podophyllotoxin congeners as tubulin polymerization inhibitors.
    Kamal A, Srinivasa Reddy T, Polepalli S, Shalini N, Reddy VG, Subba Rao AV, Jain N, Shankaraiah N.
    Bioorg Med Chem; 2014 Oct 01; 22(19):5466-75. PubMed ID: 25131956
    [Abstract] [Full Text] [Related]

  • 4. A Novel Cytotoxic Conjugate Derived from the Natural Product Podophyllotoxin as a Direct-Target Protein Dual Inhibitor.
    Hernández ÁP, Díez P, García PA, Pérez-Andrés M, Ortega P, Jambrina PG, Díez D, Castro MÁ, Fuentes M.
    Molecules; 2020 Sep 17; 25(18):. PubMed ID: 32957517
    [Abstract] [Full Text] [Related]

  • 5. Structural and Biochemical Characterization of the Interaction of Tubulin with Potent Natural Analogues of Podophyllotoxin.
    Antúnez-Mojica M, Rodríguez-Salarichs J, Redondo-Horcajo M, León A, Barasoain I, Canales Á, Cañada FJ, Jiménez-Barbero J, Alvarez L, Díaz JF.
    J Nat Prod; 2016 Aug 26; 79(8):2113-21. PubMed ID: 27518758
    [Abstract] [Full Text] [Related]

  • 6. Identification of potent virtual leads and ADME prediction of isoxazolidine podophyllotoxin derivatives as topoisomerase II and tubulin inhibitors.
    Bkhaitan MM, Mirza AZ, Shamshad H, Ali HI.
    J Mol Graph Model; 2017 May 26; 73():74-93. PubMed ID: 28242581
    [Abstract] [Full Text] [Related]

  • 7. Substituted 1,5-naphthyridine derivatives as novel antileishmanial agents. Synthesis and biological evaluation.
    Tejería A, Pérez-Pertejo Y, Reguera RM, Balaña-Fouce R, Alonso C, González M, Rubiales G, Palacios F.
    Eur J Med Chem; 2018 May 25; 152():137-147. PubMed ID: 29704722
    [Abstract] [Full Text] [Related]

  • 8. Biological evaluation and molecular modelling study of podophyllotoxin derivatives as potent inhibitors of tubulin polymerization.
    Ma Y, Fang S, Li H, Han C, Lu Y, Zhao Y, Liu Y, Zhao C.
    Chem Biol Drug Des; 2013 Jul 25; 82(1):12-21. PubMed ID: 23786349
    [Abstract] [Full Text] [Related]

  • 9. In vivo antileishmanial activity and histopathological evaluation in Leishmania infantum infected hamsters after treatment with a furoxan derivative.
    de Almeida L, Passalacqua TG, Dutra LA, Fonseca JNVD, Nascimento RFQ, Imamura KB, de Andrade CR, Dos Santos JL, Graminha MAS.
    Biomed Pharmacother; 2017 Nov 25; 95():536-547. PubMed ID: 28866421
    [Abstract] [Full Text] [Related]

  • 10. Synthesis and biological evaluation of a series of podophyllotoxins derivatives as a class of potent antitubulin agents.
    Liu Y, Wei D, Zhao Y, Cheng W, Lu Y, Ma Y, Li X, Han C, Wei Y, Cao H, Zhao C.
    Bioorg Med Chem; 2012 Nov 01; 20(21):6285-95. PubMed ID: 23022053
    [Abstract] [Full Text] [Related]

  • 11. Antileishmanial effect of new indeno-1,5-naphthyridines, selective inhibitors of Leishmania infantum type IB DNA topoisomerase.
    Tejería A, Pérez-Pertejo Y, Reguera RM, Balaña-Fouce R, Alonso C, Fuertes M, González M, Rubiales G, Palacios F.
    Eur J Med Chem; 2016 Nov 29; 124():740-749. PubMed ID: 27639365
    [Abstract] [Full Text] [Related]

  • 12. Investigation of podophyllotoxin esters as potential anticancer agents: synthesis, biological studies and tubulin inhibition properties.
    Shareef MA, Duscharla D, Ramasatyaveni G, Dhoke NR, Das A, Ummanni R, Srivastava AK.
    Eur J Med Chem; 2015 Jan 07; 89():128-37. PubMed ID: 25462233
    [Abstract] [Full Text] [Related]

  • 13. Gimatecan and other camptothecin derivatives poison Leishmania DNA-topoisomerase IB leading to a strong leishmanicidal effect.
    Prada CF, Alvarez-Velilla R, Balaña-Fouce R, Prieto C, Calvo-Álvarez E, Escudero-Martínez JM, Requena JM, Ordóñez C, Desideri A, Pérez-Pertejo Y, Reguera RM.
    Biochem Pharmacol; 2013 May 15; 85(10):1433-40. PubMed ID: 23466420
    [Abstract] [Full Text] [Related]

  • 14. Podophyllotoxin derivatives-tubulin complex reveals a potential binding site of tubulin polymerization inhibitors in α-tubulin adjacent to colchicine site.
    Zhao W, Shen R, Li HM, Zhong JJ, Tang YJ.
    Int J Biol Macromol; 2024 Sep 15; 276(Pt 1):133678. PubMed ID: 38971286
    [Abstract] [Full Text] [Related]

  • 15. Cytotoxic Cyclolignans Obtained by the Enlargement of the Cyclolignan Skeleton of Podophyllic Aldehyde, a Selective Podophyllotoxin-Derived Cyclolignan.
    García PA, Hernández ÁP, Gómez-Zurita MA, Miguel Del Corral JM, Gordaliza M, Francesch A, San Feliciano A, Castro MÁ.
    Molecules; 2024 Mar 23; 29(7):. PubMed ID: 38611722
    [Abstract] [Full Text] [Related]

  • 16. Podophyllic Aldehyde, a Podophyllotoxin Derivate, Elicits Different Cell Cycle Profiles Depending on the Tumor Cell Line: A Systematic Proteomic Analysis.
    Hernández ÁP, Chaparro-González L, Garzo-Sánchez O, Arias-Hidalgo C, Juanes-Velasco P, García PA, Castro MÁ, Fuentes M.
    Int J Mol Sci; 2024 Apr 24; 25(9):. PubMed ID: 38731850
    [Abstract] [Full Text] [Related]

  • 17. Structure of 4'-demethylepipodophyllotoxin in complex with tubulin provides a rationale for drug design.
    Niu L, Wang Y, Wang C, Wang Y, Jiang X, Ma L, Wu C, Yu Y, Chen Q.
    Biochem Biophys Res Commun; 2017 Nov 04; 493(1):718-722. PubMed ID: 28864414
    [Abstract] [Full Text] [Related]

  • 18. Synthesis and antimitotic and tubulin interaction profiles of novel pinacol derivatives of podophyllotoxins.
    Abad A, López-Pérez JL, del Olmo E, García-Fernández LF, Francesch A, Trigili C, Barasoain I, Andreu JM, Díaz JF, San Feliciano A.
    J Med Chem; 2012 Aug 09; 55(15):6724-37. PubMed ID: 22607205
    [Abstract] [Full Text] [Related]

  • 19. Antitumor agents. I. DNA topoisomerase II inhibitory activity and the structural relationship of podophyllotoxin derivatives as antitumor agents.
    Terada T, Fujimoto K, Nomura M, Yamashita J, Kobunai T, Takeda S, Wierzba K, Yamada Y, Yamaguchi H.
    Chem Pharm Bull (Tokyo); 1992 Oct 09; 40(10):2720-7. PubMed ID: 1334447
    [Abstract] [Full Text] [Related]

  • 20. Morpholino derivatives of benzyl-benzodioxole, a study of structural requirements for drug interactions at the colchicine/podophyllotoxin binding site of tubulin.
    Batra JK, Jurd L, Hamel E.
    Biochem Pharmacol; 1986 Nov 15; 35(22):4013-8. PubMed ID: 3778522
    [Abstract] [Full Text] [Related]

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