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Journal Abstract Search

346 related items for PubMed ID: 28726778

  • 1. Protection of Mcc950 against high-glucose-induced human retinal endothelial cell dysfunction.
    Zhang Y, Lv X, Hu Z, Ye X, Zheng X, Ding Y, Xie P, Liu Q.
    Cell Death Dis; 2017 Jul 20; 8(7):e2941. PubMed ID: 28726778
    [Abstract] [Full Text] [Related]

  • 2. Inhibiting the NLRP3 inflammasome with MCC950 ameliorates retinal neovascularization and leakage by reversing the IL-1β/IL-18 activation pattern in an oxygen-induced ischemic retinopathy mouse model.
    Sui A, Chen X, Shen J, Demetriades AM, Yao Y, Yao Y, Zhu Y, Shen X, Xie B.
    Cell Death Dis; 2020 Oct 22; 11(10):901. PubMed ID: 33093455
    [Abstract] [Full Text] [Related]

  • 3. Inhibition of NLRP3 inflammasome by MCC950 improves the metabolic outcome of islet transplantation by suppressing IL-1β and islet cellular death.
    Matsuoka T, Yoshimatsu G, Sakata N, Kawakami R, Tanaka T, Yamada T, Yoshida Y, Hasegawa S, Kodama S.
    Sci Rep; 2020 Oct 21; 10(1):17920. PubMed ID: 33087823
    [Abstract] [Full Text] [Related]

  • 4. The effects of NLRP3 inflammasome inhibition by MCC950 on LPS-induced pancreatic adenocarcinoma inflammation.
    Yaw ACK, Chan EWL, Yap JKY, Mai CW.
    J Cancer Res Clin Oncol; 2020 Sep 21; 146(9):2219-2229. PubMed ID: 32507974
    [Abstract] [Full Text] [Related]

  • 5. Targeting the NLRP3 Inflammasome With Inhibitor MCC950 Prevents Aortic Aneurysms and Dissections in Mice.
    Ren P, Wu D, Appel R, Zhang L, Zhang C, Luo W, Robertson AAB, Cooper MA, Coselli JS, Milewicz DM, Shen YH, LeMaire SA.
    J Am Heart Assoc; 2020 Apr 07; 9(7):e014044. PubMed ID: 32223388
    [Abstract] [Full Text] [Related]

  • 6. Inhibition of NLRP3 inflammasome ameliorates podocyte damage by suppressing lipid accumulation in diabetic nephropathy.
    Wu M, Yang Z, Zhang C, Shi Y, Han W, Song S, Mu L, Du C, Shi Y.
    Metabolism; 2021 May 07; 118():154748. PubMed ID: 33675822
    [Abstract] [Full Text] [Related]

  • 7. Evidence against a role for NLRP3-driven islet inflammation in db/db mice.
    Kammoun HL, Allen TL, Henstridge DC, Barre S, Coll RC, Lancaster GI, Cron L, Reibe S, Chan JY, Bensellam M, Laybutt DR, Butler MS, Robertson AAB, O'Neill LA, Cooper MA, Febbraio MA.
    Mol Metab; 2018 Apr 07; 10():66-73. PubMed ID: 29478918
    [Abstract] [Full Text] [Related]

  • 8. The selective NLRP3 inflammasome inhibitor MCC950 alleviates cholestatic liver injury and fibrosis in mice.
    Qu J, Yuan Z, Wang G, Wang X, Li K.
    Int Immunopharmacol; 2019 May 07; 70():147-155. PubMed ID: 30802677
    [Abstract] [Full Text] [Related]

  • 9. The selective NLRP3-inflammasome inhibitor MCC950 reduces myocardial fibrosis and improves cardiac remodeling in a mouse model of myocardial infarction.
    Gao R, Shi H, Chang S, Gao Y, Li X, Lv C, Yang H, Xiang H, Yang J, Xu L, Tang Y.
    Int Immunopharmacol; 2019 Sep 07; 74():105575. PubMed ID: 31299609
    [Abstract] [Full Text] [Related]

  • 10. NLRP3 Inflammasome Inhibition by MCC950 Reduces Atherosclerotic Lesion Development in Apolipoprotein E-Deficient Mice-Brief Report.
    van der Heijden T, Kritikou E, Venema W, van Duijn J, van Santbrink PJ, Slütter B, Foks AC, Bot I, Kuiper J.
    Arterioscler Thromb Vasc Biol; 2017 Aug 07; 37(8):1457-1461. PubMed ID: 28596375
    [Abstract] [Full Text] [Related]

  • 11. NLRP3 inflammasome blockade reduces liver inflammation and fibrosis in experimental NASH in mice.
    Mridha AR, Wree A, Robertson AAB, Yeh MM, Johnson CD, Van Rooyen DM, Haczeyni F, Teoh NC, Savard C, Ioannou GN, Masters SL, Schroder K, Cooper MA, Feldstein AE, Farrell GC.
    J Hepatol; 2017 May 07; 66(5):1037-1046. PubMed ID: 28167322
    [Abstract] [Full Text] [Related]

  • 12. Propionibacterium acnes induces intervertebral disc degeneration by promoting nucleus pulposus cell pyroptosis via NLRP3-dependent pathway.
    He D, Zhou M, Bai Z, Wen Y, Shen J, Hu Z.
    Biochem Biophys Res Commun; 2020 Jun 04; 526(3):772-779. PubMed ID: 32265028
    [Abstract] [Full Text] [Related]

  • 13. Selective NLRP3 inflammasome inhibitor reduces neuroinflammation and improves long-term neurological outcomes in a murine model of traumatic brain injury.
    Xu X, Yin D, Ren H, Gao W, Li F, Sun D, Wu Y, Zhou S, Lyu L, Yang M, Xiong J, Han L, Jiang R, Zhang J.
    Neurobiol Dis; 2018 Sep 04; 117():15-27. PubMed ID: 29859317
    [Abstract] [Full Text] [Related]

  • 14. Target of MCC950 in Inhibition of NLRP3 Inflammasome Activation: a Literature Review.
    Wu D, Chen Y, Sun Y, Gao Q, Li H, Yang Z, Wang Y, Jiang X, Yu B.
    Inflammation; 2020 Feb 04; 43(1):17-23. PubMed ID: 31646445
    [Abstract] [Full Text] [Related]

  • 15. Activation of the TXNIP/NLRP3 inflammasome pathway contributes to inflammation in diabetic retinopathy: a novel inhibitory effect of minocycline.
    Chen W, Zhao M, Zhao S, Lu Q, Ni L, Zou C, Lu L, Xu X, Guan H, Zheng Z, Qiu Q.
    Inflamm Res; 2017 Feb 04; 66(2):157-166. PubMed ID: 27785530
    [Abstract] [Full Text] [Related]

  • 16. Ameliorative effect of selective NLRP3 inflammasome inhibitor MCC950 in an ovalbumin-induced allergic rhinitis murine model.
    Zhang W, Ba G, Tang R, Li M, Lin H.
    Int Immunopharmacol; 2020 Jun 04; 83():106394. PubMed ID: 32193102
    [Abstract] [Full Text] [Related]

  • 17. MCC950 blocks enhanced interleukin-1β production in patients with NLRP3 low penetrance variants.
    Schuh E, Groß CJ, Wagner D, Schlüter M, Groß O, Kümpfel T.
    Clin Immunol; 2019 Jun 04; 203():45-52. PubMed ID: 30974290
    [Abstract] [Full Text] [Related]

  • 18. The NLRP3 inflammasome modulates glycolysis by increasing PFKFB3 in an IL-1β-dependent manner in macrophages.
    Finucane OM, Sugrue J, Rubio-Araiz A, Guillot-Sestier MV, Lynch MA.
    Sci Rep; 2019 Mar 11; 9(1):4034. PubMed ID: 30858427
    [Abstract] [Full Text] [Related]

  • 19. Nlrp3 Inflammasome Inhibitor MCC950 Ameliorates Obliterative Bronchiolitis by Inhibiting Th1/Th17 Response and Promoting Treg Response After Orthotopic Tracheal Transplantation in Mice.
    Xu KY, Tong S, Wu CY, Ding XC, Chen JL, Ming Y, Wang SH.
    Transplantation; 2020 Jun 11; 104(6):e151-e163. PubMed ID: 32108749
    [Abstract] [Full Text] [Related]

  • 20. MCC950 Inhibits NLRP3 Inflammasome and Alleviates Axonal Injures in Early Stages of Diffuse Axonal Injury in Rats.
    Zhao J, Guo X, Wang B, Yang Z, Huang T, Guo D, Zhang M, Song J.
    Neurochem Res; 2020 Sep 11; 45(9):2020-2031. PubMed ID: 32474832
    [Abstract] [Full Text] [Related]

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