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357 related items for PubMed ID: 28735895

  • 1. A Phosphosite within the SH2 Domain of Lck Regulates Its Activation by CD45.
    Courtney AH, Amacher JF, Kadlecek TA, Mollenauer MN, Au-Yeung BB, Kuriyan J, Weiss A.
    Mol Cell; 2017 Aug 03; 67(3):498-511.e6. PubMed ID: 28735895
    [Abstract] [Full Text] [Related]

  • 2. Tyrosine 192 within the SH2 domain of the Src-protein tyrosine kinase p56Lck regulates T-cell activation independently of Lck/CD45 interactions.
    Kästle M, Merten C, Hartig R, Kaehne T, Liaunardy-Jopeace A, Woessner NM, Schamel WW, James J, Minguet S, Simeoni L, Schraven B.
    Cell Commun Signal; 2020 Nov 23; 18(1):183. PubMed ID: 33225946
    [Abstract] [Full Text] [Related]

  • 3. A weak Lck tail bite is necessary for Lck function in T cell antigen receptor signaling.
    Nika K, Tautz L, Arimura Y, Vang T, Williams S, Mustelin T.
    J Biol Chem; 2007 Dec 07; 282(49):36000-9. PubMed ID: 17897955
    [Abstract] [Full Text] [Related]

  • 4. The CD45 tyrosine phosphatase regulates CD3-induced signal transduction and T cell development in recombinase-deficient mice: restoration of pre-TCR function by active p56(lck).
    Pingel S, Baker M, Turner M, Holmes N, Alexander DR.
    Eur J Immunol; 1999 Aug 07; 29(8):2376-84. PubMed ID: 10458749
    [Abstract] [Full Text] [Related]

  • 5. Phosphatase CD45 both positively and negatively regulates T cell receptor phosphorylation in reconstituted membrane protein clusters.
    Furlan G, Minowa T, Hanagata N, Kataoka-Hamai C, Kaizuka Y.
    J Biol Chem; 2014 Oct 10; 289(41):28514-25. PubMed ID: 25128530
    [Abstract] [Full Text] [Related]

  • 6. Regulation of Lck and Fyn tyrosine kinase activities by transmembrane protein tyrosine phosphatase leukocyte common antigen-related molecule.
    Tsujikawa K, Ichijo T, Moriyama K, Tadotsu N, Sakamoto K, Sakane N, Fukada S, Furukawa T, Saito H, Yamamoto H.
    Mol Cancer Res; 2002 Dec 10; 1(2):155-63. PubMed ID: 12496362
    [Abstract] [Full Text] [Related]

  • 7. CD45 and RPTPalpha display different protein tyrosine phosphatase activities in T lymphocytes.
    Ng DH, Jabali MD, Maiti A, Borodchak P, Harder KW, Brocker T, Malissen B, Jirik FR, Johnson P.
    Biochem J; 1997 Nov 01; 327 ( Pt 3)(Pt 3):867-76. PubMed ID: 9581568
    [Abstract] [Full Text] [Related]

  • 8. CD45-Csk phosphatase-kinase titration uncouples basal and inducible T cell receptor signaling during thymic development.
    Zikherman J, Jenne C, Watson S, Doan K, Raschke W, Goodnow CC, Weiss A.
    Immunity; 2010 Mar 26; 32(3):342-54. PubMed ID: 20346773
    [Abstract] [Full Text] [Related]

  • 9. Expression of CD45 lacking the catalytic protein tyrosine phosphatase domain modulates Lck phosphorylation and T cell activation.
    Wang Y, Johnson P.
    J Biol Chem; 2005 Apr 08; 280(14):14318-24. PubMed ID: 15687496
    [Abstract] [Full Text] [Related]

  • 10. Regulation of T cell development by c-Cbl: essential role of Lck.
    Chiang YJ, Hodes RJ.
    Int Immunol; 2015 May 08; 27(5):245-51. PubMed ID: 25477210
    [Abstract] [Full Text] [Related]

  • 11. The pool of preactivated Lck in the initiation of T-cell signaling: a critical re-evaluation of the Lck standby model.
    Ballek O, Valečka J, Manning J, Filipp D.
    Immunol Cell Biol; 2015 Apr 08; 93(4):384-95. PubMed ID: 25420722
    [Abstract] [Full Text] [Related]

  • 12. Lipids Regulate Lck Protein Activity through Their Interactions with the Lck Src Homology 2 Domain.
    Sheng R, Jung DJ, Silkov A, Kim H, Singaram I, Wang ZG, Xin Y, Kim E, Park MJ, Thiagarajan-Rosenkranz P, Smrt S, Honig B, Baek K, Ryu S, Lorieau J, Kim YM, Cho W.
    J Biol Chem; 2016 Aug 19; 291(34):17639-50. PubMed ID: 27334919
    [Abstract] [Full Text] [Related]

  • 13. The kinase Itk and the adaptor TSAd change the specificity of the kinase Lck in T cells by promoting the phosphorylation of Tyr192.
    Granum S, Sundvold-Gjerstad V, Gopalakrishnan RP, Berge T, Koll L, Abrahamsen G, Sørlie M, Spurkland A.
    Sci Signal; 2014 Dec 09; 7(355):ra118. PubMed ID: 25492967
    [Abstract] [Full Text] [Related]

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  • 15. Src kinases central to T-cell receptor signaling regulate TLR-activated innate immune responses from human T cells.
    Sharma N, Akhade AS, Qadri A.
    Innate Immun; 2016 Apr 09; 22(3):238-44. PubMed ID: 26888964
    [Abstract] [Full Text] [Related]

  • 16. Type of PaperY192 within the SH2 Domain of Lck Regulates TCR Signaling Downstream of PLC-γ1 and Thymic Selection.
    Kästle M, Merten C, Hartig R, Plaza-Sirvent C, Schmitz I, Bommhardt U, Schraven B, Simeoni L.
    Int J Mol Sci; 2022 Jun 30; 23(13):. PubMed ID: 35806279
    [Abstract] [Full Text] [Related]

  • 17. Subdomain X of the kinase domain of Lck binds CD45 and facilitates dephosphorylation.
    Felberg J, Lefebvre DC, Lam M, Wang Y, Ng DH, Birkenhead D, Cross JL, Johnson P.
    J Biol Chem; 2004 Jan 30; 279(5):3455-62. PubMed ID: 14625311
    [Abstract] [Full Text] [Related]

  • 18. CD45 down-regulates Lck-mediated CD44 signaling and modulates actin rearrangement in T cells.
    Wong NK, Lai JC, Birkenhead D, Shaw AS, Johnson P.
    J Immunol; 2008 Nov 15; 181(10):7033-43. PubMed ID: 18981123
    [Abstract] [Full Text] [Related]

  • 19. Active Ca2+/calmodulin-dependent protein kinase II gamma B impairs positive selection of T cells by modulating TCR signaling.
    McGargill MA, Sharp LL, Bui JD, Hedrick SM, Calbo S.
    J Immunol; 2005 Jul 15; 175(2):656-64. PubMed ID: 16002660
    [Abstract] [Full Text] [Related]

  • 20. Lck-dependent Fyn activation requires C terminus-dependent targeting of kinase-active Lck to lipid rafts.
    Filipp D, Moemeni B, Ferzoco A, Kathirkamathamby K, Zhang J, Ballek O, Davidson D, Veillette A, Julius M.
    J Biol Chem; 2008 Sep 26; 283(39):26409-22. PubMed ID: 18660530
    [Abstract] [Full Text] [Related]

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