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285 related items for PubMed ID: 28743999

  • 1. Selenocysteine induces apoptosis in human glioma cells: evidence for TrxR1-targeted inhibition and signaling crosstalk.
    Fan CD, Fu XY, Zhang ZY, Cao MZ, Sun JY, Yang MF, Fu XT, Zhao SJ, Shao LR, Zhang HF, Yang XY, Sun BL.
    Sci Rep; 2017 Jul 25; 7(1):6465. PubMed ID: 28743999
    [Abstract] [Full Text] [Related]

  • 2. Enhancement of auranofin-induced lung cancer cell apoptosis by selenocystine, a natural inhibitor of TrxR1 in vitro and in vivo.
    Fan C, Zheng W, Fu X, Li X, Wong YS, Chen T.
    Cell Death Dis; 2014 Apr 24; 5(4):e1191. PubMed ID: 24763048
    [Abstract] [Full Text] [Related]

  • 3. Selenocysteine inhibits human osteosarcoma cells growth through triggering mitochondrial dysfunction and ROS-mediated p53 phosphorylation.
    Wang W, Meng FB, Wang ZX, Li X, Zhou DS.
    Cell Biol Int; 2018 May 24; 42(5):580-588. PubMed ID: 29323455
    [Abstract] [Full Text] [Related]

  • 4. Induction of S-Phase Arrest in Human Glioma Cells by Selenocysteine, a Natural Selenium-Containing Agent Via Triggering Reactive Oxygen Species-Mediated DNA Damage and Modulating MAPKs and AKT Pathways.
    Wang K, Fu XT, Li Y, Hou YJ, Yang MF, Sun JY, Yi SY, Fan CD, Fu XY, Zhai J, Sun BL.
    Neurochem Res; 2016 Jun 24; 41(6):1439-47. PubMed ID: 26846141
    [Abstract] [Full Text] [Related]

  • 5. Induction of Apoptosis in Human Glioma Cells by Fucoxanthin via Triggering of ROS-Mediated Oxidative Damage and Regulation of MAPKs and PI3K-AKT Pathways.
    Wu HL, Fu XY, Cao WQ, Xiang WZ, Hou YJ, Ma JK, Wang Y, Fan CD.
    J Agric Food Chem; 2019 Feb 27; 67(8):2212-2219. PubMed ID: 30688446
    [Abstract] [Full Text] [Related]

  • 6. Methylseleninic acid inhibits human glioma growth in vitro and in vivo by triggering ROS-dependent oxidative damage and apoptosis.
    Chen W, Hao P, Song Q, Feng X, Zhao X, Wu J, Gong Z, Zhang J, Fu X, Wang X.
    Metab Brain Dis; 2024 Apr 27; 39(4):625-633. PubMed ID: 38416338
    [Abstract] [Full Text] [Related]

  • 7. Natural borneol sensitizes human glioma cells to cisplatin-induced apoptosis by triggering ROS-mediated oxidative damage and regulation of MAPKs and PI3K/AKT pathway.
    Cao WQ, Zhai XQ, Ma JW, Fu XQ, Zhao BS, Zhang P, Fu XY.
    Pharm Biol; 2020 Dec 27; 58(1):72-79. PubMed ID: 31875760
    [Abstract] [Full Text] [Related]

  • 8. Oxidative stress induces parallel autophagy and mitochondria dysfunction in human glioma U251 cells.
    Zhang H, Kong X, Kang J, Su J, Li Y, Zhong J, Sun L.
    Toxicol Sci; 2009 Aug 27; 110(2):376-88. PubMed ID: 19451193
    [Abstract] [Full Text] [Related]

  • 9. Caudatin induces caspase-dependent apoptosis in human glioma cells with involvement of mitochondrial dysfunction and reactive oxygen species generation.
    Zhu LZ, Hou YJ, Zhao M, Yang MF, Fu XT, Sun JY, Fu XY, Shao LR, Zhang HF, Fan CD, Gao HL, Sun BL.
    Cell Biol Toxicol; 2016 Aug 27; 32(4):333-45. PubMed ID: 27184666
    [Abstract] [Full Text] [Related]

  • 10. Natural borneol, a monoterpenoid compound, potentiates selenocystine-induced apoptosis in human hepatocellular carcinoma cells by enhancement of cellular uptake and activation of ROS-mediated DNA damage.
    Su J, Lai H, Chen J, Li L, Wong YS, Chen T, Li X.
    PLoS One; 2013 Aug 27; 8(5):e63502. PubMed ID: 23700426
    [Abstract] [Full Text] [Related]

  • 11. Piperlongumine as a direct TrxR1 inhibitor with suppressive activity against gastric cancer.
    Zou P, Xia Y, Ji J, Chen W, Zhang J, Chen X, Rajamanickam V, Chen G, Wang Z, Chen L, Wang Y, Yang S, Liang G.
    Cancer Lett; 2016 May 28; 375(1):114-126. PubMed ID: 26963494
    [Abstract] [Full Text] [Related]

  • 12. Enhancement of auranofin-induced apoptosis in MCF-7 human breast cells by selenocystine, a synergistic inhibitor of thioredoxin reductase.
    Liu C, Liu Z, Li M, Li X, Wong YS, Ngai SM, Zheng W, Zhang Y, Chen T.
    PLoS One; 2013 May 28; 8(1):e53945. PubMed ID: 23342042
    [Abstract] [Full Text] [Related]

  • 13. DSePA Antagonizes High Glucose-Induced Neurotoxicity: Evidences for DNA Damage-Mediated p53 Phosphorylation and MAPKs and AKT Pathways.
    Wang K, Fu XY, Fu XT, Hou YJ, Fang J, Zhang S, Yang MF, Li DW, Mao LL, Sun JY, Yuan H, Yang XY, Fan CD, Zhang ZY, Sun BL.
    Mol Neurobiol; 2016 Sep 28; 53(7):4363-74. PubMed ID: 26232068
    [Abstract] [Full Text] [Related]

  • 14. EF24 induces ROS-mediated apoptosis via targeting thioredoxin reductase 1 in gastric cancer cells.
    Zou P, Xia Y, Chen W, Chen X, Ying S, Feng Z, Chen T, Ye Q, Wang Z, Qiu C, Yang S, Liang G.
    Oncotarget; 2016 Apr 05; 7(14):18050-64. PubMed ID: 26919110
    [Abstract] [Full Text] [Related]

  • 15. Deoxypodophyllotoxin triggers parthanatos in glioma cells via induction of excessive ROS.
    Ma D, Lu B, Feng C, Wang C, Wang Y, Luo T, Feng J, Jia H, Chi G, Luo Y, Ge P.
    Cancer Lett; 2016 Feb 28; 371(2):194-204. PubMed ID: 26683770
    [Abstract] [Full Text] [Related]

  • 16. Withaferin A, a natural thioredoxin reductase 1 (TrxR1) inhibitor, synergistically enhances the antitumor efficacy of sorafenib through ROS-mediated ER stress and DNA damage in hepatocellular carcinoma cells.
    Chen X, Zhu N, Wu Y, Zhang Y, Zhang Y, Jin K, Zhou Z, Chen G, Wang J.
    Phytomedicine; 2024 Jun 28; 128():155317. PubMed ID: 38537439
    [Abstract] [Full Text] [Related]

  • 17. Strategy to enhance the therapeutic effect of doxorubicin in human hepatocellular carcinoma by selenocystine, a synergistic agent that regulates the ROS-mediated signaling.
    Fan C, Zheng W, Fu X, Li X, Wong YS, Chen T.
    Oncotarget; 2014 May 15; 5(9):2853-63. PubMed ID: 24797310
    [Abstract] [Full Text] [Related]

  • 18. Piperlongumine potentiates the antitumor efficacy of oxaliplatin through ROS induction in gastric cancer cells.
    Zhang P, Shi L, Zhang T, Hong L, He W, Cao P, Shen X, Zheng P, Xia Y, Zou P.
    Cell Oncol (Dordr); 2019 Dec 15; 42(6):847-860. PubMed ID: 31493144
    [Abstract] [Full Text] [Related]

  • 19. A diterpenoid derivate compound targets selenocysteine of thioredoxin reductases and induces Bax/Bak-independent apoptosis.
    Liu J, Mu C, Yue W, Li J, Ma B, Zhao L, Liu L, Chen Q, Yan C, Liu H, Hao X, Zhu Y.
    Free Radic Biol Med; 2013 Oct 15; 63():485-94. PubMed ID: 23732520
    [Abstract] [Full Text] [Related]

  • 20. Selective killing of gastric cancer cells by a small molecule via targeting TrxR1 and ROS-mediated ER stress activation.
    Chen W, Zou P, Zhao Z, Weng Q, Chen X, Ying S, Ye Q, Wang Z, Ji J, Liang G.
    Oncotarget; 2016 Mar 29; 7(13):16593-609. PubMed ID: 26919094
    [Abstract] [Full Text] [Related]

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