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Journal Abstract Search

561 related items for PubMed ID: 28752047

  • 21. The S20G substitution in hIAPP is more amyloidogenic and cytotoxic than wild-type hIAPP in mouse islets.
    Meier DT, Entrup L, Templin AT, Hogan MF, Mellati M, Zraika S, Hull RL, Kahn SE.
    Diabetologia; 2016 Oct; 59(10):2166-71. PubMed ID: 27393137
    [Abstract] [Full Text] [Related]

  • 22. The islet tissue plasminogen activator/plasmin system is upregulated with human islet amyloid polypeptide aggregation and protects beta cells from aggregation-induced toxicity.
    Esser N, Hogan MF, Templin AT, Akter R, Fountaine BS, Castillo JJ, El-Osta A, Manathunga L, Zhyvoloup A, Raleigh DP, Zraika S, Hull RL, Kahn SE.
    Diabetologia; 2024 Sep; 67(9):1897-1911. PubMed ID: 39245780
    [Abstract] [Full Text] [Related]

  • 23. α1-antitrypsin increases interleukin-1 receptor antagonist production during pancreatic islet graft transplantation.
    Abecassis A, Schuster R, Shahaf G, Ozeri E, Green R, Ochayon DE, Rider P, Lewis EC.
    Cell Mol Immunol; 2014 Jul; 11(4):377-86. PubMed ID: 25000533
    [Abstract] [Full Text] [Related]

  • 24. Amyloid-induced β-cell dysfunction and islet inflammation are ameliorated by 4-phenylbutyrate (PBA) treatment.
    Montane J, de Pablo S, Castaño C, Rodríguez-Comas J, Cadavez L, Obach M, Visa M, Alcarraz-Vizán G, Sanchez-Martinez M, Nonell-Canals A, Parrizas M, Servitja JM, Novials A.
    FASEB J; 2017 Dec; 31(12):5296-5306. PubMed ID: 28821639
    [Abstract] [Full Text] [Related]

  • 25. Adenoviral overexpression of interleukin-1 receptor antagonist protein increases beta-cell replication in rat pancreatic islets.
    Téllez N, Montolio M, Biarnés M, Castaño E, Soler J, Montanya E.
    Gene Ther; 2005 Jan; 12(2):120-8. PubMed ID: 15578044
    [Abstract] [Full Text] [Related]

  • 26. The DPP-4 inhibitor linagliptin restores β-cell function and survival in human isolated islets through GLP-1 stabilization.
    Shah P, Ardestani A, Dharmadhikari G, Laue S, Schumann DM, Kerr-Conte J, Pattou F, Klein T, Maedler K.
    J Clin Endocrinol Metab; 2013 Jul; 98(7):E1163-72. PubMed ID: 23633194
    [Abstract] [Full Text] [Related]

  • 27. The human serum protein C4b-binding protein inhibits pancreatic IAPP-induced inflammasome activation.
    Kulak K, Westermark GT, Papac-Milicevic N, Renström E, Blom AM, King BC.
    Diabetologia; 2017 Aug; 60(8):1522-1533. PubMed ID: 28500395
    [Abstract] [Full Text] [Related]

  • 28. Free fatty acids induce a proinflammatory response in islets via the abundantly expressed interleukin-1 receptor I.
    Böni-Schnetzler M, Boller S, Debray S, Bouzakri K, Meier DT, Prazak R, Kerr-Conte J, Pattou F, Ehses JA, Schuit FC, Donath MY.
    Endocrinology; 2009 Dec; 150(12):5218-29. PubMed ID: 19819943
    [Abstract] [Full Text] [Related]

  • 29. Induction of endoplasmic reticulum stress-induced beta-cell apoptosis and accumulation of polyubiquitinated proteins by human islet amyloid polypeptide.
    Huang CJ, Haataja L, Gurlo T, Butler AE, Wu X, Soeller WC, Butler PC.
    Am J Physiol Endocrinol Metab; 2007 Dec; 293(6):E1656-62. PubMed ID: 17911343
    [Abstract] [Full Text] [Related]

  • 30. Targeting the IL-1β/IL-1Ra pathways for the aggregation of human islet amyloid polypeptide in an ex vivo organ culture system of the intervertebral disc.
    Wu X, Liao Z, Wang K, Hua W, Liu X, Song Y, Zhang Y, Yang S, Yang C.
    Exp Mol Med; 2019 Sep 25; 51(9):1-16. PubMed ID: 31554783
    [Abstract] [Full Text] [Related]

  • 31. Small interfering RNA-mediated suppression of proislet amyloid polypeptide expression inhibits islet amyloid formation and enhances survival of human islets in culture.
    Marzban L, Tomas A, Becker TC, Rosenberg L, Oberholzer J, Fraser PE, Halban PA, Verchere CB.
    Diabetes; 2008 Nov 25; 57(11):3045-55. PubMed ID: 18694973
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  • 33. IL-1beta receptor blockade protects islets against pro-inflammatory cytokine induced necrosis and apoptosis.
    Schwarznau A, Hanson MS, Sperger JM, Schram BR, Danobeitia JS, Greenwood KK, Vijayan A, Fernandez LA.
    J Cell Physiol; 2009 Aug 25; 220(2):341-7. PubMed ID: 19334038
    [Abstract] [Full Text] [Related]

  • 34. ABCA1 deficiency and cellular cholesterol accumulation increases islet amyloidogenesis in mice.
    Wijesekara N, Kaur A, Westwell-Roper C, Nackiewicz D, Soukhatcheva G, Hayden MR, Verchere CB.
    Diabetologia; 2016 Jun 25; 59(6):1242-6. PubMed ID: 26970755
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  • 38. IL-1 antagonism reduces hyperglycemia and tissue inflammation in the type 2 diabetic GK rat.
    Ehses JA, Lacraz G, Giroix MH, Schmidlin F, Coulaud J, Kassis N, Irminger JC, Kergoat M, Portha B, Homo-Delarche F, Donath MY.
    Proc Natl Acad Sci U S A; 2009 Aug 18; 106(33):13998-4003. PubMed ID: 19666548
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  • 40. Islet amyloid polypeptide aggregation exerts cytotoxic and proinflammatory effects on the islet vasculature in mice.
    Castillo JJ, Aplin AC, Hackney DJ, Hogan MF, Esser N, Templin AT, Akter R, Kahn SE, Raleigh DP, Zraika S, Hull RL.
    Diabetologia; 2022 Oct 18; 65(10):1687-1700. PubMed ID: 35871651
    [Abstract] [Full Text] [Related]

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