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Journal Abstract Search

150 related items for PubMed ID: 28756483

  • 21. A target within the target: probing cruzain's P1' site to define structural determinants for the Chagas' disease protease.
    Brinen LS, Hansell E, Cheng J, Roush WR, McKerrow JH, Fletterick RJ.
    Structure; 2000 Aug 15; 8(8):831-40. PubMed ID: 10997902
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  • 25. Cruzain structures: apocruzain and cruzain bound to S-methyl thiomethanesulfonate and implications for drug design.
    Barbosa da Silva E, Dall E, Briza P, Brandstetter H, Ferreira RS.
    Acta Crystallogr F Struct Biol Commun; 2019 Jun 01; 75(Pt 6):419-427. PubMed ID: 31204688
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  • 26. Novel cruzain inhibitors for the treatment of Chagas' disease.
    Rogers KE, Keränen H, Durrant JD, Ratnam J, Doak A, Arkin MR, McCammon JA.
    Chem Biol Drug Des; 2012 Sep 01; 80(3):398-405. PubMed ID: 22613098
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  • 29. Computational identification of uncharacterized cruzain binding sites.
    Durrant JD, Keränen H, Wilson BA, McCammon JA.
    PLoS Negl Trop Dis; 2010 May 11; 4(5):e676. PubMed ID: 20485483
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  • 30. S1 subsite specificity of a recombinant cysteine proteinase, CPB, of Leishmania mexicana compared with cruzain, human cathepsin L and papain using substrates containing non-natural basic amino acids.
    Alves LC, Melo RL, Sanderson SJ, Mottram JC, Coombs GH, Caliendo G, Santagada V, Juliano L, Juliano MA.
    Eur J Biochem; 2001 Mar 11; 268(5):1206-12. PubMed ID: 11231271
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  • 31. The substrate specificity of cruzipain 2, a cysteine protease isoform from Trypanosoma cruzi.
    dos Reis FC, Júdice WA, Juliano MA, Juliano L, Scharfstein J, Lima AP.
    FEMS Microbiol Lett; 2006 Jun 11; 259(2):215-20. PubMed ID: 16734782
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  • 32. Self-Masked Aldehyde Inhibitors: A Novel Strategy for Inhibiting Cysteine Proteases.
    Li L, Chenna BC, Yang KS, Cole TR, Goodall ZT, Giardini M, Moghadamchargari Z, Hernandez EA, Gomez J, Calvet CM, Bernatchez JA, Mellott DM, Zhu J, Rademacher A, Thomas D, Blankenship LR, Drelich A, Laganowsky A, Tseng CK, Liu WR, Wand AJ, Cruz-Reyes J, Siqueira-Neto JL, Meek TD.
    J Med Chem; 2021 Aug 12; 64(15):11267-11287. PubMed ID: 34288674
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  • 33. Ligand-induced conformational selection predicts the selectivity of cysteine protease inhibitors.
    Sartori GR, Leitão A, Montanari CA, Laughton CA.
    PLoS One; 2019 Aug 12; 14(12):e0222055. PubMed ID: 31856175
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  • 34. Investigating the Lack of Translation from Cruzain Inhibition to Trypanosoma cruzi Activity with Machine Learning and Chemical Space Analyses.
    Lameiro RF, Montanari CA.
    ChemMedChem; 2023 Mar 14; 18(6):e202200434. PubMed ID: 36692246
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  • 35. Crystal structures of reversible ketone-Based inhibitors of the cysteine protease cruzain.
    Huang L, Brinen LS, Ellman JA.
    Bioorg Med Chem; 2003 Jan 02; 11(1):21-9. PubMed ID: 12467703
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  • 36. Aryl ureas represent a new class of anti-trypanosomal agents.
    Du X, Hansell E, Engel JC, Caffrey CR, Cohen FE, McKerrow JH.
    Chem Biol; 2000 Sep 02; 7(9):733-42. PubMed ID: 10980453
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  • 37. Cysteine protease inhibitors alter Golgi complex ultrastructure and function in Trypanosoma cruzi.
    Engel JC, Doyle PS, Palmer J, Hsieh I, Bainton DF, McKerrow JH.
    J Cell Sci; 1998 Mar 02; 111 ( Pt 5)():597-606. PubMed ID: 9454733
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  • 38. The gene repertoire of the main cysteine protease of Trypanosoma cruzi, cruzipain, reveals four sub-types with distinct active sites.
    Santos VC, Oliveira AER, Campos ACB, Reis-Cunha JL, Bartholomeu DC, Teixeira SMR, Lima APCA, Ferreira RS.
    Sci Rep; 2021 Sep 14; 11(1):18231. PubMed ID: 34521898
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  • 39. Solution structure and backbone dynamics of the Trypanosoma cruzi cysteine protease inhibitor chagasin.
    Salmon D, do Aido-Machado R, Diehl A, Leidert M, Schmetzer O, de A Lima AP, Scharfstein J, Oschkinat H, Pires JR.
    J Mol Biol; 2006 Apr 14; 357(5):1511-21. PubMed ID: 16490204
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  • 40. Tetrafluorophenoxymethyl ketone cruzain inhibitors with improved pharmacokinetic properties as therapeutic leads for Chagas' disease.
    Neitz RJ, Bryant C, Chen S, Gut J, Hugo Caselli E, Ponce S, Chowdhury S, Xu H, Arkin MR, Ellman JA, Renslo AR.
    Bioorg Med Chem Lett; 2015 Nov 01; 25(21):4834-4837. PubMed ID: 26144347
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