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247 related items for PubMed ID: 28757065

  • 1. Design and synthesis of piperazine acetate podophyllotoxin ester derivatives targeting tubulin depolymerization as new anticancer agents.
    Sun WX, Ji YJ, Wan Y, Han HW, Lin HY, Lu GH, Qi JL, Wang XM, Yang YH.
    Bioorg Med Chem Lett; 2017 Sep 01; 27(17):4066-4074. PubMed ID: 28757065
    [Abstract] [Full Text] [Related]

  • 2. Investigation of podophyllotoxin esters as potential anticancer agents: synthesis, biological studies and tubulin inhibition properties.
    Shareef MA, Duscharla D, Ramasatyaveni G, Dhoke NR, Das A, Ummanni R, Srivastava AK.
    Eur J Med Chem; 2015 Jan 07; 89():128-37. PubMed ID: 25462233
    [Abstract] [Full Text] [Related]

  • 3. Synthesis and biological evaluation of podophyllotoxin congeners as tubulin polymerization inhibitors.
    Kamal A, Srinivasa Reddy T, Polepalli S, Shalini N, Reddy VG, Subba Rao AV, Jain N, Shankaraiah N.
    Bioorg Med Chem; 2014 Oct 01; 22(19):5466-75. PubMed ID: 25131956
    [Abstract] [Full Text] [Related]

  • 4. Design, synthesis, biological evaluation, and 3D-QSAR analysis of podophyllotoxin-dioxazole combination as tubulin targeting anticancer agents.
    Wang ZZ, Sun WX, Wang X, Zhang YH, Qiu HY, Qi JL, Pang YJ, Lu GH, Wang XM, Yu FG, Yang YH.
    Chem Biol Drug Des; 2017 Aug 01; 90(2):236-243. PubMed ID: 28079286
    [Abstract] [Full Text] [Related]

  • 5. Design, synthesis and anti-cancer activity evaluation of podophyllotoxin-norcantharidin hybrid drugs.
    Han HW, Qiu HY, Hu C, Sun WX, Yang RW, Qi JL, Wang XM, Lu GH, Yang YH.
    Bioorg Med Chem Lett; 2016 Jul 15; 26(14):3237-3242. PubMed ID: 27262599
    [Abstract] [Full Text] [Related]

  • 6. Design and synthesis of pyrazole-oxindole conjugates targeting tubulin polymerization as new anticancer agents.
    Kamal A, Shaik AB, Jain N, Kishor C, Nagabhushana A, Supriya B, Bharath Kumar G, Chourasiya SS, Suresh Y, Mishra RK, Addlagatta A.
    Eur J Med Chem; 2015 Mar 06; 92():501-13. PubMed ID: 25599948
    [Abstract] [Full Text] [Related]

  • 7. Synthesis of d-ring modified acid hydrazide derivatives of podophyllotoxin and their anticancer studies as Tubulin inhibiting agents.
    Nerella S, Kankala S, Paidakula S, Gavaji B.
    Bioorg Chem; 2020 Jan 06; 94():103384. PubMed ID: 31776036
    [Abstract] [Full Text] [Related]

  • 8. Synthesis and biological evaluation of a series of podophyllotoxins derivatives as a class of potent antitubulin agents.
    Liu Y, Wei D, Zhao Y, Cheng W, Lu Y, Ma Y, Li X, Han C, Wei Y, Cao H, Zhao C.
    Bioorg Med Chem; 2012 Nov 01; 20(21):6285-95. PubMed ID: 23022053
    [Abstract] [Full Text] [Related]

  • 9. Design and synthesis of 1,2,3-triazolo linked benzo[d]imidazo[2,1-b]thiazole conjugates as tubulin polymerization inhibitors.
    Shaik SP, Vishnuvardhan MVPS, Sultana F, Subba Rao AV, Bagul C, Bhattacharjee D, Kapure JS, Jain N, Kamal A.
    Bioorg Med Chem; 2017 Jul 01; 25(13):3285-3297. PubMed ID: 28462842
    [Abstract] [Full Text] [Related]

  • 10. Novel Podophyllotoxin Derivatives as Potential Tubulin Inhibitors: Design, Synthesis, and Antiproliferative Activity Evaluation.
    Han HW, Lin HY, He DL, Ren Y, Sun WX, Liang L, Du MH, Li DC, Chu YC, Yang MK, Wang XM, Yang YH.
    Chem Biodivers; 2018 Nov 01; 15(11):e1800289. PubMed ID: 30194898
    [Abstract] [Full Text] [Related]

  • 11. Synthesis of a terphenyl substituted 4-aza-2,3-didehydropodophyllotoxin analogues as inhibitors of tubulin polymerization and apoptosis inducers.
    Kamal A, Tamboli JR, Nayak VL, Adil SF, Vishnuvardhan MV, Ramakrishna S.
    Bioorg Med Chem; 2014 May 01; 22(9):2714-23. PubMed ID: 24721832
    [Abstract] [Full Text] [Related]

  • 12. Synthesis of Combretastatin-A4 Carboxamidest that Mimic Sulfonyl Piperazines by a Molecular Hybridization Approach: in vitro Cytotoxicity Evaluation and Inhibition of Tubulin Polymerization.
    Jadala C, Sathish M, Anchi P, Tokala R, Lakshmi UJ, Reddy VG, Shankaraiah N, Godugu C, Kamal A.
    ChemMedChem; 2019 Dec 17; 14(24):2052-2060. PubMed ID: 31674147
    [Abstract] [Full Text] [Related]

  • 13. One-pot synthesis and biological evaluation of N-(aminosulfonyl)-4-podophyllotoxin carbamates as potential anticancer agents.
    Xu XH, Guan XW, Feng SL, Ma YZ, Chen SW, Hui L.
    Bioorg Med Chem Lett; 2017 Jul 01; 27(13):2890-2894. PubMed ID: 28512026
    [Abstract] [Full Text] [Related]

  • 14. Design, synthesis of combretastatin A-4 piperazine derivatives as potential antitumor agents by inhibiting tubulin polymerization and inducing autophagy in HCT116 cells.
    Zhang H, Li M, Zhou X, Tang L, Chen G, Zhang Y.
    Eur J Med Chem; 2024 Jun 05; 272():116497. PubMed ID: 38759453
    [Abstract] [Full Text] [Related]

  • 15. Synthesis and biological evaluation of 4-aza-2,3-dihydropyridophenanthrolines as tubulin polymerization inhibitors.
    Kamal A, Srinivasa Reddy T, Polepalli S, Paidakula S, Srinivasulu V, Ganga Reddy V, Jain N, Shankaraiah N.
    Bioorg Med Chem Lett; 2014 Aug 01; 24(15):3356-60. PubMed ID: 24953821
    [Abstract] [Full Text] [Related]

  • 16. The ester derivatives obtained by C-ring modification of podophyllotoxin induce apoptosis and inhibited proliferation in PC-3M cells via down-regulation of PI3K/Akt signaling pathway.
    Zhao Y, Li D, Wei M, Du R, Yan Z.
    Bioorg Med Chem Lett; 2021 Aug 15; 46():128174. PubMed ID: 34098082
    [Abstract] [Full Text] [Related]

  • 17. Synthesis and Biological evaluation of novel 4β-[(5-substituted)-1,2,3,4-tetrazolyl] podophyllotoxins as anticancer compounds.
    Hyder I, Yedlapudi D, Kalivendi SV, Khazir J, Ismail T, Nalla N, Miryala S, Sampath Kumar HM.
    Bioorg Med Chem Lett; 2015 Jul 15; 25(14):2860-3. PubMed ID: 26022842
    [Abstract] [Full Text] [Related]

  • 18. Synthesis and biological evaluation of arylcinnamide linked combretastatin-A4 hybrids as tubulin polymerization inhibitors and apoptosis inducing agents.
    Kamal A, Bajee S, Lakshma Nayak V, Venkata Subba Rao A, Nagaraju B, Ratna Reddy C, Jeevak Sopanrao K, Alarifi A.
    Bioorg Med Chem Lett; 2016 Jun 15; 26(12):2957-2964. PubMed ID: 27161282
    [Abstract] [Full Text] [Related]

  • 19. Synthesis and biological evaluation of podophyllotoxin derivatives as selective antitumor agents.
    Wu GR, Xu B, Yang YQ, Zhang XY, Fang K, Ma T, Wang H, Xue NN, Chen M, Guo WB, Jia XH, Wang PL, Lei HM.
    Eur J Med Chem; 2018 Jul 15; 155():183-196. PubMed ID: 29886322
    [Abstract] [Full Text] [Related]

  • 20. Design, synthesis, molecular modeling, and biological evaluation of pyrazole-naphthalene derivatives as potential anticancer agents on MCF-7 breast cancer cells by inhibiting tubulin polymerization.
    Wang G, Liu W, Peng Z, Huang Y, Gong Z, Li Y.
    Bioorg Chem; 2020 Oct 15; 103():104141. PubMed ID: 32750611
    [Abstract] [Full Text] [Related]

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