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164 related items for PubMed ID: 28757443

  • 1. Synthetic studies of (23S,25R)-1α,25-dihydroxyvitamin D3 26,23-lactone (calcitriol lactone) and its derivatives.
    Akagi Y, Nagata A, Odagi M, Nagasawa K.
    J Steroid Biochem Mol Biol; 2018 Mar; 177():240-246. PubMed ID: 28757443
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  • 2. 1alpha,25-Dihydroxyvitamin D(3)-26,23-lactam analogues function as vitamin D receptor antagonists in human and rodent cells.
    Ishizuka S, Kurihara N, Hiruma Y, Miura D, Namekawa J, Tamura A, Kato-Nakamura Y, Nakano Y, Takenouchi K, Hashimoto Y, Nagasawa K, Roodman GD.
    J Steroid Biochem Mol Biol; 2008 Jun; 110(3-5):269-77. PubMed ID: 18501591
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  • 3. Antagonistic action of novel 1alpha,25-dihydroxyvitamin D3-26, 23-lactone analogs on differentiation of human leukemia cells (HL-60) induced by 1alpha,25-dihydroxyvitamin D3.
    Miura D, Manabe K, Ozono K, Saito M, Gao Q, Norman AW, Ishizuka S.
    J Biol Chem; 1999 Jun 04; 274(23):16392-9. PubMed ID: 10347199
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  • 4. Practical synthesis and evaluation of the biological activities of 1alpha,25-dihydroxyvitamin D3 antagonists, 1alpha,25-dihydroxyvitamin D3-26,23-lactams. Designed on the basis of the helix 12-folding inhibition hypothesis.
    Nakano Y, Kato Y, Imai K, Ochiai E, Namekawa J, Ishizuka S, Takenouchi K, Tanatani A, Hashimoto Y, Nagasawa K.
    J Med Chem; 2006 Apr 20; 49(8):2398-406. PubMed ID: 16610783
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  • 5. Further synthetic and biological studies on vitamin D hormone antagonists based on C24-alkylation and C2alpha-functionalization of 25-dehydro-1alpha-hydroxyvitamin D(3)-26,23-lactones.
    Saito N, Matsunaga T, Saito H, Anzai M, Takenouchi K, Miura D, Namekawa J, Ishizuka S, Kittaka A.
    J Med Chem; 2006 Nov 30; 49(24):7063-75. PubMed ID: 17125259
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  • 6. A structural basis for the species-specific antagonism of 26,23-lactones on vitamin D signaling.
    Peräkylä M, Molnár F, Carlberg C.
    Chem Biol; 2004 Aug 30; 11(8):1147-56. PubMed ID: 15324816
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  • 7. Regulation of the vitamin D receptor by vitamin D lactam derivatives.
    Asano L, Waku T, Abe R, Kuwabara N, Ito I, Yanagisawa J, Nagasawa K, Shimizu T.
    FEBS Lett; 2016 Sep 30; 590(18):3270-9. PubMed ID: 27500498
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  • 10. 1alpha,25-dihydroxyvitamin D(3)-26,23-lactone analogs antagonize differentiation of human leukemia cells (HL-60 cells) but not of human acute promyelocytic leukemia cells (NB4 cells).
    Miura D, Manabe K, Gao Q, Norman AW, Ishizuka S.
    FEBS Lett; 1999 Oct 29; 460(2):297-302. PubMed ID: 10544253
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  • 14. (23S)- and (23R)-25-dehydro-1alpha-hydroxyvitamin D(3)-26,23-lactone function as antagonists of vitamin D receptor-mediated genomic actions of 1alpha,25-dihydroxyvitamin D(3).
    Ishizuka S, Miura D, Ozono K, Saito M, Eguchi H, Chokki M, Norman AW.
    Steroids; 2001 Oct 29; 66(3-5):227-37. PubMed ID: 11179730
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  • 15. Novel vitamin D3 analogs, 1alpha, 25(OH)2D(3)-26, 23-lactam (DLAMs), antagonize bone resorption via suppressing RANKL expression in osteoblasts.
    Inada M, Tsukamoto K, Hirata M, Takita M, Nagasawa K, Miyaura C.
    Biochem Biophys Res Commun; 2008 Aug 01; 372(3):434-9. PubMed ID: 18489902
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  • 16. Highly potent vitamin D receptor antagonists: design, synthesis, and biological evaluation.
    Saito N, Kittaka A.
    Chembiochem; 2006 Oct 01; 7(10):1479-90. PubMed ID: 16871612
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  • 17. Recent results on A-ring modification of 1alpha,25-dihydroxyvitamin D3: design and synthesis of VDR-agonists and antagonists with high biological activity.
    Saito N, Honzawa S, Kittaka A.
    Curr Top Med Chem; 2006 Oct 01; 6(12):1273-88. PubMed ID: 16848741
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  • 18. Dramatic enhancement of antagonistic activity on vitamin D receptor: a double functionalization of 1alpha-hydroxyvitamin D3 26,23-lactones.
    Saito N, Saito H, Anzai M, Yoshida A, Fujishima T, Takenouchi K, Miura D, Ishizuka S, Takayama H, Kittaka A.
    Org Lett; 2003 Dec 11; 5(25):4859-62. PubMed ID: 14653692
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  • 19. Antagonistic action of novel 1alpha,25-dihydroxyvitamin D(3)-26, 23-lactone analogs on 25-hydroxyvitamin-D(3)-24-hydroxylase gene expression induced by 1alpha,25-dihydroxy-vitamin D(3) in human promyelocytic leukemia (HL-60) cells.
    Ishizuka S, Miura D, Eguchi H, Ozono K, Chokki M, Kamimura T, Norman AW.
    Arch Biochem Biophys; 2000 Aug 01; 380(1):92-102. PubMed ID: 10900137
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  • 20. (23S)-25-Dehydro-1{alpha}-hydroxyvitamin D3-26,23-lactone, a vitamin D receptor antagonist that inhibits osteoclast formation and bone resorption in bone marrow cultures from patients with Paget's disease.
    Ishizuka S, Kurihara N, Reddy SV, Cornish J, Cundy T, Roodman GD.
    Endocrinology; 2005 Apr 01; 146(4):2023-30. PubMed ID: 15618361
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