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Journal Abstract Search

174 related items for PubMed ID: 28777084

  • 1. The role of conserved surface hydrophobic residues in the carbapenemase activity of the class D β-lactamases.
    Toth M, Smith CA, Antunes NT, Stewart NK, Maltz L, Vakulenko SB.
    Acta Crystallogr D Struct Biol; 2017 Aug 01; 73(Pt 8):692-701. PubMed ID: 28777084
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  • 2. Structural Insights into the Mechanism of Carbapenemase Activity of the OXA-48 β-Lactamase.
    Smith CA, Stewart NK, Toth M, Vakulenko SB.
    Antimicrob Agents Chemother; 2019 Oct 01; 63(10):. PubMed ID: 31358584
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  • 4. C6 Hydroxymethyl-Substituted Carbapenem MA-1-206 Inhibits the Major Acinetobacter baumannii Carbapenemase OXA-23 by Impeding Deacylation.
    Stewart NK, Toth M, Alqurafi MA, Chai W, Nguyen TQ, Quan P, Lee M, Buynak JD, Smith CA, Vakulenko SB.
    mBio; 2022 Jun 28; 13(3):e0036722. PubMed ID: 35420470
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  • 8. Structures of the class D carbapenemase OXA-24 from Acinetobacter baumannii in complex with doripenem.
    Schneider KD, Ortega CJ, Renck NA, Bonomo RA, Powers RA, Leonard DA.
    J Mol Biol; 2011 Mar 04; 406(4):583-94. PubMed ID: 21215758
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  • 9. Local interactions with the Glu166 base and the conformation of an active site loop play key roles in carbapenem hydrolysis by the KPC-2 β-lactamase.
    Furey IM, Mehta SC, Sankaran B, Hu L, Prasad BVV, Palzkill T.
    J Biol Chem; 2021 Mar 04; 296():100799. PubMed ID: 34022225
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  • 10. Carbapenem resistance in Acinetobacter baumannii: mechanisms and epidemiology.
    Poirel L, Nordmann P.
    Clin Microbiol Infect; 2006 Sep 04; 12(9):826-36. PubMed ID: 16882287
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  • 11. Structural Basis for Enhancement of Carbapenemase Activity in the OXA-51 Family of Class D β-Lactamases.
    Smith CA, Antunes NT, Stewart NK, Frase H, Toth M, Kantardjieff KA, Vakulenko S.
    ACS Chem Biol; 2015 Aug 21; 10(8):1791-6. PubMed ID: 26042471
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  • 13. Class D β-lactamases: are they all carbapenemases?
    Antunes NT, Lamoureaux TL, Toth M, Stewart NK, Frase H, Vakulenko SB.
    Antimicrob Agents Chemother; 2014 Aug 21; 58(4):2119-25. PubMed ID: 24468778
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  • 15. The basis for carbapenem hydrolysis by class A β-lactamases: a combined investigation using crystallography and simulations.
    Fonseca F, Chudyk EI, van der Kamp MW, Correia A, Mulholland AJ, Spencer J.
    J Am Chem Soc; 2012 Nov 07; 134(44):18275-85. PubMed ID: 23030300
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  • 16. KPC-2 β-lactamase enables carbapenem antibiotic resistance through fast deacylation of the covalent intermediate.
    Mehta SC, Furey IM, Pemberton OA, Boragine DM, Chen Y, Palzkill T.
    J Biol Chem; 2021 Nov 07; 296():100155. PubMed ID: 33273017
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  • 17. Kinetic and structural requirements for carbapenemase activity in GES-type β-lactamases.
    Stewart NK, Smith CA, Frase H, Black DJ, Vakulenko SB.
    Biochemistry; 2015 Jan 20; 54(2):588-97. PubMed ID: 25485972
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  • 18. Mechanistic Basis of OXA-48-like β-Lactamases' Hydrolysis of Carbapenems.
    Stojanoski V, Hu L, Sankaran B, Wang F, Tao P, Prasad BVV, Palzkill T.
    ACS Infect Dis; 2021 Feb 12; 7(2):445-460. PubMed ID: 33492952
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  • 19. Multiple substitutions lead to increased loop flexibility and expanded specificity in Acinetobacter baumannii carbapenemase OXA-239.
    Harper TM, June CM, Taracila MA, Bonomo RA, Powers RA, Leonard DA.
    Biochem J; 2018 Jan 11; 475(1):273-288. PubMed ID: 29229762
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  • 20. Conformational flexibility in carbapenem hydrolysis drives substrate specificity of the class D carbapenemase OXA-24/40.
    Mitchell JM, June CM, Baggett VL, Lowe BC, Ruble JF, Bonomo RA, Leonard DA, Powers RA.
    J Biol Chem; 2022 Jul 11; 298(7):102127. PubMed ID: 35709986
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