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Journal Abstract Search

664 related items for PubMed ID: 28806057

  • 1. Rational Design and Multibiological Profiling of Novel Donepezil-Trolox Hybrids against Alzheimer's Disease, with Cholinergic, Antioxidant, Neuroprotective, and Cognition Enhancing Properties.
    Cai P, Fang SQ, Yang XL, Wu JJ, Liu QH, Hong H, Wang XB, Kong LY.
    ACS Chem Neurosci; 2017 Nov 15; 8(11):2496-2511. PubMed ID: 28806057
    [Abstract] [Full Text] [Related]

  • 2. Donepezil-butylated hydroxytoluene (BHT) hybrids as Anti-Alzheimer's disease agents with cholinergic, antioxidant, and neuroprotective properties.
    Cai P, Fang SQ, Yang HL, Yang XL, Liu QH, Kong LY, Wang XB.
    Eur J Med Chem; 2018 Sep 05; 157():161-176. PubMed ID: 30096650
    [Abstract] [Full Text] [Related]

  • 3. Rational modification of donepezil as multifunctional acetylcholinesterase inhibitors for the treatment of Alzheimer's disease.
    Wang ZM, Cai P, Liu QH, Xu DQ, Yang XL, Wu JJ, Kong LY, Wang XB.
    Eur J Med Chem; 2016 Nov 10; 123():282-297. PubMed ID: 27484514
    [Abstract] [Full Text] [Related]

  • 4. Synthesis and evaluation of multi-target-directed ligands for the treatment of Alzheimer's disease based on the fusion of donepezil and melatonin.
    Wang J, Wang ZM, Li XM, Li F, Wu JJ, Kong LY, Wang XB.
    Bioorg Med Chem; 2016 Sep 15; 24(18):4324-4338. PubMed ID: 27460699
    [Abstract] [Full Text] [Related]

  • 5. Donepezil + propargylamine + 8-hydroxyquinoline hybrids as new multifunctional metal-chelators, ChE and MAO inhibitors for the potential treatment of Alzheimer's disease.
    Wang L, Esteban G, Ojima M, Bautista-Aguilera OM, Inokuchi T, Moraleda I, Iriepa I, Samadi A, Youdim MB, Romero A, Soriano E, Herrero R, Fernández Fernández AP, Ricardo-Martínez-Murillo, Marco-Contelles J, Unzeta M.
    Eur J Med Chem; 2014 Jun 10; 80():543-61. PubMed ID: 24813882
    [Abstract] [Full Text] [Related]

  • 6. Design, synthesis and biological activity of novel donepezil derivatives bearing N-benzyl pyridinium moiety as potent and dual binding site acetylcholinesterase inhibitors.
    Lan JS, Zhang T, Liu Y, Yang J, Xie SS, Liu J, Miao ZY, Ding Y.
    Eur J Med Chem; 2017 Jun 16; 133():184-196. PubMed ID: 28388521
    [Abstract] [Full Text] [Related]

  • 7. Design, synthesis, and evaluation of salicyladimine derivatives as multitarget-directed ligands against Alzheimer's disease.
    Yang HL, Cai P, Liu QH, Yang XL, Fang SQ, Tang YW, Wang C, Wang XB, Kong LY.
    Bioorg Med Chem; 2017 Nov 01; 25(21):5917-5928. PubMed ID: 28988627
    [Abstract] [Full Text] [Related]

  • 8. Multipotent cholinesterase/monoamine oxidase inhibitors for the treatment of Alzheimer's disease: design, synthesis, biochemical evaluation, ADMET, molecular modeling, and QSAR analysis of novel donepezil-pyridyl hybrids.
    Bautista-Aguilera OM, Esteban G, Chioua M, Nikolic K, Agbaba D, Moraleda I, Iriepa I, Soriano E, Samadi A, Unzeta M, Marco-Contelles J.
    Drug Des Devel Ther; 2014 Nov 01; 8():1893-910. PubMed ID: 25378907
    [Abstract] [Full Text] [Related]

  • 9. Development of chalcone-O-alkylamine derivatives as multifunctional agents against Alzheimer's disease.
    Bai P, Wang K, Zhang P, Shi J, Cheng X, Zhang Q, Zheng C, Cheng Y, Yang J, Lu X, Sang Z.
    Eur J Med Chem; 2019 Dec 01; 183():111737. PubMed ID: 31581002
    [Abstract] [Full Text] [Related]

  • 10. Design, synthesis, in-silico and biological evaluation of novel chalcone-O-carbamate derivatives as multifunctional agents for the treatment of Alzheimer's disease.
    Sang Z, Wang K, Shi J, Liu W, Tan Z.
    Eur J Med Chem; 2019 Sep 15; 178():726-739. PubMed ID: 31229875
    [Abstract] [Full Text] [Related]

  • 11. Synthesis and pharmacological evaluation of donepezil-based agents as new cholinesterase/monoamine oxidase inhibitors for the potential application against Alzheimer's disease.
    Li F, Wang ZM, Wu JJ, Wang J, Xie SS, Lan JS, Xu W, Kong LY, Wang XB.
    J Enzyme Inhib Med Chem; 2016 Sep 15; 31(sup3):41-53. PubMed ID: 27384289
    [Abstract] [Full Text] [Related]

  • 12. Design, synthesis and evaluation of novel tacrine-(β-carboline) hybrids as multifunctional agents for the treatment of Alzheimer's disease.
    Lan JS, Xie SS, Li SY, Pan LF, Wang XB, Kong LY.
    Bioorg Med Chem; 2014 Nov 01; 22(21):6089-104. PubMed ID: 25282654
    [Abstract] [Full Text] [Related]

  • 13. Design, synthesis and evaluation of novel ferulic acid-O-alkylamine derivatives as potential multifunctional agents for the treatment of Alzheimer's disease.
    Sang Z, Pan W, Wang K, Ma Q, Yu L, Yang Y, Bai P, Leng C, Xu Q, Li X, Tan Z, Liu W.
    Eur J Med Chem; 2017 Apr 21; 130():379-392. PubMed ID: 28279845
    [Abstract] [Full Text] [Related]

  • 14. Multifunctional tacrine-trolox hybrids for the treatment of Alzheimer's disease with cholinergic, antioxidant, neuroprotective and hepatoprotective properties.
    Xie SS, Lan JS, Wang XB, Jiang N, Dong G, Li ZR, Wang KD, Guo PP, Kong LY.
    Eur J Med Chem; 2015 Mar 26; 93():42-50. PubMed ID: 25656088
    [Abstract] [Full Text] [Related]

  • 15. Synthesis and evaluation of 7-substituted coumarin derivatives as multimodal monoamine oxidase-B and cholinesterase inhibitors for the treatment of Alzheimer's disease.
    Joubert J, Foka GB, Repsold BP, Oliver DW, Kapp E, Malan SF.
    Eur J Med Chem; 2017 Jan 05; 125():853-864. PubMed ID: 27744252
    [Abstract] [Full Text] [Related]

  • 16. N-alkylpiperidine carbamates as potential anti-Alzheimer's agents.
    Košak U, Strašek N, Knez D, Jukič M, Žakelj S, Zahirović A, Pišlar A, Brazzolotto X, Nachon F, Kos J, Gobec S.
    Eur J Med Chem; 2020 Jul 01; 197():112282. PubMed ID: 32380361
    [Abstract] [Full Text] [Related]

  • 17. Multifunctional coumarin derivatives: monoamine oxidase B (MAO-B) inhibition, anti-β-amyloid (Aβ) aggregation and metal chelation properties against Alzheimer's disease.
    Huang M, Xie SS, Jiang N, Lan JS, Kong LY, Wang XB.
    Bioorg Med Chem Lett; 2015 Feb 01; 25(3):508-13. PubMed ID: 25542589
    [Abstract] [Full Text] [Related]

  • 18. Novel 3-benzylidene/benzylphthalide Mannich base derivatives as potential multifunctional agents for the treatment of Alzheimer's disease.
    Cao Z, Song Q, Yu G, Liu Z, Cong S, Tan Z, Deng Y.
    Bioorg Med Chem; 2021 Apr 01; 35():116074. PubMed ID: 33640707
    [Abstract] [Full Text] [Related]

  • 19. Multifunctional scutellarin-rivastigmine hybrids with cholinergic, antioxidant, biometal chelating and neuroprotective properties for the treatment of Alzheimer's disease.
    Sang Z, Li Y, Qiang X, Xiao G, Liu Q, Tan Z, Deng Y.
    Bioorg Med Chem; 2015 Feb 15; 23(4):668-80. PubMed ID: 25614117
    [Abstract] [Full Text] [Related]

  • 20. From anti-Parkinson's drug rasagiline to novel multitarget iron chelators with acetylcholinesterase and monoamine oxidase inhibitory and neuroprotective properties for Alzheimer's disease.
    Zheng H, Amit T, Bar-Am O, Fridkin M, Youdim MB, Mandel SA.
    J Alzheimers Dis; 2012 Feb 15; 30(1):1-16. PubMed ID: 22387411
    [Abstract] [Full Text] [Related]

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