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PUBMED FOR HANDHELDS

Journal Abstract Search

418 related items for PubMed ID: 28814238

  • 1. Structural Insights for Drugs Developed for Phospholipase D Enzymes.
    Stieglitz KA.
    Curr Drug Discov Technol; 2018; 15(2):81-93. PubMed ID: 28814238
    [Abstract] [Full Text] [Related]

  • 2. Discovery of desketoraloxifene analogues as inhibitors of mammalian, Pseudomonas aeruginosa, and NAPE phospholipase D enzymes.
    Scott SA, Spencer CT, O'Reilly MC, Brown KA, Lavieri RR, Cho CH, Jung DI, Larock RC, Brown HA, Lindsley CW.
    ACS Chem Biol; 2015 Feb 20; 10(2):421-32. PubMed ID: 25384256
    [Abstract] [Full Text] [Related]

  • 3. Two sites of action for PLD2 inhibitors: The enzyme catalytic center and an allosteric, phosphoinositide biding pocket.
    Ganesan R, Mahankali M, Alter G, Gomez-Cambronero J.
    Biochim Biophys Acta; 2015 Mar 20; 1851(3):261-72. PubMed ID: 25532944
    [Abstract] [Full Text] [Related]

  • 4. Structure and regulation of human phospholipase D.
    Bowling FZ, Frohman MA, Airola MV.
    Adv Biol Regul; 2021 Jan 20; 79():100783. PubMed ID: 33495125
    [Abstract] [Full Text] [Related]

  • 5. Further evaluation of novel structural modifications to scaffolds that engender PLD isoform selective inhibition.
    O'Reilly MC, Scott SA, Brown HA, Lindsley CW.
    Bioorg Med Chem Lett; 2014 Dec 15; 24(24):5553-5557. PubMed ID: 25466173
    [Abstract] [Full Text] [Related]

  • 6. The phospholipase D inhibitor FIPI potently blocks EGF-induced calcium signaling in human breast cancer cells.
    Stricker HM, Rommerswinkel N, Keil S, Gnoth SA, Niggemann B, Dittmar T.
    Cell Commun Signal; 2021 Apr 08; 19(1):43. PubMed ID: 33832505
    [Abstract] [Full Text] [Related]

  • 7. 5-Fluoro-2-indolyl des-chlorohalopemide (FIPI), a phospholipase D pharmacological inhibitor that alters cell spreading and inhibits chemotaxis.
    Su W, Yeku O, Olepu S, Genna A, Park JS, Ren H, Du G, Gelb MH, Morris AJ, Frohman MA.
    Mol Pharmacol; 2009 Mar 08; 75(3):437-46. PubMed ID: 19064628
    [Abstract] [Full Text] [Related]

  • 8. 1,3-disubstituted-4-aminopyrazolo [3, 4-d] pyrimidines, a new class of potent inhibitors for phospholipase D.
    Kulkarni A, Quang P, Curry V, Keyes R, Zhou W, Cho H, Baffoe J, Török B, Stieglitz K.
    Chem Biol Drug Des; 2014 Sep 08; 84(3):270-81. PubMed ID: 24641677
    [Abstract] [Full Text] [Related]

  • 9. Phospholipase D and the Mitogen Phosphatidic Acid in Human Disease: Inhibitors of PLD at the Crossroads of Phospholipid Biology and Cancer.
    Gomez-Cambronero J, Shah KN.
    Handb Exp Pharmacol; 2020 Sep 08; 259():89-113. PubMed ID: 31541319
    [Abstract] [Full Text] [Related]

  • 10. Overexpression of phospholipase D suppresses taxotere-induced cell death in stomach cancer cells.
    Cho JH, Hong SK, Kim EY, Park SY, Park CH, Kim JM, Kwon OJ, Kwon SJ, Lee KS, Han JS.
    Biochim Biophys Acta; 2008 May 08; 1783(5):912-23. PubMed ID: 18190795
    [Abstract] [Full Text] [Related]

  • 11. Identifying New Drug Targets for Potent Phospholipase D Inhibitors: Combining Sequence Alignment, Molecular Docking, and Enzyme Activity/Binding Assays.
    Djakpa H, Kulkarni A, Barrows-Murphy S, Miller G, Zhou W, Cho H, Török B, Stieglitz K.
    Chem Biol Drug Des; 2016 May 08; 87(5):714-29. PubMed ID: 26691755
    [Abstract] [Full Text] [Related]

  • 12. Role of phospholipases D1 and 2 in astroglial proliferation: effects of specific inhibitors and genetic deletion.
    Burkhardt U, Beyer S, Klein J.
    Eur J Pharmacol; 2015 Aug 15; 761():398-404. PubMed ID: 25967349
    [Abstract] [Full Text] [Related]

  • 13. Regulation of phospholipase D activity and phosphatidic acid production after purinergic (P2Y6) receptor stimulation.
    Scott SA, Xiang Y, Mathews TP, Cho HP, Myers DS, Armstrong MD, Tallman KA, O'Reilly MC, Lindsley CW, Brown HA.
    J Biol Chem; 2013 Jul 12; 288(28):20477-87. PubMed ID: 23723068
    [Abstract] [Full Text] [Related]

  • 14. Potent direct inhibition of mammalian phospholipase D isoenzymes by calphostin-c.
    Sciorra VA, Hammond SM, Morris AJ.
    Biochemistry; 2001 Feb 27; 40(8):2640-6. PubMed ID: 11327888
    [Abstract] [Full Text] [Related]

  • 15. Design, synthesis, and biological evaluation of halogenated N-(2-(4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]decan-8-yl)ethyl)benzamides: discovery of an isoform-selective small molecule phospholipase D2 inhibitor.
    Lavieri RR, Scott SA, Selvy PE, Kim K, Jadhav S, Morrison RD, Daniels JS, Brown HA, Lindsley CW.
    J Med Chem; 2010 Sep 23; 53(18):6706-19. PubMed ID: 20735042
    [Abstract] [Full Text] [Related]

  • 16. [Phospholipase D in mammalian cells: structure, properties, physiological and pathological role].
    Szumiło M, Rahden-Staroń I.
    Postepy Hig Med Dosw (Online); 2006 Sep 23; 60():421-30. PubMed ID: 16921342
    [Abstract] [Full Text] [Related]

  • 17. Determination of the formation rate of phosphatidylethanol by phospholipase D (PLD) in blood and test of two selective PLD inhibitors.
    Schröck A, Henzi A, Bütikofer P, König S, Weinmann W.
    Alcohol; 2018 Dec 23; 73():1-7. PubMed ID: 30103144
    [Abstract] [Full Text] [Related]

  • 18. Phospholipase D inhibitors screening: Probing and evaluation of ancient and novel molecules.
    Arhab Y, Bessaa K, Abla H, Aydin M, Rahier R, Comte A, Brizuela L, Mebarek S, Perret F, Cherrier MV, Abousalham A, Noiriel A.
    Int J Biol Macromol; 2021 Jan 01; 166():1131-1140. PubMed ID: 33161081
    [Abstract] [Full Text] [Related]

  • 19. Autoregulation of phospholipase D activity is coupled to selective induction of phospholipase D1 expression to promote invasion of breast cancer cells.
    Kang DW, Park MH, Lee YJ, Kim HS, Lindsley CW, Alex Brown H, Min do S.
    Int J Cancer; 2011 Feb 15; 128(4):805-16. PubMed ID: 20473892
    [Abstract] [Full Text] [Related]

  • 20. Design and synthesis of isoform-selective phospholipase D (PLD) inhibitors. Part II. Identification of the 1,3,8-triazaspiro[4,5]decan-4-one privileged structure that engenders PLD2 selectivity.
    Lavieri R, Scott SA, Lewis JA, Selvy PE, Armstrong MD, Alex Brown H, Lindsley CW.
    Bioorg Med Chem Lett; 2009 Apr 15; 19(8):2240-3. PubMed ID: 19299128
    [Abstract] [Full Text] [Related]

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