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538 related items for PubMed ID: 28844978

  • 1. Evaluation of proline analogs as trypanocidal agents through the inhibition of a Trypanosoma cruzi proline transporter.
    Sayé M, Fargnoli L, Reigada C, Labadie GR, Pereira CA.
    Biochim Biophys Acta Gen Subj; 2017 Nov; 1861(11 Pt A):2913-2921. PubMed ID: 28844978
    [Abstract] [Full Text] [Related]

  • 2. Crystal violet structural analogues identified by in silico drug repositioning present anti-Trypanosoma cruzi activity through inhibition of proline transporter TcAAAP069.
    Sayé M, Gauna L, Valera-Vera E, Reigada C, Miranda MR, Pereira CA.
    PLoS Negl Trop Dis; 2020 Jan; 14(1):e0007481. PubMed ID: 31961864
    [Abstract] [Full Text] [Related]

  • 3. Proline modulates the Trypanosoma cruzi resistance to reactive oxygen species and drugs through a novel D, L-proline transporter.
    Sayé M, Miranda MR, di Girolamo F, de los Milagros Cámara M, Pereira CA.
    PLoS One; 2014 Jan; 9(3):e92028. PubMed ID: 24637744
    [Abstract] [Full Text] [Related]

  • 4. Trypanosoma cruzi Proline Transport Presents a Cell Density-dependent Regulation.
    Sayé M, Miranda MR, Reigada C, Pereira CA.
    J Eukaryot Microbiol; 2016 Jul; 63(4):516-23. PubMed ID: 26750517
    [Abstract] [Full Text] [Related]

  • 5. Trypanocidal Effect of Isotretinoin through the Inhibition of Polyamine and Amino Acid Transporters in Trypanosoma cruzi.
    Reigada C, Valera-Vera EA, Sayé M, Errasti AE, Avila CC, Miranda MR, Pereira CA.
    PLoS Negl Trop Dis; 2017 Mar; 11(3):e0005472. PubMed ID: 28306713
    [Abstract] [Full Text] [Related]

  • 6. Amino Acid and Polyamine Membrane Transporters in Trypanosoma cruzi: Biological Function and Evaluation as Drug Targets.
    Sayé M, Reigada C, Gauna L, Valera-Vera EA, Pereira CA, Miranda MR.
    Curr Med Chem; 2019 Mar; 26(36):6636-6651. PubMed ID: 31218951
    [Abstract] [Full Text] [Related]

  • 7. Structural design, synthesis and pharmacological evaluation of thiazoles against Trypanosoma cruzi.
    de Oliveira Filho GB, Cardoso MVO, Espíndola JWP, Oliveira E Silva DA, Ferreira RS, Coelho PL, Anjos PSD, Santos ES, Meira CS, Moreira DRM, Soares MBP, Leite ACL.
    Eur J Med Chem; 2017 Dec 01; 141():346-361. PubMed ID: 29031078
    [Abstract] [Full Text] [Related]

  • 8. Targeting polyamine transport in Trypanosoma cruzi.
    Reigada C, Phanstiel O, Miranda MR, Pereira CA.
    Eur J Med Chem; 2018 Mar 10; 147():1-6. PubMed ID: 29421567
    [Abstract] [Full Text] [Related]

  • 9. Anti-Trypanosoma cruzi activity of nicotinamide.
    Soares MB, Silva CV, Bastos TM, Guimarães ET, Figueira CP, Smirlis D, Azevedo WF.
    Acta Trop; 2012 May 10; 122(2):224-9. PubMed ID: 22281243
    [Abstract] [Full Text] [Related]

  • 10. Toxic effects of natural piperine and its derivatives on epimastigotes and amastigotes of Trypanosoma cruzi.
    Ribeiro TS, Freire-de-Lima L, Previato JO, Mendonça-Previato L, Heise N, de Lima ME.
    Bioorg Med Chem Lett; 2004 Jul 05; 14(13):3555-8. PubMed ID: 15177472
    [Abstract] [Full Text] [Related]

  • 11. Pentamidine antagonizes the benznidazole's effect in vitro, and lacks of synergy in vivo: Implications about the polyamine transport as an anti-Trypanosoma cruzi target.
    Seguel V, Castro L, Reigada C, Cortes L, Díaz MV, Miranda MR, Pereira CA, Lapier M, Campos-Estrada C, Morello A, Kemmerling U, Maya JD, López-Muñoz R.
    Exp Parasitol; 2016 Dec 05; 171():23-32. PubMed ID: 27729250
    [Abstract] [Full Text] [Related]

  • 12. Improving the drug-likeness of inspiring natural products - evaluation of the antiparasitic activity against Trypanosoma cruzi through semi-synthetic and simplified analogues of licarin A.
    Morais TR, Conserva GAA, Varela MT, Costa-Silva TA, Thevenard F, Ponci V, Fortuna A, Falcão AC, Tempone AG, Fernandes JPS, Lago JHG.
    Sci Rep; 2020 Mar 25; 10(1):5467. PubMed ID: 32214193
    [Abstract] [Full Text] [Related]

  • 13. Discovery of Strong 3-Nitro-2-Phenyl-2H-Chromene Analogues as Antitrypanosomal Agents and Inhibitors of Trypanosoma cruzi Glucokinase.
    Carey SM, O'Neill DM, Conner GB, Sherman J, Rodriguez A, D'Antonio EL.
    Int J Mol Sci; 2024 Apr 13; 25(8):. PubMed ID: 38673904
    [Abstract] [Full Text] [Related]

  • 14. Interactions between 4-aminoquinoline and heme: Promising mechanism against Trypanosoma cruzi.
    Lechuga GC, Borges JC, Calvet CM, de Araújo HP, Zuma AA, do Nascimento SB, Motta MCM, Bernardino AMR, Pereira MCS, Bourguignon SC.
    Int J Parasitol Drugs Drug Resist; 2016 Dec 13; 6(3):154-164. PubMed ID: 27490082
    [Abstract] [Full Text] [Related]

  • 15. Experimental models in Chagas disease: a review of the methodologies applied for screening compounds against Trypanosoma cruzi.
    Fonseca-Berzal C, Arán VJ, Escario JA, Gómez-Barrio A.
    Parasitol Res; 2018 Nov 13; 117(11):3367-3380. PubMed ID: 30232605
    [Abstract] [Full Text] [Related]

  • 16. Comparative effects of histone deacetylases inhibitors and resveratrol on Trypanosoma cruzi replication, differentiation, infectivity and gene expression.
    Campo VA.
    Int J Parasitol Drugs Drug Resist; 2017 Apr 13; 7(1):23-33. PubMed ID: 28038431
    [Abstract] [Full Text] [Related]

  • 17. Effect of capsaicin on the protozoan parasite Trypanosoma cruzi.
    Valera-Vera EA, Reigada C, Sayé M, Digirolamo FA, Galceran F, Miranda MR, Pereira CA.
    FEMS Microbiol Lett; 2020 Dec 22; 367(23):. PubMed ID: 33232444
    [Abstract] [Full Text] [Related]

  • 18. Design, synthesis and evaluation of novel uracil amino acid conjugates for the inhibition of Trypanosoma cruzi dUTPase.
    Mc Carthy OK, Schipani A, Buendía AM, Ruiz-Perez LM, Kaiser M, Brun R, Pacanowska DG, Gilbert IH.
    Bioorg Med Chem Lett; 2006 Jul 15; 16(14):3809-12. PubMed ID: 16677813
    [Abstract] [Full Text] [Related]

  • 19. Inhibition of NAD+-dependent histone deacetylases (sirtuins) causes growth arrest and activates both apoptosis and autophagy in the pathogenic protozoan Trypanosoma cruzi.
    Veiga-Santos P, Reignault LC, Huber K, Bracher F, De Souza W, De Carvalho TM.
    Parasitology; 2014 May 15; 141(6):814-25. PubMed ID: 24670415
    [Abstract] [Full Text] [Related]

  • 20. Investigating the structure-activity relationships of N'-[(5-nitrofuran-2-yl) methylene] substituted hydrazides against Trypanosoma cruzi to design novel active compounds.
    Palace-Berl F, Pasqualoto KFM, Zingales B, Moraes CB, Bury M, Franco CH, da Silva Neto AL, Murayama JS, Nunes SL, Silva MN, Tavares LC.
    Eur J Med Chem; 2018 Jan 20; 144():29-40. PubMed ID: 29247858
    [Abstract] [Full Text] [Related]

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