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Journal Abstract Search

255 related items for PubMed ID: 28846380

  • 1.
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  • 2. Receptor, Ligand and Transducer Contributions to Dopamine D2 Receptor Functional Selectivity.
    Peterson SM, Pack TF, Caron MG.
    PLoS One; 2015; 10(10):e0141637. PubMed ID: 26516769
    [Abstract] [Full Text] [Related]

  • 3. Elucidation of G-protein and β-arrestin functional selectivity at the dopamine D2 receptor.
    Peterson SM, Pack TF, Wilkins AD, Urs NM, Urban DJ, Bass CE, Lichtarge O, Caron MG.
    Proc Natl Acad Sci U S A; 2015 Jun 02; 112(22):7097-102. PubMed ID: 25964346
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  • 4. Distinct inactive conformations of the dopamine D2 and D3 receptors correspond to different extents of inverse agonism.
    Lane JR, Abramyan AM, Adhikari P, Keen AC, Lee KH, Sanchez J, Verma RK, Lim HD, Yano H, Javitch JA, Shi L.
    Elife; 2020 Jan 27; 9():. PubMed ID: 31985399
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  • 5. Structure-based ligand discovery targeting orthosteric and allosteric pockets of dopamine receptors.
    Lane JR, Chubukov P, Liu W, Canals M, Cherezov V, Abagyan R, Stevens RC, Katritch V.
    Mol Pharmacol; 2013 Dec 27; 84(6):794-807. PubMed ID: 24021214
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  • 6. Discovery and characterization of a G protein-biased agonist that inhibits β-arrestin recruitment to the D2 dopamine receptor.
    Free RB, Chun LS, Moritz AE, Miller BN, Doyle TB, Conroy JL, Padron A, Meade JA, Xiao J, Hu X, Dulcey AE, Han Y, Duan L, Titus S, Bryant-Genevier M, Barnaeva E, Ferrer M, Javitch JA, Beuming T, Shi L, Southall NT, Marugan JJ, Sibley DR.
    Mol Pharmacol; 2014 Jul 27; 86(1):96-105. PubMed ID: 24755247
    [Abstract] [Full Text] [Related]

  • 7. Bias analyses of preclinical and clinical D2 dopamine ligands: studies with immediate and complex signaling pathways.
    Brust TF, Hayes MP, Roman DL, Burris KD, Watts VJ.
    J Pharmacol Exp Ther; 2015 Mar 27; 352(3):480-93. PubMed ID: 25539635
    [Abstract] [Full Text] [Related]

  • 8. A QM protein-ligand investigation of antipsychotic drugs with the dopamine D2 Receptor (D2R).
    Ekhteiari Salmas R, Serhat Is Y, Durdagi S, Stein M, Yurtsever M.
    J Biomol Struct Dyn; 2018 Aug 27; 36(10):2668-2677. PubMed ID: 28805144
    [Abstract] [Full Text] [Related]

  • 9. D2 Dopamine Receptor G Protein-Biased Partial Agonists Based on Cariprazine.
    Shen Y, McCorvy JD, Martini ML, Rodriguiz RM, Pogorelov VM, Ward KM, Wetsel WC, Liu J, Roth BL, Jin J.
    J Med Chem; 2019 May 09; 62(9):4755-4771. PubMed ID: 30964661
    [Abstract] [Full Text] [Related]

  • 10. Conformation guides molecular efficacy in docking screens of activated β-2 adrenergic G protein coupled receptor.
    Weiss DR, Ahn S, Sassano MF, Kleist A, Zhu X, Strachan R, Roth BL, Lefkowitz RJ, Shoichet BK.
    ACS Chem Biol; 2013 May 17; 8(5):1018-26. PubMed ID: 23485065
    [Abstract] [Full Text] [Related]

  • 11. A single glycine in extracellular loop 1 is the critical determinant for pharmacological specificity of dopamine D2 and D3 receptors.
    Michino M, Donthamsetti P, Beuming T, Banala A, Duan L, Roux T, Han Y, Trinquet E, Newman AH, Javitch JA, Shi L.
    Mol Pharmacol; 2013 Dec 17; 84(6):854-64. PubMed ID: 24061855
    [Abstract] [Full Text] [Related]

  • 12. Ligand-optimized homology models of D₁ and D₂ dopamine receptors: application for virtual screening.
    Kołaczkowski M, Bucki A, Feder M, Pawłowski M.
    J Chem Inf Model; 2013 Mar 25; 53(3):638-48. PubMed ID: 23398329
    [Abstract] [Full Text] [Related]

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  • 15. The signaling pathway of dopamine D2 receptor (D2R) activation using normal mode analysis (NMA) and the construction of pharmacophore models for D2R ligands.
    Salmas RE, Stein M, Yurtsever M, Seeman P, Erol I, Mestanoglu M, Durdagi S.
    J Biomol Struct Dyn; 2017 Jul 25; 35(9):2040-2048. PubMed ID: 27367058
    [Abstract] [Full Text] [Related]

  • 16. The action of a negative allosteric modulator at the dopamine D2 receptor is dependent upon sodium ions.
    Draper-Joyce CJ, Verma RK, Michino M, Shonberg J, Kopinathan A, Klein Herenbrink C, Scammells PJ, Capuano B, Abramyan AM, Thal DM, Javitch JA, Christopoulos A, Shi L, Lane JR.
    Sci Rep; 2018 Jan 19; 8(1):1208. PubMed ID: 29352161
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  • 17.
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  • 18. Intramolecular allosteric communication in dopamine D2 receptor revealed by evolutionary amino acid covariation.
    Sung YM, Wilkins AD, Rodriguez GJ, Wensel TG, Lichtarge O.
    Proc Natl Acad Sci U S A; 2016 Mar 29; 113(13):3539-44. PubMed ID: 26979958
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