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Journal Abstract Search

174 related items for PubMed ID: 28864414

  • 1. Structure of 4'-demethylepipodophyllotoxin in complex with tubulin provides a rationale for drug design.
    Niu L, Wang Y, Wang C, Wang Y, Jiang X, Ma L, Wu C, Yu Y, Chen Q.
    Biochem Biophys Res Commun; 2017 Nov 04; 493(1):718-722. PubMed ID: 28864414
    [Abstract] [Full Text] [Related]

  • 2. Structure of a benzylidene derivative of 9(10H)-anthracenone in complex with tubulin provides a rationale for drug design.
    Cheng J, Wu Y, Wang Y, Wang C, Wang Y, Wu C, Zeng S, Yu Y, Chen Q.
    Biochem Biophys Res Commun; 2018 Jan 01; 495(1):185-188. PubMed ID: 29102632
    [Abstract] [Full Text] [Related]

  • 3. Structures of a diverse set of colchicine binding site inhibitors in complex with tubulin provide a rationale for drug discovery.
    Wang Y, Zhang H, Gigant B, Yu Y, Wu Y, Chen X, Lai Q, Yang Z, Chen Q, Yang J.
    FEBS J; 2016 Jan 01; 283(1):102-11. PubMed ID: 26462166
    [Abstract] [Full Text] [Related]

  • 4. Structural insights into the design of indole derivatives as tubulin polymerization inhibitors.
    Li Y, Yang J, Niu L, Hu D, Li H, Chen L, Yu Y, Chen Q.
    FEBS Lett; 2020 Jan 01; 594(1):199-204. PubMed ID: 31369682
    [Abstract] [Full Text] [Related]

  • 5. Biological evaluation and molecular modelling study of podophyllotoxin derivatives as potent inhibitors of tubulin polymerization.
    Ma Y, Fang S, Li H, Han C, Lu Y, Zhao Y, Liu Y, Zhao C.
    Chem Biol Drug Des; 2013 Jul 01; 82(1):12-21. PubMed ID: 23786349
    [Abstract] [Full Text] [Related]

  • 6. Discover 4β-NH-(6-aminoindole)-4-desoxy-podophyllotoxin with nanomolar-potency antitumor activity by improving the tubulin binding affinity on the basis of a potential binding site nearby colchicine domain.
    Zhao W, He L, Xiang TL, Tang YJ.
    Eur J Med Chem; 2019 May 15; 170():73-86. PubMed ID: 30878833
    [Abstract] [Full Text] [Related]

  • 7. A Rationale for Drug Design Provided by Co-Crystal Structure of IC261 in Complex with Tubulin.
    Xian J, Bu F, Wang Y, Long F, Zhang Z, Wu C, Tao Y, Wang T, Wang G.
    Molecules; 2021 Feb 10; 26(4):. PubMed ID: 33579052
    [Abstract] [Full Text] [Related]

  • 8. Structural Insights into the Inhibition of Tubulin by the Antitumor Agent 4β-(1,2,4-triazol-3-ylthio)-4-deoxypodophyllotoxin.
    Zhao W, Zhou C, Guan ZY, Yin P, Chen F, Tang YJ.
    ACS Chem Biol; 2017 Mar 17; 12(3):746-752. PubMed ID: 28035796
    [Abstract] [Full Text] [Related]

  • 9. Design, synthesis, biological evaluation, and 3D-QSAR analysis of podophyllotoxin-dioxazole combination as tubulin targeting anticancer agents.
    Wang ZZ, Sun WX, Wang X, Zhang YH, Qiu HY, Qi JL, Pang YJ, Lu GH, Wang XM, Yu FG, Yang YH.
    Chem Biol Drug Des; 2017 Aug 17; 90(2):236-243. PubMed ID: 28079286
    [Abstract] [Full Text] [Related]

  • 10. Molecular mechanism of crolibulin in complex with tubulin provides a rationale for drug design.
    Zhang Z, Wang C, Ma L, Jiang X, Wu C, Wang Y, Jiang Y, Zheng W, Yang Y, Ma Y, Yang J.
    Biochem Biophys Res Commun; 2019 Apr 02; 511(2):381-386. PubMed ID: 30803758
    [Abstract] [Full Text] [Related]

  • 11. Podophyllotoxin derivatives-tubulin complex reveals a potential binding site of tubulin polymerization inhibitors in α-tubulin adjacent to colchicine site.
    Zhao W, Shen R, Li HM, Zhong JJ, Tang YJ.
    Int J Biol Macromol; 2024 Sep 02; 276(Pt 1):133678. PubMed ID: 38971286
    [Abstract] [Full Text] [Related]

  • 12. Molecular modelling evaluation of the cytotoxic activity of podophyllotoxin analogues.
    Afroz Alam M, Naik PK.
    J Comput Aided Mol Des; 2009 Apr 02; 23(4):209-25. PubMed ID: 19052697
    [Abstract] [Full Text] [Related]

  • 13. Synthesis and biological evaluation of podophyllotoxin congeners as tubulin polymerization inhibitors.
    Kamal A, Srinivasa Reddy T, Polepalli S, Shalini N, Reddy VG, Subba Rao AV, Jain N, Shankaraiah N.
    Bioorg Med Chem; 2014 Oct 01; 22(19):5466-75. PubMed ID: 25131956
    [Abstract] [Full Text] [Related]

  • 14. Structural and Biochemical Characterization of the Interaction of Tubulin with Potent Natural Analogues of Podophyllotoxin.
    Antúnez-Mojica M, Rodríguez-Salarichs J, Redondo-Horcajo M, León A, Barasoain I, Canales Á, Cañada FJ, Jiménez-Barbero J, Alvarez L, Díaz JF.
    J Nat Prod; 2016 Aug 26; 79(8):2113-21. PubMed ID: 27518758
    [Abstract] [Full Text] [Related]

  • 15. A common pharmacophore for a diverse set of colchicine site inhibitors using a structure-based approach.
    Nguyen TL, McGrath C, Hermone AR, Burnett JC, Zaharevitz DW, Day BW, Wipf P, Hamel E, Gussio R.
    J Med Chem; 2005 Sep 22; 48(19):6107-16. PubMed ID: 16162011
    [Abstract] [Full Text] [Related]

  • 16. Design and biological evaluation of novel tubulin inhibitors as antimitotic agents using a pharmacophore binding model with tubulin.
    Kim DY, Kim KH, Kim ND, Lee KY, Han CK, Yoon JH, Moon SK, Lee SS, Seong BL.
    J Med Chem; 2006 Sep 21; 49(19):5664-70. PubMed ID: 16970393
    [Abstract] [Full Text] [Related]

  • 17. Tubulin inhibitors targeting the colchicine binding site: a perspective of privileged structures.
    Li W, Sun H, Xu S, Zhu Z, Xu J.
    Future Med Chem; 2017 Oct 21; 9(15):1765-1794. PubMed ID: 28929799
    [Abstract] [Full Text] [Related]

  • 18. Identification of potent virtual leads and ADME prediction of isoxazolidine podophyllotoxin derivatives as topoisomerase II and tubulin inhibitors.
    Bkhaitan MM, Mirza AZ, Shamshad H, Ali HI.
    J Mol Graph Model; 2017 May 21; 73():74-93. PubMed ID: 28242581
    [Abstract] [Full Text] [Related]

  • 19. Recent advances in research of colchicine binding site inhibitors and their interaction modes with tubulin.
    Sun K, Sun Z, Zhao F, Shan G, Meng Q.
    Future Med Chem; 2021 May 21; 13(9):839-858. PubMed ID: 33821673
    [Abstract] [Full Text] [Related]

  • 20. Antileishmanial activity and tubulin polymerization inhibition of podophyllotoxin derivatives on Leishmania infantum.
    Escudero-Martínez JM, Pérez-Pertejo Y, Reguera RM, Castro MÁ, Rojo MV, Santiago C, Abad A, García PA, López-Pérez JL, San Feliciano A, Balaña-Fouce R.
    Int J Parasitol Drugs Drug Resist; 2017 Dec 21; 7(3):272-285. PubMed ID: 28719882
    [Abstract] [Full Text] [Related]

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