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Journal Abstract Search

844 related items for PubMed ID: 28865292

  • 1. Pyrazole-hydrazone derivatives as anti-inflammatory agents: Design, synthesis, biological evaluation, COX-1,2/5-LOX inhibition and docking study.
    Abdelgawad MA, Labib MB, Abdel-Latif M.
    Bioorg Chem; 2017 Oct; 74():212-220. PubMed ID: 28865292
    [Abstract] [Full Text] [Related]

  • 2. New hybrid molecules combining benzothiophene or benzofuran with rhodanine as dual COX-1/2 and 5-LOX inhibitors: Synthesis, biological evaluation and docking study.
    El-Miligy MMM, Hazzaa AA, El-Messmary H, Nassra RA, El-Hawash SAM.
    Bioorg Chem; 2017 Jun; 72():102-115. PubMed ID: 28390993
    [Abstract] [Full Text] [Related]

  • 3. Novel N-substituted 5-aminosalicylamides as dual inhibitors of cyclooxygenase and 5-lipoxygenase enzymes: Synthesis, biological evaluation and docking study.
    El-Nagar MKS, Abdu-Allah HHM, Salem OIA, Kafafy AN, Farghaly HSM.
    Bioorg Chem; 2018 Aug; 78():80-93. PubMed ID: 29550533
    [Abstract] [Full Text] [Related]

  • 4. Benzodioxole-Pyrazole Hybrids as Anti-Inflammatory and Analgesic Agents with COX-1,2/5-LOX Inhibition and Antioxidant Potential.
    Abd El Razik HA, Badr MH, Atta AH, Mouneir SM, Abu-Serie MM.
    Arch Pharm (Weinheim); 2017 May; 350(5):. PubMed ID: 28418202
    [Abstract] [Full Text] [Related]

  • 5. Synthesis, anti-inflammatory screening, molecular docking, and COX-1,2/-5-LOX inhibition profile of some novel quinoline derivatives.
    Chaaban I, Rizk OH, Ibrahim TM, Henen SS, El-Khawass EM, Bayad AE, El-Ashmawy IM, Nematalla HA.
    Bioorg Chem; 2018 Aug; 78():220-235. PubMed ID: 29602046
    [Abstract] [Full Text] [Related]

  • 6. New benzothiophene derivatives as dual COX-1/2 and 5-LOX inhibitors: synthesis, biological evaluation and docking study.
    El-Miligy MM, Hazzaa AA, El-Messmary H, Nassra RA, El-Hawash SA.
    Future Med Chem; 2017 Apr; 9(5):443-468. PubMed ID: 28362117
    [Abstract] [Full Text] [Related]

  • 7. Novel click modifiable thioquinazolinones as anti-inflammatory agents: Design, synthesis, biological evaluation and docking study.
    Moussa G, Alaaeddine R, Alaeddine LM, Nassra R, Belal ASF, Ismail A, El-Yazbi AF, Abdel-Ghany YS, Hazzaa A.
    Eur J Med Chem; 2018 Jan 20; 144():635-650. PubMed ID: 29289887
    [Abstract] [Full Text] [Related]

  • 8. Design, synthesis, biological evaluation and docking study of novel indole-2-amide as anti-inflammatory agents with dual inhibition of COX and 5-LOX.
    Huang Y, Zhang B, Li J, Liu H, Zhang Y, Yang Z, Liu W.
    Eur J Med Chem; 2019 Oct 15; 180():41-50. PubMed ID: 31299586
    [Abstract] [Full Text] [Related]

  • 9. Design, synthesis, and biological evaluation of novel 1,2-diaryl-4-substituted-benzylidene-5(4H)-imidazolone derivatives as cytotoxic agents and COX-2/LOX inhibitors.
    Lamie PF, Philoppes JN, Rárová L.
    Arch Pharm (Weinheim); 2018 Apr 15; 351(3-4):e1700311. PubMed ID: 29400411
    [Abstract] [Full Text] [Related]

  • 10. Design, synthesis, and biological evaluation of some novel indolizine derivatives as dual cyclooxygenase and lipoxygenase inhibitor for anti-inflammatory activity.
    Shrivastava SK, Srivastava P, Bandresh R, Tripathi PN, Tripathi A.
    Bioorg Med Chem; 2017 Aug 15; 25(16):4424-4432. PubMed ID: 28669741
    [Abstract] [Full Text] [Related]

  • 11. New pyrazole derivatives: Synthesis, anti-inflammatory activity, cycloxygenase inhibition assay and evaluation of mPGES.
    Hassan GS, Abdel Rahman DE, Abdelmajeed EA, Refaey RH, Alaraby Salem M, Nissan YM.
    Eur J Med Chem; 2019 Jun 01; 171():332-342. PubMed ID: 30928706
    [Abstract] [Full Text] [Related]

  • 12. 1,3,4-Trisubstituted pyrazole analogues as promising anti-inflammatory agents.
    Alegaon SG, Alagawadi KR, Garg MK, Dushyant K, Vinod D.
    Bioorg Chem; 2014 Jun 01; 54():51-9. PubMed ID: 24793214
    [Abstract] [Full Text] [Related]

  • 13. Cyclooxygenase-2 and 15-lipoxygenase inhibition, synthesis, anti-inflammatory activity and ulcer liability of new celecoxib analogues: Determination of region-specific pyrazole ring formation by NOESY.
    Abdelall EKA, Lamie PF, Ali WAM.
    Bioorg Med Chem Lett; 2016 Jun 15; 26(12):2893-2899. PubMed ID: 27158139
    [Abstract] [Full Text] [Related]

  • 14. Synthesis, biological evaluation and molecular modeling study of pyrazole derivatives as selective COX-2 inhibitors and anti-inflammatory agents.
    Tewari AK, Singh VP, Yadav P, Gupta G, Singh A, Goel RK, Shinde P, Mohan CG.
    Bioorg Chem; 2014 Oct 15; 56():8-15. PubMed ID: 24893208
    [Abstract] [Full Text] [Related]

  • 15. Synthesis and structure-activity relationship studies of 1,3-diarylprop-2-yn-1-ones: dual inhibitors of cyclooxygenases and lipoxygenases.
    Rao PN, Chen QH, Knaus EE.
    J Med Chem; 2006 Mar 09; 49(5):1668-83. PubMed ID: 16509583
    [Abstract] [Full Text] [Related]

  • 16. 1,4-Dihydroquinazolin-3(2H)-yl benzamide derivatives as anti-inflammatory and analgesic agents with an improved gastric profile: Design, synthesis, COX-1/2 inhibitory activity and molecular docking study.
    Sakr A, Kothayer H, Ibrahim SM, Baraka MM, Rezq S.
    Bioorg Chem; 2019 Mar 09; 84():76-86. PubMed ID: 30481648
    [Abstract] [Full Text] [Related]

  • 17. Discovery of new 2-(3-(naphthalen-2-yl)-4,5-dihydro-1H-pyrazol-1-yl)thiazole derivatives with potential analgesic and anti-inflammatory activities: In vitro, in vivo and in silico investigations.
    Mohammed ER, Abd-El-Fatah AH, Mohamed AR, Mahrouse MA, Mohammad MA.
    Bioorg Chem; 2024 Jun 09; 147():107372. PubMed ID: 38653152
    [Abstract] [Full Text] [Related]

  • 18. Design, synthesis, analgesic, anti-inflammatory activity of novel pyrazolones possessing aminosulfonyl pharmacophore as inhibitors of COX-2/5-LOX enzymes: Histopathological and docking studies.
    Abdelgawad MA, Labib MB, Ali WAM, Kamel G, Azouz AA, El-Nahass ES.
    Bioorg Chem; 2018 Aug 09; 78():103-114. PubMed ID: 29550530
    [Abstract] [Full Text] [Related]

  • 19. Design, synthesis and mechanistic study of novel diarylpyrazole derivatives as anti-inflammatory agents with reduced cardiovascular side effects.
    Amin NH, Hamed MIA, Abdel-Fattah MM, Abusabaa AHA, El-Saadi MT.
    Bioorg Chem; 2021 Nov 09; 116():105394. PubMed ID: 34619468
    [Abstract] [Full Text] [Related]

  • 20. Synthesis and biological evaluation of pyrazolone analogues as potential anti-inflammatory agents targeting cyclooxygenases and 5-lipoxygenase.
    Shabaan MA, Kamal AM, Faggal SI, Elsahar AE, Mohamed KO.
    Arch Pharm (Weinheim); 2020 Apr 09; 353(4):e1900308. PubMed ID: 32031284
    [Abstract] [Full Text] [Related]

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