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Journal Abstract Search

449 related items for PubMed ID: 28881253

  • 1. 5-Substituted 2-benzylidene-1-tetralone analogues as A1 and/or A2A antagonists for the potential treatment of neurological conditions.
    Janse van Rensburg HD, Terre'Blanche G, van der Walt MM, Legoabe LJ.
    Bioorg Chem; 2017 Oct; 74():251-259. PubMed ID: 28881253
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  • 2. Evaluation of 2-benzylidene-1-tetralone derivatives as antagonists of A1 and A2A adenosine receptors.
    Legoabe LJ, Van der Walt MM, Terre'Blanche G.
    Chem Biol Drug Des; 2018 Jan; 91(1):234-244. PubMed ID: 28734058
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  • 3. 2-Benzylidene-1-Indanone Analogues as Dual Adenosine A1/A2a Receptor Antagonists for the Potential Treatment of Neurological Conditions.
    van Rensburg HJ, Legoabe L, Terre'Blanche G, Van der Walt M.
    Drug Res (Stuttg); 2019 Jul; 69(7):382-391. PubMed ID: 30616250
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  • 4. C2-substituted quinazolinone derivatives exhibit A1 and/or A2A adenosine receptor affinities in the low micromolar range.
    Pieterse L, van der Walt MM, Terre'Blanche G.
    Bioorg Med Chem Lett; 2020 Aug 15; 30(16):127274. PubMed ID: 32631506
    [Abstract] [Full Text] [Related]

  • 5. Discovery of 1,3-diethyl-7-methyl-8-(phenoxymethyl)-xanthine derivatives as novel adenosine A1 and A2A receptor antagonists.
    Harmse R, van der Walt MM, Petzer JP, Terre'Blanche G.
    Bioorg Med Chem Lett; 2016 Dec 15; 26(24):5951-5955. PubMed ID: 27836398
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  • 6. Synthesis and evaluation of methoxy substituted 2-benzoyl-1-benzofuran derivatives as lead compounds for the development adenosine A1 and/or A2A receptor antagonists.
    Janse van Rensburg HD, Legoabe LJ, Terre'Blanche G, Aucamp J.
    Bioorg Chem; 2020 Jan 15; 94():103459. PubMed ID: 31818481
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  • 7. Imidazo[1,2-α]pyridines possess adenosine A1 receptor affinity for the potential treatment of cognition in neurological disorders.
    Lefin R, van der Walt MM, Milne PJ, Terre'Blanche G.
    Bioorg Med Chem Lett; 2017 Sep 01; 27(17):3963-3967. PubMed ID: 28789895
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  • 9. 1,3,7-Triethyl-substituted xanthines--possess nanomolar affinity for the adenosine A1 receptor.
    Van der Walt MM, Terre'Blanche G.
    Bioorg Med Chem; 2015 Oct 15; 23(20):6641-9. PubMed ID: 26392370
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  • 10. Synthesis and Structure Activity Relationships of Chalcone based Benzocycloalkanone Derivatives as Adenosine A1 and/or A2A Receptor Antagonists.
    Janse van Rensburg HD, Legoabe LJ, Terre'Blanche G.
    Drug Res (Stuttg); 2020 Jun 15; 70(6):243-256. PubMed ID: 32349128
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  • 12. 2-Aminopyrimidines as dual adenosine A1/A2A antagonists.
    Robinson SJ, Petzer JP, Terre'Blanche G, Petzer A, van der Walt MM, Bergh JJ, Lourens AC.
    Eur J Med Chem; 2015 Nov 02; 104():177-88. PubMed ID: 26462195
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  • 14. JNJ-40255293, a novel adenosine A2A/A1 antagonist with efficacy in preclinical models of Parkinson's disease.
    Atack JR, Shook BC, Rassnick S, Jackson PF, Rhodes K, Drinkenburg WH, Ahnaou A, Te Riele P, Langlois X, Hrupka B, De Haes P, Hendrickx H, Aerts N, Hens K, Wellens A, Vermeire J, Megens AA.
    ACS Chem Neurosci; 2014 Oct 15; 5(10):1005-19. PubMed ID: 25203719
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  • 15. Identification of novel thiazolo[5,4-d]pyrimidine derivatives as human A1 and A2A adenosine receptor antagonists/inverse agonists.
    Varano F, Catarzi D, Falsini M, Vincenzi F, Pasquini S, Varani K, Colotta V.
    Bioorg Med Chem; 2018 Jul 23; 26(12):3688-3695. PubMed ID: 29880250
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  • 17. Selected C8 two-chain linkers enhance the adenosine A1/A2A receptor affinity and selectivity of caffeine.
    van der Walt MM, Terre'Blanche G.
    Eur J Med Chem; 2017 Jan 05; 125():652-656. PubMed ID: 27721150
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