These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
2. Evidence that glutamic acid 49 of tryptophan synthase alpha subunit is a catalytic residue. Inactive mutant proteins substituted at position 49 bind ligands and transmit ligand-dependent to the beta subunit. Miles EW, McPhie P, Yutani K. J Biol Chem; 1988 Jun 25; 263(18):8611-4. PubMed ID: 2897961 [Abstract] [Full Text] [Related]
6. Site-directed mutagenesis of the alpha subunit of tryptophan synthase from Salmonella typhimurium. Ahmed SA, Kawasaki H, Bauerle R, Morita H, Miles EW. Biochem Biophys Res Commun; 1988 Mar 15; 151(2):672-8. PubMed ID: 3126743 [Abstract] [Full Text] [Related]
10. Site-specific mutagenesis of the alpha subunit of tryptophan synthase from Salmonella typhimurium. Changing arginine 179 to leucine alters the reciprocal transmission of substrate-induced conformational changes between the alpha and beta 2 subunits. Kawasaki H, Bauerle R, Zon G, Ahmed SA, Miles EW. J Biol Chem; 1987 Aug 05; 262(22):10678-83. PubMed ID: 3112150 [Abstract] [Full Text] [Related]
16. Ligand-mediated changes in the tryptophan synthase indole tunnel probed by nile red fluorescence with wild type, mutant, and chemically modified enzymes. Ruvinov SB, Yang XJ, Parris KD, Banik U, Ahmed SA, Miles EW, Sackett DL. J Biol Chem; 1995 Mar 17; 270(11):6357-69. PubMed ID: 7890774 [Abstract] [Full Text] [Related]
20. The tryptophan synthase bienzyme complex transfers indole between the alpha- and beta-sites via a 25-30 A long tunnel. Dunn MF, Aguilar V, Brzović P, Drewe WF, Houben KF, Leja CA, Roy M. Biochemistry; 1990 Sep 18; 29(37):8598-607. PubMed ID: 2271543 [Abstract] [Full Text] [Related] Page: [Next] [New Search]