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Journal Abstract Search
403 related items for PubMed ID: 28919339
1. Novel xanthone-polyamine conjugates as catalytic inhibitors of human topoisomerase IIα. Minniti E, Byl JAW, Riccardi L, Sissi C, Rosini M, De Vivo M, Minarini A, Osheroff N. Bioorg Med Chem Lett; 2017 Oct 15; 27(20):4687-4693. PubMed ID: 28919339 [Abstract] [Full Text] [Related]
2. Synthesis and biological evaluation of C1-O-substituted-3-(3-butylamino-2-hydroxy-propoxy)-xanthen-9-one as topoisomerase IIα catalytic inhibitors. Park S, Hong E, Kwak SY, Jun KY, Lee ES, Kwon Y, Na Y. Eur J Med Chem; 2016 Nov 10; 123():211-225. PubMed ID: 27484510 [Abstract] [Full Text] [Related]
3. Synthesis, biological evaluation, and molecular docking study of 3-(3'-heteroatom substituted-2'-hydroxy-1'-propyloxy) xanthone analogues as novel topoisomerase IIα catalytic inhibitor. Jun KY, Lee EY, Jung MJ, Lee OH, Lee ES, Park Choo HY, Na Y, Kwon Y. Eur J Med Chem; 2011 Jun 10; 46(6):1964-71. PubMed ID: 21419530 [Abstract] [Full Text] [Related]
4. 3-(3-Butylamino-2-hydroxy-propoxy)-1-hydroxy-xanthen-9-one acts as a topoisomerase IIα catalytic inhibitor with low DNA damage. Park SE, Chang IH, Jun KY, Lee E, Lee ES, Na Y, Kwon Y. Eur J Med Chem; 2013 Nov 10; 69():139-45. PubMed ID: 24013413 [Abstract] [Full Text] [Related]
5. N-fused imidazoles as novel anticancer agents that inhibit catalytic activity of topoisomerase IIα and induce apoptosis in G1/S phase. Baviskar AT, Madaan C, Preet R, Mohapatra P, Jain V, Agarwal A, Guchhait SK, Kundu CN, Banerjee UC, Bharatam PV. J Med Chem; 2011 Jul 28; 54(14):5013-30. PubMed ID: 21644529 [Abstract] [Full Text] [Related]
6. Inhibition of human DNA topoisomerase IIα by two novel ellipticine derivatives. Vann KR, Ergün Y, Zencir S, Oncuoglu S, Osheroff N, Topcu Z. Bioorg Med Chem Lett; 2016 Apr 01; 26(7):1809-12. PubMed ID: 26906637 [Abstract] [Full Text] [Related]
7. 4,6-Substituted-1,3,5-triazin-2(1H)-ones as monocyclic catalytic inhibitors of human DNA topoisomerase IIα targeting the ATP binding site. Pogorelčnik B, Janežič M, Sosič I, Gobec S, Solmajer T, Perdih A. Bioorg Med Chem; 2015 Aug 01; 23(15):4218-4229. PubMed ID: 26183545 [Abstract] [Full Text] [Related]
9. Novel trifluoromethylated 9-amino-3,4-dihydroacridin-1(2H)-ones act as covalent poisons of human topoisomerase IIα. Infante Lara L, Sledge A, Laradji A, Okoro CO, Osheroff N. Bioorg Med Chem Lett; 2017 Feb 01; 27(3):586-589. PubMed ID: 27998679 [Abstract] [Full Text] [Related]
11. HU-331 is a catalytic inhibitor of topoisomerase IIα. Regal KM, Mercer SL, Deweese JE. Chem Res Toxicol; 2014 Dec 15; 27(12):2044-51. PubMed ID: 25409338 [Abstract] [Full Text] [Related]
12. Monocyclic 4-amino-6-(phenylamino)-1,3,5-triazines as inhibitors of human DNA topoisomerase IIα. Pogorelčnik B, Brvar M, Zajc I, Filipič M, Solmajer T, Perdih A. Bioorg Med Chem Lett; 2014 Dec 15; 24(24):5762-5768. PubMed ID: 25453816 [Abstract] [Full Text] [Related]
13. Gambogic acid inhibits the catalytic activity of human topoisomerase IIalpha by binding to its ATPase domain. Qin Y, Meng L, Hu C, Duan W, Zuo Z, Lin L, Zhang X, Ding J. Mol Cancer Ther; 2007 Sep 15; 6(9):2429-40. PubMed ID: 17876042 [Abstract] [Full Text] [Related]
14. Synthesis of friedelan triterpenoid analogs with DNA topoisomerase IIα inhibitory activity and their molecular docking studies. Mandal A, Ghosh S, Bothra AK, Nanda AK, Ghosh P. Eur J Med Chem; 2012 Aug 15; 54():137-43. PubMed ID: 22633831 [Abstract] [Full Text] [Related]
15. Structure-guided optimization of 4,6-substituted-1,3,5-triazin-2(1H)-ones as catalytic inhibitors of human DNA topoisomerase IIα. Bergant K, Janežič M, Valjavec K, Sosič I, Pajk S, Štampar M, Žegura B, Gobec S, Filipič M, Perdih A. Eur J Med Chem; 2019 Aug 01; 175():330-348. PubMed ID: 31096154 [Abstract] [Full Text] [Related]
16. Recent advances in the development of catalytic inhibitors of human DNA topoisomerase IIα as novel anticancer agents. Pogorelčnik B, Perdih A, Solmajer T. Curr Med Chem; 2013 Aug 01; 20(5):694-709. PubMed ID: 23210851 [Abstract] [Full Text] [Related]