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Journal Abstract Search

482 related items for PubMed ID: 28931885

  • 1. Design, synthesis and structure-activity relationship of 3,6-diaryl-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazines as novel tubulin inhibitors.
    Xu Q, Bao K, Sun M, Xu J, Wang Y, Tian H, Zuo D, Guan Q, Wu Y, Zhang W.
    Sci Rep; 2017 Sep 20; 7(1):11997. PubMed ID: 28931885
    [Abstract] [Full Text] [Related]

  • 2. Design and discovery of new antiproliferative 1,2,4-triazin-3(2H)-ones as tubulin polymerization inhibitors targeting colchicine binding site.
    Eissa IH, Dahab MA, Ibrahim MK, Alsaif NA, Alanazi AZ, Eissa SI, Mehany ABM, Beauchemin AM.
    Bioorg Chem; 2021 Jul 20; 112():104965. PubMed ID: 34020238
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  • 3. Design, synthesis and bioevaluation of 2,7-diaryl-pyrazolo[1,5-a]pyrimidines as tubulin polymerization inhibitors.
    Liu R, Zhang S, Huang M, Guo Z, Li L, Li M, Wu L, Guan Q, Zhang W.
    Bioorg Chem; 2021 Oct 20; 115():105220. PubMed ID: 34352709
    [Abstract] [Full Text] [Related]

  • 4. Design, synthesis and bioevaluation of antitubulin agents carrying diaryl-5,5-fused-heterocycle scaffold.
    Xu Q, Sun M, Bai Z, Wang Y, Wu Y, Tian H, Zuo D, Guan Q, Bao K, Wu Y, Zhang W.
    Eur J Med Chem; 2017 Oct 20; 139():242-249. PubMed ID: 28802124
    [Abstract] [Full Text] [Related]

  • 5. 3-(3-Methoxyphenyl)-6-(3-amino-4-methoxyphenyl)-7H-[1,2,4] triazolo [3,4-b][1,3,4] thiadiazine, a novel tubulin inhibitor, evokes G2/M cell cycle arrest and apoptosis in SGC-7901 and HeLa cells.
    Liu Z, Lang B, Gao M, Chang X, Guan Q, Xu Q, Wu D, Li Z, Zuo D, Zhang W, Wu Y.
    J Cell Biochem; 2020 Mar 20; 121(3):2184-2196. PubMed ID: 31642107
    [Abstract] [Full Text] [Related]

  • 6. Novel [1,2,4]triazolo[1,5-a]pyrimidine derivatives as potent antitubulin agents: Design, multicomponent synthesis and antiproliferative activities.
    Yang F, Yu LZ, Diao PC, Jian XE, Zhou MF, Jiang CS, You WW, Ma WF, Zhao PL.
    Bioorg Chem; 2019 Nov 20; 92():103260. PubMed ID: 31525523
    [Abstract] [Full Text] [Related]

  • 7. (E)-N-Aryl-2-oxo-2-(3,4,5-trimethoxyphenyl)acetohydrazonoyl cyanides as tubulin polymerization inhibitors: Structure-based bioisosterism design, synthesis, biological evaluation, molecular docking and in silico ADME prediction.
    Wang G, Peng Z, Peng S, Qiu J, Li Y, Lan Y.
    Bioorg Med Chem Lett; 2018 Nov 01; 28(20):3350-3355. PubMed ID: 30197030
    [Abstract] [Full Text] [Related]

  • 8. Synthesis and Bioevaluation of 3,6-Diaryl-[1,2,4]triazolo[4,3-b] Pyridazines as Antitubulin Agents.
    Xu Q, Wang Y, Xu J, Sun M, Tian H, Zuo D, Guan Q, Bao K, Wu Y, Zhang W.
    ACS Med Chem Lett; 2016 Dec 08; 7(12):1202-1206. PubMed ID: 27994764
    [Abstract] [Full Text] [Related]

  • 9. Synthesis and bioevaluation of N,4-diaryl-1,3-thiazole-2-amines as tubulin inhibitors with potent antiproliferative activity.
    Sun M, Xu Q, Xu J, Wu Y, Wang Y, Zuo D, Guan Q, Bao K, Wang J, Wu Y, Zhang W.
    PLoS One; 2017 Dec 08; 12(3):e0174006. PubMed ID: 28333984
    [Abstract] [Full Text] [Related]

  • 10. Design, synthesis, biological evaluation and molecular docking studies of new chalcone derivatives containing diaryl ether moiety as potential anticancer agents and tubulin polymerization inhibitors.
    Wang G, Liu W, Gong Z, Huang Y, Li Y, Peng Z.
    Bioorg Chem; 2020 Jan 08; 95():103565. PubMed ID: 31927336
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  • 14. Design, synthesis and bio-evaluation of novel 2-aryl-4-(3,4,5-trimethoxy-benzoyl)-5-substituted-1,2,3-triazoles as the tubulin polymerization inhibitors.
    Huang L, Liu M, Man S, Ma D, Feng D, Sun Z, Guan Q, Zuo D, Wu Y, Zhang W, Bao K.
    Eur J Med Chem; 2020 Jan 15; 186():111846. PubMed ID: 31740055
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  • 20. Discovery of novel 6-p-tolyl-3-(3,4,5-trimethoxybenzyl)-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazine derivative as a potent tubulin inhibitor with promising in vivo antitumor activity.
    Ji T, Jian X, Chen L, Zeng W, Huo X, Li M, Chen P, Zhang Y, You W, Zhao P.
    Eur J Med Chem; 2023 Aug 05; 256():115437. PubMed ID: 37172475
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