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Journal Abstract Search

196 related items for PubMed ID: 28952073

  • 1. Cysteine to Serine Conversion at 111th Position Renders the Disaggregation and Retains the Stabilization of Detrimental SOD1 A4V Mutant Against Amyotrophic Lateral Sclerosis in Human-A Discrete Molecular Dynamics Study.
    Srinivasan E, Rajasekaran R.
    Cell Biochem Biophys; 2018 Jun; 76(1-2):231-241. PubMed ID: 28952073
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  • 2. Alterations in local stability and dynamics of A4V SOD1 in the presence of trifluoroethanol.
    Kumar V, Prakash A, Lynn AM.
    Biopolymers; 2018 Mar; 109(3):e23102. PubMed ID: 29369331
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  • 3. Molecular binding response of naringin and naringenin to H46R mutant SOD1 protein in combating protein aggregation using density functional theory and discrete molecular dynamics.
    Srinivasan E, Rajasekaran R.
    Prog Biophys Mol Biol; 2019 Aug; 145():40-51. PubMed ID: 30543828
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  • 5. A Phosphomimetic Mutation Stabilizes SOD1 and Rescues Cell Viability in the Context of an ALS-Associated Mutation.
    Fay JM, Zhu C, Proctor EA, Tao Y, Cui W, Ke H, Dokholyan NV.
    Structure; 2016 Nov 01; 24(11):1898-1906. PubMed ID: 27667694
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  • 8. Computational Investigation on Electrostatic Loop Mutants Instigating Destabilization and Aggregation on Human SOD1 Protein Causing Amyotrophic Lateral Sclerosis.
    Srinivasan E, Rajasekaran R.
    Protein J; 2019 Feb 01; 38(1):37-49. PubMed ID: 30701485
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  • 9. SOD1 in amyotrophic lateral sclerosis development - in silico analysis and molecular dynamics of A4F and A4V variants.
    Da Silva ANR, Pereira GRC, Moreira LGA, Rocha CF, De Mesquita JF.
    J Cell Biochem; 2019 Oct 01; 120(10):17822-17830. PubMed ID: 31134679
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  • 11. Probing the inhibitory activity of epigallocatechin-gallate on toxic aggregates of mutant (L84F) SOD1 protein through geometry based sampling and steered molecular dynamics.
    Srinivasan E, Rajasekaran R.
    J Mol Graph Model; 2017 Jun 01; 74():288-295. PubMed ID: 28458007
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  • 12. Characterization of the activity, aggregation, and toxicity of heterodimers of WT and ALS-associated mutant Sod1.
    Brasil AA, de Carvalho MDC, Gerhardt E, Queiroz DD, Pereira MD, Outeiro TF, Eleutherio ECA.
    Proc Natl Acad Sci U S A; 2019 Dec 17; 116(51):25991-26000. PubMed ID: 31796595
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  • 14. Comparative binding of kaempferol and kaempferide on inhibiting the aggregate formation of mutant (G85R) SOD1 protein in familial amyotrophic lateral sclerosis: A quantum chemical and molecular mechanics study.
    Srinivasan E, Rajasekaran R.
    Biofactors; 2018 Sep 17; 44(5):431-442. PubMed ID: 30260512
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  • 16. Probing the polyphenolic flavonoid, morin as a highly efficacious inhibitor against amyloid(A4V) mutant SOD1 in fatal amyotrophic lateral sclerosis.
    Srinivasan E, Chandrasekhar G, Rajasekaran R.
    Arch Biochem Biophys; 2022 Sep 30; 727():109318. PubMed ID: 35690129
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  • 17. ALS-linked mutant SOD1 proteins promote Aβ aggregates in ALS through direct interaction with Aβ.
    Jang JY, Cho H, Park HY, Rhim H, Kang S.
    Biochem Biophys Res Commun; 2017 Nov 04; 493(1):697-707. PubMed ID: 28864422
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  • 18. Polyanion binding accelerates the formation of stable and low-toxic aggregates of ALS-linked SOD1 mutant A4V.
    Zhao D, Zhang S, Meng Y, Xiongwei D, Zhang D, Liang Y, Wang L, Liu C.
    Proteins; 2014 Dec 04; 82(12):3356-72. PubMed ID: 25220364
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  • 19. Perspective on SOD1 mediated toxicity in Amyotrophic Lateral Sclerosis.
    Sangwan S, Eisenberg DS.
    Postepy Biochem; 2016 Dec 04; 62(3):362-369. PubMed ID: 28132491
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  • 20. Large SOD1 aggregates, unlike trimeric SOD1, do not impact cell viability in a model of amyotrophic lateral sclerosis.
    Zhu C, Beck MV, Griffith JD, Deshmukh M, Dokholyan NV.
    Proc Natl Acad Sci U S A; 2018 May 01; 115(18):4661-4665. PubMed ID: 29666246
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