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233 related items for PubMed ID: 28964787

  • 1. Negative regulation of Sirtuin 1 by AMP-activated protein kinase promotes metformin-induced senescence in hepatocellular carcinoma xenografts.
    Zhou X, Chen J, Chen L, Feng X, Liu Z, Hu L, Zeng Z, Jia X, Liang M, Shi B, Yi G, Liu J.
    Cancer Lett; 2017 Dec 28; 411():1-11. PubMed ID: 28964787
    [Abstract] [Full Text] [Related]

  • 2. Regulation of SIRT1/AMPK axis is critically involved in gallotannin-induced senescence and impaired autophagy leading to cell death in hepatocellular carcinoma cells.
    Kwon HY, Kim JH, Kim B, Srivastava SK, Kim SH.
    Arch Toxicol; 2018 Jan 28; 92(1):241-257. PubMed ID: 28676953
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  • 4. PCK1 negatively regulates cell cycle progression and hepatoma cell proliferation via the AMPK/p27Kip1 axis.
    Tuo L, Xiang J, Pan X, Hu J, Tang H, Liang L, Xia J, Hu Y, Zhang W, Huang A, Wang K, Tang N.
    J Exp Clin Cancer Res; 2019 Feb 04; 38(1):50. PubMed ID: 30717766
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  • 5. Prognostic significance of AMPK activation and therapeutic effects of metformin in hepatocellular carcinoma.
    Zheng L, Yang W, Wu F, Wang C, Yu L, Tang L, Qiu B, Li Y, Guo L, Wu M, Feng G, Zou D, Wang H.
    Clin Cancer Res; 2013 Oct 01; 19(19):5372-80. PubMed ID: 23942093
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  • 6. Aspirin Targets SIRT1 and AMPK to Induce Senescence of Colorectal Carcinoma Cells.
    Jung YR, Kim EJ, Choi HJ, Park JJ, Kim HS, Lee YJ, Park MJ, Lee M.
    Mol Pharmacol; 2015 Oct 01; 88(4):708-19. PubMed ID: 26219912
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  • 7. Metformin suppresses hypoxia-induced stabilization of HIF-1α through reprogramming of oxygen metabolism in hepatocellular carcinoma.
    Zhou X, Chen J, Yi G, Deng M, Liu H, Liang M, Shi B, Fu X, Chen Y, Chen L, He Z, Wang J, Liu J.
    Oncotarget; 2016 Jan 05; 7(1):873-84. PubMed ID: 26621849
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  • 8. Nilotinib induces autophagy in hepatocellular carcinoma through AMPK activation.
    Yu HC, Lin CS, Tai WT, Liu CY, Shiau CW, Chen KF.
    J Biol Chem; 2013 Jun 21; 288(25):18249-59. PubMed ID: 23677989
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  • 9. AMP-activated protein kinase suppresses the in vitro and in vivo proliferation of hepatocellular carcinoma.
    Cheng J, Huang T, Li Y, Guo Y, Zhu Y, Wang Q, Tan X, Chen W, Zhang Y, Cheng W, Yamamoto T, Jing X, Huang J.
    PLoS One; 2014 Jun 21; 9(4):e93256. PubMed ID: 24709998
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  • 10. Metformin regulates mitochondrial biogenesis and senescence through AMPK mediated H3K79 methylation: Relevance in age-associated vascular dysfunction.
    Karnewar S, Neeli PK, Panuganti D, Kotagiri S, Mallappa S, Jain N, Jerald MK, Kotamraju S.
    Biochim Biophys Acta Mol Basis Dis; 2018 Apr 21; 1864(4 Pt A):1115-1128. PubMed ID: 29366775
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  • 11. Hemistepsin A Inhibits Cell Proliferation and Induces G0/G1-Phase Arrest, Cellular Senescence and Apoptosis Via the AMPK and p53/p21 Signals in Human Hepatocellular Carcinoma.
    Baek SY, Hwang UW, Suk HY, Kim YW.
    Biomolecules; 2020 May 04; 10(5):. PubMed ID: 32375410
    [Abstract] [Full Text] [Related]

  • 12. Simvastatin-induced cell cycle arrest through inhibition of STAT3/SKP2 axis and activation of AMPK to promote p27 and p21 accumulation in hepatocellular carcinoma cells.
    Wang ST, Ho HJ, Lin JT, Shieh JJ, Wu CY.
    Cell Death Dis; 2017 Feb 23; 8(2):e2626. PubMed ID: 28230855
    [Abstract] [Full Text] [Related]

  • 13. Metformin sensitizes sorafenib to inhibit postoperative recurrence and metastasis of hepatocellular carcinoma in orthotopic mouse models.
    You A, Cao M, Guo Z, Zuo B, Gao J, Zhou H, Li H, Cui Y, Fang F, Zhang W, Song T, Li Q, Zhu X, Yin H, Sun H, Zhang T.
    J Hematol Oncol; 2016 Mar 08; 9():20. PubMed ID: 26957312
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  • 14. Metformin and AICAR regulate NANOG expression via the JNK pathway in HepG2 cells independently of AMPK.
    Shen C, Ka SO, Kim SJ, Kim JH, Park BH, Park JH.
    Tumour Biol; 2016 Aug 08; 37(8):11199-208. PubMed ID: 26939902
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  • 15. Activation of the AMPK/Sirt1 pathway by a leucine-metformin combination increases insulin sensitivity in skeletal muscle, and stimulates glucose and lipid metabolism and increases life span in Caenorhabditis elegans.
    Banerjee J, Bruckbauer A, Zemel MB.
    Metabolism; 2016 Nov 08; 65(11):1679-1691. PubMed ID: 27456392
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  • 16. AMPK inhibits MTDH expression via GSK3β and SIRT1 activation: potential role in triple negative breast cancer cell proliferation.
    Gollavilli PN, Kanugula AK, Koyyada R, Karnewar S, Neeli PK, Kotamraju S.
    FEBS J; 2015 Oct 08; 282(20):3971-85. PubMed ID: 26236947
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  • 17. SIRT1 promotes proliferation and prevents senescence through targeting LKB1 in primary porcine aortic endothelial cells.
    Zu Y, Liu L, Lee MY, Xu C, Liang Y, Man RY, Vanhoutte PM, Wang Y.
    Circ Res; 2010 Apr 30; 106(8):1384-93. PubMed ID: 20203304
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