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PUBMED FOR HANDHELDS

Journal Abstract Search


289 related items for PubMed ID: 28974242

  • 1. Oleate ameliorates palmitate-induced reduction of NAMPT activity and NAD levels in primary human hepatocytes and hepatocarcinoma cells.
    Penke M, Schuster S, Gorski T, Gebhardt R, Kiess W, Garten A.
    Lipids Health Dis; 2017 Oct 03; 16(1):191. PubMed ID: 28974242
    [Abstract] [Full Text] [Related]

  • 2. Inhibition of NAMPT aggravates high fat diet-induced hepatic steatosis in mice through regulating Sirt1/AMPKα/SREBP1 signaling pathway.
    Wang LF, Wang XN, Huang CC, Hu L, Xiao YF, Guan XH, Qian YS, Deng KY, Xin HB.
    Lipids Health Dis; 2017 Apr 27; 16(1):82. PubMed ID: 28449683
    [Abstract] [Full Text] [Related]

  • 3. FK866-induced NAMPT inhibition activates AMPK and downregulates mTOR signaling in hepatocarcinoma cells.
    Schuster S, Penke M, Gorski T, Gebhardt R, Weiss TS, Kiess W, Garten A.
    Biochem Biophys Res Commun; 2015 Mar 06; 458(2):334-40. PubMed ID: 25656579
    [Abstract] [Full Text] [Related]

  • 4. NAMPT inhibitor and metabolite protect mouse brain from cryoinjury through distinct mechanisms.
    Zhang XQ, Lu JT, Jiang WX, Lu YB, Wu M, Wei EQ, Zhang WP, Tang C.
    Neuroscience; 2015 Apr 16; 291():230-40. PubMed ID: 25684751
    [Abstract] [Full Text] [Related]

  • 5. CD73 protein as a source of extracellular precursors for sustained NAD+ biosynthesis in FK866-treated tumor cells.
    Grozio A, Sociali G, Sturla L, Caffa I, Soncini D, Salis A, Raffaelli N, De Flora A, Nencioni A, Bruzzone S.
    J Biol Chem; 2013 Sep 06; 288(36):25938-25949. PubMed ID: 23880765
    [Abstract] [Full Text] [Related]

  • 6. Inhibition of Nicotinamide Phosphoribosyltransferase (NAMPT), an Enzyme Essential for NAD+ Biosynthesis, Leads to Altered Carbohydrate Metabolism in Cancer Cells.
    Tan B, Dong S, Shepard RL, Kays L, Roth KD, Geeganage S, Kuo MS, Zhao G.
    J Biol Chem; 2015 Jun 19; 290(25):15812-15824. PubMed ID: 25944913
    [Abstract] [Full Text] [Related]

  • 7. NAMPT protects against 6-hydroxydopamine-induced neurotoxicity in PC12 cells through modulating SIRT1 activity.
    Zou XD, Guo SQ, Hu ZW, Li WL.
    Mol Med Rep; 2016 May 19; 13(5):4058-64. PubMed ID: 27035562
    [Abstract] [Full Text] [Related]

  • 8. Targeting NAD+ salvage pathway induces autophagy in multiple myeloma cells via mTORC1 and extracellular signal-regulated kinase (ERK1/2) inhibition.
    Cea M, Cagnetta A, Fulciniti M, Tai YT, Hideshima T, Chauhan D, Roccaro A, Sacco A, Calimeri T, Cottini F, Jakubikova J, Kong SY, Patrone F, Nencioni A, Gobbi M, Richardson P, Munshi N, Anderson KC.
    Blood; 2012 Oct 25; 120(17):3519-29. PubMed ID: 22955917
    [Abstract] [Full Text] [Related]

  • 9. Regulation of the Nampt-mediated NAD salvage pathway and its therapeutic implications in pancreatic cancer.
    Ju HQ, Zhuang ZN, Li H, Tian T, Lu YX, Fan XQ, Zhou HJ, Mo HY, Sheng H, Chiao PJ, Xu RH.
    Cancer Lett; 2016 Aug 28; 379(1):1-11. PubMed ID: 27233476
    [Abstract] [Full Text] [Related]

  • 10. Antitumor effect of combined NAMPT and CD73 inhibition in an ovarian cancer model.
    Sociali G, Raffaghello L, Magnone M, Zamporlini F, Emionite L, Sturla L, Bianchi G, Vigliarolo T, Nahimana A, Nencioni A, Raffaelli N, Bruzzone S.
    Oncotarget; 2016 Jan 19; 7(3):2968-84. PubMed ID: 26658104
    [Abstract] [Full Text] [Related]

  • 11. Resveratrol differentially regulates NAMPT and SIRT1 in Hepatocarcinoma cells and primary human hepatocytes.
    Schuster S, Penke M, Gorski T, Petzold-Quinque S, Damm G, Gebhardt R, Kiess W, Garten A.
    PLoS One; 2014 Jan 19; 9(3):e91045. PubMed ID: 24603648
    [Abstract] [Full Text] [Related]

  • 12. Oleate rescues INS-1E β-cells from palmitate-induced apoptosis by preventing activation of the unfolded protein response.
    Sommerweiss D, Gorski T, Richter S, Garten A, Kiess W.
    Biochem Biophys Res Commun; 2013 Nov 29; 441(4):770-6. PubMed ID: 24189472
    [Abstract] [Full Text] [Related]

  • 13. Targeting the NAD+ salvage pathway suppresses APC mutation-driven colorectal cancer growth and Wnt/β-catenin signaling via increasing Axin level.
    Ye C, Qi L, Li X, Wang J, Yu J, Zhou B, Guo C, Chen J, Zheng S.
    Cell Commun Signal; 2020 Jan 31; 18(1):16. PubMed ID: 32005247
    [Abstract] [Full Text] [Related]

  • 14. NAMPT pathway is involved in the FOXO3a-mediated regulation of GADD45A expression.
    Thakur BK, Lippka Y, Dittrich T, Chandra P, Skokowa J, Welte K.
    Biochem Biophys Res Commun; 2012 Apr 20; 420(4):714-20. PubMed ID: 22430142
    [Abstract] [Full Text] [Related]

  • 15. FK866 compromises mitochondrial metabolism and adaptive stress responses in cultured cardiomyocytes.
    Oyarzún AP, Westermeier F, Pennanen C, López-Crisosto C, Parra V, Sotomayor-Flores C, Sánchez G, Pedrozo Z, Troncoso R, Lavandero S.
    Biochem Pharmacol; 2015 Nov 01; 98(1):92-101. PubMed ID: 26297909
    [Abstract] [Full Text] [Related]

  • 16. NAMPT Overexpression Drives Cell Growth in Polycystic Liver Disease through Mitochondrial Metabolism Regulation.
    Pant K, Gradilone SA.
    Am J Pathol; 2024 Aug 01; 194(8):1528-1537. PubMed ID: 38849029
    [Abstract] [Full Text] [Related]

  • 17. Inhibition of nicotinamide phosphoribosyltransferase and depletion of nicotinamide adenine dinucleotide contribute to arsenic trioxide suppression of oral squamous cell carcinoma.
    Wang XY, Wang JZ, Gao L, Zhang FY, Wang Q, Liu KJ, Xiang B.
    Toxicol Appl Pharmacol; 2017 Sep 15; 331():54-61. PubMed ID: 28501332
    [Abstract] [Full Text] [Related]

  • 18. Loss of NAMPT in aging retinal pigment epithelium reduces NAD+ availability and promotes cellular senescence.
    Jadeja RN, Powell FL, Jones MA, Fuller J, Joseph E, Thounaojam MC, Bartoli M, Martin PM.
    Aging (Albany NY); 2018 Jun 12; 10(6):1306-1323. PubMed ID: 29905535
    [Abstract] [Full Text] [Related]

  • 19. EWS-FLI1 confers exquisite sensitivity to NAMPT inhibition in Ewing sarcoma cells.
    Mutz CN, Schwentner R, Aryee DNT, Bouchard EDJ, Mejia EM, Hatch GM, Kauer MO, Katschnig AM, Ban J, Garten A, Alonso J, Banerji V, Kovar H.
    Oncotarget; 2017 Apr 11; 8(15):24679-24693. PubMed ID: 28160567
    [Abstract] [Full Text] [Related]

  • 20. Nicotinamide phosphoribosyltransferase: a potent therapeutic target in non-small cell lung cancer with epidermal growth factor receptor-gene mutation.
    Okumura S, Sasaki T, Minami Y, Ohsaki Y.
    J Thorac Oncol; 2012 Jan 11; 7(1):49-56. PubMed ID: 22089115
    [Abstract] [Full Text] [Related]


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