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1420 related items for PubMed ID: 29031078

  • 1. Structural design, synthesis and pharmacological evaluation of thiazoles against Trypanosoma cruzi.
    de Oliveira Filho GB, Cardoso MVO, Espíndola JWP, Oliveira E Silva DA, Ferreira RS, Coelho PL, Anjos PSD, Santos ES, Meira CS, Moreira DRM, Soares MBP, Leite ACL.
    Eur J Med Chem; 2017 Dec 01; 141():346-361. PubMed ID: 29031078
    [Abstract] [Full Text] [Related]

  • 2. Desing and synthesis of potent anti-Trypanosoma cruzi agents new thiazoles derivatives which induce apoptotic parasite death.
    da Silva EB, Oliveira E Silva DA, Oliveira AR, da Silva Mendes CH, Dos Santos TA, da Silva AC, de Castro MC, Ferreira RS, Moreira DR, Cardoso MV, de Simone CA, Pereira VR, Leite AC.
    Eur J Med Chem; 2017 Apr 21; 130():39-50. PubMed ID: 28242550
    [Abstract] [Full Text] [Related]

  • 3. Conformational restriction of aryl thiosemicarbazones produces potent and selective anti-Trypanosoma cruzi compounds which induce apoptotic parasite death.
    Magalhaes Moreira DR, de Oliveira AD, Teixeira de Moraes Gomes PA, de Simone CA, Villela FS, Ferreira RS, da Silva AC, dos Santos TA, Brelaz de Castro MC, Pereira VR, Leite AC.
    Eur J Med Chem; 2014 Mar 21; 75():467-78. PubMed ID: 24561675
    [Abstract] [Full Text] [Related]

  • 4. 2-(phenylthio)ethylidene derivatives as anti-Trypanosoma cruzi compounds: Structural design, synthesis and antiparasitic activity.
    Cardoso MVO, Oliveira Filho GB, Siqueira LRP, Espíndola JWP, Silva EBD, Mendes APO, Pereira VRA, Castro MCAB, Ferreira RS, Villela FS, Costa FMRD, Meira CS, Moreira DRM, Soares MBP, Leite ACL.
    Eur J Med Chem; 2019 Oct 15; 180():191-203. PubMed ID: 31306906
    [Abstract] [Full Text] [Related]

  • 5. 2-Pyridyl thiazoles as novel anti-Trypanosoma cruzi agents: structural design, synthesis and pharmacological evaluation.
    Cardoso MV, de Siqueira LR, da Silva EB, Costa LB, Hernandes MZ, Rabello MM, Ferreira RS, da Cruz LF, Moreira DR, Pereira VR, de Castro MC, Bernhardt PV, Leite AC.
    Eur J Med Chem; 2014 Oct 30; 86():48-59. PubMed ID: 25147146
    [Abstract] [Full Text] [Related]

  • 6. Structural design, synthesis and pharmacological evaluation of 4-thiazolidinones against Trypanosoma cruzi.
    de Oliveira Filho GB, de Oliveira Cardoso MV, Espíndola JW, Ferreira LF, de Simone CA, Ferreira RS, Coelho PL, Meira CS, Magalhaes Moreira DR, Soares MB, Lima Leite AC.
    Bioorg Med Chem; 2015 Dec 01; 23(23):7478-86. PubMed ID: 26549870
    [Abstract] [Full Text] [Related]

  • 7. New 1,3-thiazole derivatives and their biological and ultrastructural effects on Trypanosoma cruzi.
    de Moraes Gomes PAT, de Oliveira Barbosa M, Farias Santiago E, de Oliveira Cardoso MV, Capistrano Costa NT, Hernandes MZ, Moreira DRM, da Silva AC, Dos Santos TAR, Pereira VRA, Brayner Dos Santosd FA, do Nascimento Pereira GA, Ferreira RS, Leite ACL.
    Eur J Med Chem; 2016 Oct 04; 121():387-398. PubMed ID: 27295485
    [Abstract] [Full Text] [Related]

  • 8. Efficacy of 2-hydroxy-3-phenylsulfanylmethyl-[1,4]-naphthoquinone derivatives against different Trypanosoma cruzi discrete type units: Identification of a promising hit compound.
    Lara LS, Moreira CS, Calvet CM, Lechuga GC, Souza RS, Bourguignon SC, Ferreira VF, Rocha D, Pereira MCS.
    Eur J Med Chem; 2018 Jan 20; 144():572-581. PubMed ID: 29289882
    [Abstract] [Full Text] [Related]

  • 9. In vitro and in vivo antiparasitic activity of Physalis angulata L. concentrated ethanolic extract against Trypanosoma cruzi.
    Meira CS, Guimarães ET, Dos Santos JA, Moreira DR, Nogueira RC, Tomassini TC, Ribeiro IM, de Souza CV, Ribeiro Dos Santos R, Soares MB.
    Phytomedicine; 2015 Oct 15; 22(11):969-74. PubMed ID: 26407938
    [Abstract] [Full Text] [Related]

  • 10. Development of bis-thiazoles as inhibitors of triosephosphate isomerase from Trypanosoma cruzi. Identification of new non-mutagenic agents that are active in vivo.
    Álvarez G, Martínez J, Varela J, Birriel E, Cruces E, Gabay M, Leal SM, Escobar P, Aguirre-López B, Cabrera N, Tuena de Gómez-Puyou M, Gómez Puyou A, Pérez-Montfort R, Yaluff G, Torres S, Serna E, Vera de Bilbao N, González M, Cerecetto H.
    Eur J Med Chem; 2015 Jul 15; 100():246-56. PubMed ID: 26094151
    [Abstract] [Full Text] [Related]

  • 11. Structural design, synthesis and structure-activity relationships of thiazolidinones with enhanced anti-Trypanosoma cruzi activity.
    Moreira DR, Leite AC, Cardoso MV, Srivastava RM, Hernandes MZ, Rabello MM, da Cruz LF, Ferreira RS, de Simone CA, Meira CS, Guimaraes ET, da Silva AC, dos Santos TA, Pereira VR, Soares MB.
    ChemMedChem; 2014 Jan 15; 9(1):177-88. PubMed ID: 24203393
    [Abstract] [Full Text] [Related]

  • 12. Dual Parasiticidal Activities of Phthalimides: Synthesis and Biological Profile against Trypanosoma cruzi and Plasmodium falciparum.
    Teixeira de Moraes Gomes PA, Veríssimo de Oliveira Cardoso M, Dos Santos IR, Amaro de Sousa F, da Conceição JM, Gouveia de Melo Silva V, Duarte D, Pereira R, Oliveira R, Nogueira F, Alves LC, Brayner FA, da Silva Santos AC, Rêgo Alves Pereira V, Lima Leite AC.
    ChemMedChem; 2020 Nov 18; 15(22):2164-2175. PubMed ID: 32813331
    [Abstract] [Full Text] [Related]

  • 13. Identification of a new amide-containing thiazole as a drug candidate for treatment of Chagas' disease.
    Álvarez G, Varela J, Cruces E, Fernández M, Gabay M, Leal SM, Escobar P, Sanabria L, Serna E, Torres S, Figueredo Thiel SJ, Yaluff G, Vera de Bilbao NI, Cerecetto H, González M.
    Antimicrob Agents Chemother; 2015 Mar 18; 59(3):1398-404. PubMed ID: 25512408
    [Abstract] [Full Text] [Related]

  • 14. Phthalimido-thiazoles as building blocks and their effects on the growth and morphology of Trypanosoma cruzi.
    Gomes PA, Oliveira AR, Cardoso MV, Santiago Ede F, Barbosa Mde O, de Siqueira LR, Moreira DR, Bastos TM, Brayner FA, Soares MB, Mendes AP, de Castro MC, Pereira VR, Leite AC.
    Eur J Med Chem; 2016 Mar 23; 111():46-57. PubMed ID: 26854377
    [Abstract] [Full Text] [Related]

  • 15. Structural design, synthesis and anti-Trypanosoma cruzi profile of the second generation of 4-thiazolidinones chlorine derivatives.
    Bezerra de Oliveira Filho G, Veríssimo de Oliveira Cardoso M, Caroline da Silva Santos A, Ramos Dos Santos TA, Cristovão-Silva AC, Rubio LG, da Silva Maia Neto L, Leite PG, Machado FS, Alves LC, Brayner FA, Alves Pereira VR, Lima Leite AC.
    Chem Biol Interact; 2021 Aug 25; 345():109514. PubMed ID: 34023282
    [Abstract] [Full Text] [Related]

  • 16. Structural investigation of anti-Trypanosoma cruzi 2-iminothiazolidin-4-ones allows the identification of agents with efficacy in infected mice.
    Moreira DR, Costa SP, Hernandes MZ, Rabello MM, de Oliveira Filho GB, de Melo CM, da Rocha LF, de Simone CA, Ferreira RS, Fradico JR, Meira CS, Guimarães ET, Srivastava RM, Pereira VR, Soares MB, Leite AC.
    J Med Chem; 2012 Dec 27; 55(24):10918-36. PubMed ID: 23167554
    [Abstract] [Full Text] [Related]

  • 17. Trypanosoma cruzi killing and immune response boosting by novel phenoxyhydrazine-thiazole against Chagas disease.
    Cristovão-Silva AC, Brelaz-de-Castro MCA, Dionisio da Silva E, Leite ACL, Santiago LBAA, Conceição JMD, da Silva Tiburcio R, de Santana DP, Bedor DCG, de Carvalho BÍV, Ferreira LFGR, de Freitas E Silva R, Alves Pereira VR, Hernandes MZ.
    Exp Parasitol; 2024 Jun 27; 261():108749. PubMed ID: 38593864
    [Abstract] [Full Text] [Related]

  • 18. Identification of Novel Functionalized Carbohydrazonamides Designed as Chagas Disease Drug Candidates.
    do Nascimento MSS, Câmara VRF, da Costa JS, Barbosa JMC, Lins ASM, Salomão K, de Castro SL, Carvalho SA, da Silva EF, Fraga CAM.
    Med Chem; 2020 Jun 27; 16(6):774-783. PubMed ID: 31244442
    [Abstract] [Full Text] [Related]

  • 19. Investigating the structure-activity relationships of N'-[(5-nitrofuran-2-yl) methylene] substituted hydrazides against Trypanosoma cruzi to design novel active compounds.
    Palace-Berl F, Pasqualoto KFM, Zingales B, Moraes CB, Bury M, Franco CH, da Silva Neto AL, Murayama JS, Nunes SL, Silva MN, Tavares LC.
    Eur J Med Chem; 2018 Jan 20; 144():29-40. PubMed ID: 29247858
    [Abstract] [Full Text] [Related]

  • 20. Synthesis, Biological Evaluation and Molecular Docking of New Benzenesulfonylhydrazone as Potential anti-Trypanosoma cruzi Agents.
    Elizondo-Jimenez S, Moreno-Herrera A, Reyes-Olivares R, Dorantes-Gonzalez E, Nogueda-Torres B, Oliveira EAG, Romeiro NC, Lima LM, Palos I, Rivera G.
    Med Chem; 2017 Jan 20; 13(2):149-158. PubMed ID: 27396731
    [Abstract] [Full Text] [Related]

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