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Journal Abstract Search

307 related items for PubMed ID: 29033317

  • 1. Ras Binder Induces a Modified Switch-II Pocket in GTP and GDP States.
    Gentile DR, Rathinaswamy MK, Jenkins ML, Moss SM, Siempelkamp BD, Renslo AR, Burke JE, Shokat KM.
    Cell Chem Biol; 2017 Dec 21; 24(12):1455-1466.e14. PubMed ID: 29033317
    [Abstract] [Full Text] [Related]

  • 2. Structural insight into the rearrangement of the switch I region in GTP-bound G12A K-Ras.
    Xu S, Long BN, Boris GH, Chen A, Ni S, Kennedy MA.
    Acta Crystallogr D Struct Biol; 2017 Dec 01; 73(Pt 12):970-984. PubMed ID: 29199977
    [Abstract] [Full Text] [Related]

  • 3. Structural basis for conformational dynamics of GTP-bound Ras protein.
    Shima F, Ijiri Y, Muraoka S, Liao J, Ye M, Araki M, Matsumoto K, Yamamoto N, Sugimoto T, Yoshikawa Y, Kumasaka T, Yamamoto M, Tamura A, Kataoka T.
    J Biol Chem; 2010 Jul 16; 285(29):22696-705. PubMed ID: 20479006
    [Abstract] [Full Text] [Related]

  • 4. GTP Binding and Oncogenic Mutations May Attenuate Hypervariable Region (HVR)-Catalytic Domain Interactions in Small GTPase K-Ras4B, Exposing the Effector Binding Site.
    Lu S, Banerjee A, Jang H, Zhang J, Gaponenko V, Nussinov R.
    J Biol Chem; 2015 Nov 27; 290(48):28887-900. PubMed ID: 26453300
    [Abstract] [Full Text] [Related]

  • 5. Comparison of ras-p21 bound to GDP and GTP: differences in protein and ligand dynamics.
    Mello LV, van Aalten DM, Findlay JB.
    Protein Eng; 1997 Apr 27; 10(4):381-7. PubMed ID: 9194162
    [Abstract] [Full Text] [Related]

  • 6. K-Ras(G12C) inhibitors allosterically control GTP affinity and effector interactions.
    Ostrem JM, Peters U, Sos ML, Wells JA, Shokat KM.
    Nature; 2013 Nov 28; 503(7477):548-51. PubMed ID: 24256730
    [Abstract] [Full Text] [Related]

  • 7. In situ selectivity profiling and crystal structure of SML-8-73-1, an active site inhibitor of oncogenic K-Ras G12C.
    Hunter JC, Gurbani D, Ficarro SB, Carrasco MA, Lim SM, Choi HG, Xie T, Marto JA, Chen Z, Gray NS, Westover KD.
    Proc Natl Acad Sci U S A; 2014 Jun 17; 111(24):8895-900. PubMed ID: 24889603
    [Abstract] [Full Text] [Related]

  • 8. Design of Small Molecules That Compete with Nucleotide Binding to an Engineered Oncogenic KRAS Allele.
    Zhang Y, Larraufie MH, Musavi L, Akkiraju H, Brown LM, Stockwell BR.
    Biochemistry; 2018 Feb 27; 57(8):1380-1389. PubMed ID: 29313669
    [Abstract] [Full Text] [Related]

  • 9. Conformational Dynamics Allows Sampling of an "Active-like" State by Oncogenic K-Ras-GDP.
    Grudzien P, Jang H, Leschinsky N, Nussinov R, Gaponenko V.
    J Mol Biol; 2022 Sep 15; 434(17):167695. PubMed ID: 35752212
    [Abstract] [Full Text] [Related]

  • 10. The higher level of complexity of K-Ras4B activation at the membrane.
    Jang H, Banerjee A, Chavan TS, Lu S, Zhang J, Gaponenko V, Nussinov R.
    FASEB J; 2016 Apr 15; 30(4):1643-55. PubMed ID: 26718888
    [Abstract] [Full Text] [Related]

  • 11. Crystal structures of Ral-GppNHp and Ral-GDP reveal two binding sites that are also present in Ras and Rap.
    Nicely NI, Kosak J, de Serrano V, Mattos C.
    Structure; 2004 Nov 15; 12(11):2025-36. PubMed ID: 15530367
    [Abstract] [Full Text] [Related]

  • 12. Conformational states of human rat sarcoma (Ras) protein complexed with its natural ligand GTP and their role for effector interaction and GTP hydrolysis.
    Spoerner M, Hozsa C, Poetzl JA, Reiss K, Ganser P, Geyer M, Kalbitzer HR.
    J Biol Chem; 2010 Dec 17; 285(51):39768-78. PubMed ID: 20937837
    [Abstract] [Full Text] [Related]

  • 13. Monitoring Ras Interactions with the Nucleotide Exchange Factor Son of Sevenless (Sos) Using Site-specific NMR Reporter Signals and Intrinsic Fluorescence.
    Vo U, Vajpai N, Flavell L, Bobby R, Breeze AL, Embrey KJ, Golovanov AP.
    J Biol Chem; 2016 Jan 22; 291(4):1703-1718. PubMed ID: 26565026
    [Abstract] [Full Text] [Related]

  • 14. Dynamic studies of H-Ras•GTPγS interactions with nucleotide exchange factor Sos reveal a transient ternary complex formation in solution.
    Vo U, Vajpai N, Embrey KJ, Golovanov AP.
    Sci Rep; 2016 Jul 14; 6():29706. PubMed ID: 27412770
    [Abstract] [Full Text] [Related]

  • 15. Raman difference studies of GDP and GTP binding to c-Harvey ras.
    Wang JH, Xiao DG, Deng H, Webb MR, Callender R.
    Biochemistry; 1998 Aug 04; 37(31):11106-16. PubMed ID: 9693007
    [Abstract] [Full Text] [Related]

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  • 17. Electrostatic control of GTP and GDP binding in the oncoprotein p21ras.
    Muegge I, Schweins T, Langen R, Warshel A.
    Structure; 1996 Apr 15; 4(4):475-89. PubMed ID: 8740369
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  • 20. Mutant-Specific Targeting of Ras G12C Activity by Covalently Reacting Small Molecules.
    Goody RS, Müller MP, Rauh D.
    Cell Chem Biol; 2019 Oct 17; 26(10):1338-1348. PubMed ID: 31378709
    [Abstract] [Full Text] [Related]

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