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366 related items for PubMed ID: 29036434

  • 1. Novel mechanisms of eIF2B action and regulation by eIF2α phosphorylation.
    Bogorad AM, Lin KY, Marintchev A.
    Nucleic Acids Res; 2017 Nov 16; 45(20):11962-11979. PubMed ID: 29036434
    [Abstract] [Full Text] [Related]

  • 2. eIF2B Mechanisms of Action and Regulation: A Thermodynamic View.
    Bogorad AM, Lin KY, Marintchev A.
    Biochemistry; 2018 Mar 06; 57(9):1426-1435. PubMed ID: 29425030
    [Abstract] [Full Text] [Related]

  • 3. eIF2B and the Integrated Stress Response: A Structural and Mechanistic View.
    Marintchev A, Ito T.
    Biochemistry; 2020 Apr 07; 59(13):1299-1308. PubMed ID: 32200625
    [Abstract] [Full Text] [Related]

  • 4. The beta/Gcd7 subunit of eukaryotic translation initiation factor 2B (eIF2B), a guanine nucleotide exchange factor, is crucial for binding eIF2 in vivo.
    Dev K, Qiu H, Dong J, Zhang F, Barthlme D, Hinnebusch AG.
    Mol Cell Biol; 2010 Nov 07; 30(21):5218-33. PubMed ID: 20805354
    [Abstract] [Full Text] [Related]

  • 5. Crystal structure of eIF2B and insights into eIF2-eIF2B interactions.
    Kashiwagi K, Ito T, Yokoyama S.
    FEBS J; 2017 Mar 07; 284(6):868-874. PubMed ID: 27627185
    [Abstract] [Full Text] [Related]

  • 6. Tight binding of the phosphorylated alpha subunit of initiation factor 2 (eIF2alpha) to the regulatory subunits of guanine nucleotide exchange factor eIF2B is required for inhibition of translation initiation.
    Krishnamoorthy T, Pavitt GD, Zhang F, Dever TE, Hinnebusch AG.
    Mol Cell Biol; 2001 Aug 07; 21(15):5018-30. PubMed ID: 11438658
    [Abstract] [Full Text] [Related]

  • 7. Fail-safe control of translation initiation by dissociation of eIF2α phosphorylated ternary complexes.
    Jennings MD, Kershaw CJ, Adomavicius T, Pavitt GD.
    Elife; 2017 Mar 18; 6():. PubMed ID: 28315520
    [Abstract] [Full Text] [Related]

  • 8. A C-term truncated EIF2Bγ protein encoded by an intronically polyadenylated isoform introduces unfavorable EIF2Bγ-EIF2γ interactions.
    Circir A, Koksal Bicakci G, Savas B, Doken DN, Henden ŞO, Can T, Karaca E, Erson-Bensan AE.
    Proteins; 2022 Mar 18; 90(3):889-897. PubMed ID: 34796993
    [Abstract] [Full Text] [Related]

  • 9. Biochemical analysis of the eIF2beta gamma complex reveals a structural function for eIF2alpha in catalyzed nucleotide exchange.
    Nika J, Rippel S, Hannig EM.
    J Biol Chem; 2001 Jan 12; 276(2):1051-6. PubMed ID: 11042214
    [Abstract] [Full Text] [Related]

  • 10. Eukaryotic initiation factor eIF2.
    Kimball SR.
    Int J Biochem Cell Biol; 1999 Jan 12; 31(1):25-9. PubMed ID: 10216940
    [Abstract] [Full Text] [Related]

  • 11. ISRIB Blunts the Integrated Stress Response by Allosterically Antagonising the Inhibitory Effect of Phosphorylated eIF2 on eIF2B.
    Zyryanova AF, Kashiwagi K, Rato C, Harding HP, Crespillo-Casado A, Perera LA, Sakamoto A, Nishimoto M, Yonemochi M, Shirouzu M, Ito T, Ron D.
    Mol Cell; 2021 Jan 07; 81(1):88-103.e6. PubMed ID: 33220178
    [Abstract] [Full Text] [Related]

  • 12. Phosphorylation of serine 51 in initiation factor 2 alpha (eIF2 alpha) promotes complex formation between eIF2 alpha(P) and eIF2B and causes inhibition in the guanine nucleotide exchange activity of eIF2B.
    Sudhakar A, Ramachandran A, Ghosh S, Hasnain SE, Kaufman RJ, Ramaiah KV.
    Biochemistry; 2000 Oct 24; 39(42):12929-38. PubMed ID: 11041858
    [Abstract] [Full Text] [Related]

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  • 15. Crystal structure of eukaryotic translation initiation factor 2B.
    Kashiwagi K, Takahashi M, Nishimoto M, Hiyama TB, Higo T, Umehara T, Sakamoto K, Ito T, Yokoyama S.
    Nature; 2016 Mar 03; 531(7592):122-5. PubMed ID: 26901872
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  • 17. An eIF5/eIF2 complex antagonizes guanine nucleotide exchange by eIF2B during translation initiation.
    Singh CR, Lee B, Udagawa T, Mohammad-Qureshi SS, Yamamoto Y, Pavitt GD, Asano K.
    EMBO J; 2006 Oct 04; 25(19):4537-46. PubMed ID: 16990799
    [Abstract] [Full Text] [Related]

  • 18. Wheat germ initiation factor 2 (WG x eIF2) decreases the inhibition in protein synthesis and eIF2B activity of reticulocyte lysates mediated by eIF2alpha phosphorylation.
    Krishna VM, Janaki N, Ramaiah KV.
    Arch Biochem Biophys; 1997 Oct 01; 346(1):28-36. PubMed ID: 9328281
    [Abstract] [Full Text] [Related]

  • 19. Identification of domains and residues within the epsilon subunit of eukaryotic translation initiation factor 2B (eIF2Bepsilon) required for guanine nucleotide exchange reveals a novel activation function promoted by eIF2B complex formation.
    Gomez E, Pavitt GD.
    Mol Cell Biol; 2000 Jun 01; 20(11):3965-76. PubMed ID: 10805739
    [Abstract] [Full Text] [Related]

  • 20. Structural basis for eIF2B inhibition in integrated stress response.
    Kashiwagi K, Yokoyama T, Nishimoto M, Takahashi M, Sakamoto A, Yonemochi M, Shirouzu M, Ito T.
    Science; 2019 May 03; 364(6439):495-499. PubMed ID: 31048492
    [Abstract] [Full Text] [Related]

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