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127 related items for PubMed ID: 29054436

  • 1. In vitro and ex vivo screening of candidate therapeutics to restore neurotransmission in nerve terminals intoxicated by botulinum neurotoxin serotype A1.
    Beske PH, Bradford AB, Hoffman KM, Mason SJ, McNutt PM.
    Toxicon; 2018 Jun 01; 147():47-53. PubMed ID: 29054436
    [Abstract] [Full Text] [Related]

  • 2. Use-dependent potentiation of voltage-gated calcium channels rescues neurotransmission in nerve terminals intoxicated by botulinum neurotoxin serotype A.
    Beske PH, Hoffman KM, Machamer JB, Eisen MR, McNutt PM.
    Sci Rep; 2017 Nov 20; 7(1):15862. PubMed ID: 29158500
    [Abstract] [Full Text] [Related]

  • 3. 3,4-diaminopyridine reverses paralysis in botulinum neurotoxin-intoxicated diaphragms through two functionally distinct mechanisms.
    Bradford AB, Machamer JB, Russo TM, McNutt PM.
    Toxicol Appl Pharmacol; 2018 Feb 15; 341():77-86. PubMed ID: 29366638
    [Abstract] [Full Text] [Related]

  • 4. Reversal of BoNT/A-mediated inhibition of muscle paralysis by 3,4-diaminopyridine and roscovitine in mouse phrenic nerve-hemidiaphragm preparations.
    Adler M, Deshpande SS, Apland JP, Murray B, Borrell A.
    Neurochem Int; 2012 Nov 15; 61(6):866-73. PubMed ID: 22841859
    [Abstract] [Full Text] [Related]

  • 5. Botulinum and Tetanus Neurotoxin-Induced Blockade of Synaptic Transmission in Networked Cultures of Human and Rodent Neurons.
    Beske PH, Bradford AB, Grynovicki JO, Glotfelty EJ, Hoffman KM, Hubbard KS, Tuznik KM, McNutt PM.
    Toxicol Sci; 2016 Feb 15; 149(2):503-15. PubMed ID: 26615023
    [Abstract] [Full Text] [Related]

  • 6. Multiple domains of botulinum neurotoxin contribute to its inhibition of transmitter release in Aplysia neurons.
    Poulain B, Wadsworth JD, Shone CC, Mochida S, Lande S, Melling J, Dolly JO, Tauc L.
    J Biol Chem; 1989 Dec 25; 264(36):21928-33. PubMed ID: 2574722
    [Abstract] [Full Text] [Related]

  • 7. Development of neutralizing scFv-Fc against botulinum neurotoxin A light chain from a macaque immune library.
    Miethe S, Rasetti-Escargueil C, Liu Y, Chahboun S, Pelat T, Avril A, Frenzel A, Schirrmann T, Thullier P, Sesardic D, Hust M.
    MAbs; 2014 Dec 25; 6(2):446-59. PubMed ID: 24492304
    [Abstract] [Full Text] [Related]

  • 8. Botulinum Neurotoxins: Qualitative and Quantitative Analysis Using the Mouse Phrenic Nerve Hemidiaphragm Assay (MPN).
    Bigalke H, Rummel A.
    Toxins (Basel); 2015 Nov 25; 7(12):4895-905. PubMed ID: 26610569
    [Abstract] [Full Text] [Related]

  • 9. Interactions between heavy metal chelators and botulinum neurotoxins at the mouse neuromuscular junction.
    Sheridan RE, Deshpande SS.
    Toxicon; 1995 Apr 25; 33(4):539-49. PubMed ID: 7570639
    [Abstract] [Full Text] [Related]

  • 10. Natural Compounds and Their Analogues as Potent Antidotes against the Most Poisonous Bacterial Toxin.
    Patel KB, Cai S, Adler M, Singh BK, Parmar VS, Singh BR.
    Appl Environ Microbiol; 2018 Dec 15; 84(24):. PubMed ID: 30389764
    [Abstract] [Full Text] [Related]

  • 11. Functional evaluation of biological neurotoxins in networked cultures of stem cell-derived central nervous system neurons.
    Hubbard K, Beske P, Lyman M, McNutt P.
    J Vis Exp; 2015 Feb 05; (96):. PubMed ID: 25742030
    [Abstract] [Full Text] [Related]

  • 12. A comparison of biological activity of commercially available purified native botulinum neurotoxin serotypes A1 to F1 in vitro, ex vivo, and in vivo.
    Donald S, Elliott M, Gray B, Hornby F, Lewandowska A, Marlin S, Favre-Guilmard C, Périer C, Cornet S, Kalinichev M, Krupp J, Fonfria E.
    Pharmacol Res Perspect; 2018 Dec 05; 6(6):e00446. PubMed ID: 30519475
    [Abstract] [Full Text] [Related]

  • 13. Embryonic stem cell-derived neurons are a novel, highly sensitive tissue culture platform for botulinum research.
    McNutt P, Celver J, Hamilton T, Mesngon M.
    Biochem Biophys Res Commun; 2011 Feb 04; 405(1):85-90. PubMed ID: 21215258
    [Abstract] [Full Text] [Related]

  • 14. Mastoparan-7 rescues botulinum toxin-A poisoned neurons in a mouse spinal cord cell culture model.
    Zhang P, Ray R, Singh BR, Ray P.
    Toxicon; 2013 Dec 15; 76():37-43. PubMed ID: 24047963
    [Abstract] [Full Text] [Related]

  • 15. Botulinum neurotoxins C, E and F bind gangliosides via a conserved binding site prior to stimulation-dependent uptake with botulinum neurotoxin F utilising the three isoforms of SV2 as second receptor.
    Rummel A, Häfner K, Mahrhold S, Darashchonak N, Holt M, Jahn R, Beermann S, Karnath T, Bigalke H, Binz T.
    J Neurochem; 2009 Sep 15; 110(6):1942-54. PubMed ID: 19650874
    [Abstract] [Full Text] [Related]

  • 16. A study of zinc-dependent metalloendopeptidase inhibitors as pharmacological antagonists in botulinum neurotoxin poisoning.
    Deshpande SS, Sheridan RE, Adler M.
    Toxicon; 1995 Apr 15; 33(4):551-7. PubMed ID: 7570640
    [Abstract] [Full Text] [Related]

  • 17. Symptomatic relief of botulinum neurotoxin/a intoxication with aminopyridines: a new twist on an old molecule.
    Mayorov AV, Willis B, Di Mola A, Adler D, Borgia J, Jackson O, Wang J, Luo Y, Tang L, Knapp RJ, Natarajan C, Goodnough MC, Zilberberg N, Simpson LL, Janda KD.
    ACS Chem Biol; 2010 Dec 17; 5(12):1183-91. PubMed ID: 20936877
    [Abstract] [Full Text] [Related]

  • 18. Neuromuscular recovery from botulism involves multiple forms of compensatory plasticity.
    Machamer JB, Vazquez-Cintron EJ, Stenslik MJ, Pagarigan KT, Bradford AB, Ondeck CA, McNutt PM.
    Front Cell Neurosci; 2023 Dec 17; 17():1226194. PubMed ID: 37650071
    [Abstract] [Full Text] [Related]

  • 19. Botulinum neurotoxin serotype D attacks neurons via two carbohydrate-binding sites in a ganglioside-dependent manner.
    Strotmeier J, Lee K, Völker AK, Mahrhold S, Zong Y, Zeiser J, Zhou J, Pich A, Bigalke H, Binz T, Rummel A, Jin R.
    Biochem J; 2010 Oct 15; 431(2):207-16. PubMed ID: 20704566
    [Abstract] [Full Text] [Related]

  • 20. Transynaptic Action of Botulinum Neurotoxin Type A at Central Cholinergic Boutons.
    Caleo M, Spinelli M, Colosimo F, Matak I, Rossetto O, Lackovic Z, Restani L.
    J Neurosci; 2018 Nov 28; 38(48):10329-10337. PubMed ID: 30315128
    [Abstract] [Full Text] [Related]

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