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PUBMED FOR HANDHELDS

Journal Abstract Search


179 related items for PubMed ID: 29066190

  • 1. Identification of new shikonin derivatives as STAT3 inhibitors.
    Qiu HY, Fu JY, Yang MK, Han HW, Wang PF, Zhang YH, Lin HY, Tang CY, Qi JL, Yang RW, Wang XM, Zhu HL, Yang YH.
    Biochem Pharmacol; 2017 Dec 15; 146():74-86. PubMed ID: 29066190
    [Abstract] [Full Text] [Related]

  • 2. Identification of New Shikonin Derivatives as Antitumor Agents Targeting STAT3 SH2 Domain.
    Qiu HY, Zhu X, Luo YL, Lin HY, Tang CY, Qi JL, Pang YJ, Yang RW, Lu GH, Wang XM, Yang YH.
    Sci Rep; 2017 Jun 06; 7(1):2863. PubMed ID: 28588262
    [Abstract] [Full Text] [Related]

  • 3. Design, synthesis and biological evaluation of benzoylacrylic acid shikonin ester derivatives as irreversible dual inhibitors of tubulin and EGFR.
    Sun WX, Han HW, Yang MK, Wen ZL, Wang YS, Fu JY, Lu YT, Wang MY, Bao JX, Lu GH, Qi JL, Wang XM, Lin HY, Yang YH.
    Bioorg Med Chem; 2019 Dec 01; 27(23):115153. PubMed ID: 31648877
    [Abstract] [Full Text] [Related]

  • 4. Design, synthesis and biological evaluation of novel plumbagin derivatives as potent antitumor agents with STAT3 inhibition.
    Li N, Ou J, Bao N, Chen C, Shi Z, Chen L, Sun J.
    Bioorg Chem; 2020 Nov 01; 104():104208. PubMed ID: 32919131
    [Abstract] [Full Text] [Related]

  • 5. A novel series of napabucasin derivatives as orally active inhibitors of signal transducer and activator of transcription 3 (STAT3).
    Li C, Chen C, An Q, Yang T, Sang Z, Yang Y, Ju Y, Tong A, Luo Y.
    Eur J Med Chem; 2019 Jan 15; 162():543-554. PubMed ID: 30472602
    [Abstract] [Full Text] [Related]

  • 6. RIP1K and RIP3K provoked by shikonin induce cell cycle arrest in the triple negative breast cancer cell line, MDA-MB-468: necroptosis as a desperate programmed suicide pathway.
    Shahsavari Z, Karami-Tehrani F, Salami S, Ghasemzadeh M.
    Tumour Biol; 2016 Apr 15; 37(4):4479-91. PubMed ID: 26496737
    [Abstract] [Full Text] [Related]

  • 7. Synthesis of aryl dihydrothiazol acyl shikonin ester derivatives as anticancer agents through microtubule stabilization.
    Lin HY, Li ZK, Bai LF, Baloch SK, Wang F, Qiu HY, Wang X, Qi JL, Yang RW, Wang XM, Yang YH.
    Biochem Pharmacol; 2015 Jul 15; 96(2):93-106. PubMed ID: 25957661
    [Abstract] [Full Text] [Related]

  • 8. Napabucasin and Related Heterocycle-Fused Naphthoquinones as STAT3 Inhibitors with Antiproliferative Activity against Cancer Cells.
    Löcken H, Clamor C, Müller K.
    J Nat Prod; 2018 Jul 27; 81(7):1636-1644. PubMed ID: 30003778
    [Abstract] [Full Text] [Related]

  • 9. Targeting Cell Necroptosis and Apoptosis Induced by Shikonin via Receptor Interacting Protein Kinases in Estrogen Receptor Positive Breast Cancer Cell Line, MCF-7.
    Shahsavari Z, Karami-Tehrani F, Salami S.
    Anticancer Agents Med Chem; 2018 Jul 27; 18(2):245-254. PubMed ID: 28933271
    [Abstract] [Full Text] [Related]

  • 10. Shikonin N-benzyl matrinic acid ester derivatives as novel telomerase inhibitors with potent activity against lung cancer cell lines.
    Han H, He C, Chen X, Luo Y, Yang M, Wen Z, Hu J, Lin F, Han M, Yin T, Yang R, Lin H, Qi J, Yang Y.
    Bioorg Med Chem Lett; 2022 Feb 01; 57():128503. PubMed ID: 34922028
    [Abstract] [Full Text] [Related]

  • 11. Design, synthesis and biological evaluation of novel potent STAT3 inhibitors based on BBI608 for cancer therapy.
    Feng KR, Wang F, Shi XW, Tan YX, Zhao JY, Zhang JW, Li QH, Lin GQ, Gao D, Tian P.
    Eur J Med Chem; 2020 Sep 01; 201():112428. PubMed ID: 32603980
    [Abstract] [Full Text] [Related]

  • 12. Design, synthesis and biological evaluation of novel naphthoquinothiazole derivatives as potent antitumor agents through inhibiting STAT3.
    Fan D, Liu P, Li Z, He X, Zhang L, Jiang W, Ang W, Yang T.
    Bioorg Chem; 2024 Sep 01; 150():107565. PubMed ID: 38905884
    [Abstract] [Full Text] [Related]

  • 13. 10,11-dehydrocurvularin exerts antitumor effect against human breast cancer by suppressing STAT3 activation.
    Zhao Q, Bi Y, Zhong J, Li X, Guo J, Liu YX, Pan LR, Tan Y, Deng ZS, Yu XJ.
    Acta Pharmacol Sin; 2021 May 01; 42(5):791-800. PubMed ID: 32868906
    [Abstract] [Full Text] [Related]

  • 14. Quercetin induces caspase-dependent extrinsic apoptosis through inhibition of signal transducer and activator of transcription 3 signaling in HER2-overexpressing BT-474 breast cancer cells.
    Seo HS, Ku JM, Choi HS, Choi YK, Woo JK, Kim M, Kim I, Na CH, Hur H, Jang BH, Shin YC, Ko SG.
    Oncol Rep; 2016 Jul 01; 36(1):31-42. PubMed ID: 27175602
    [Abstract] [Full Text] [Related]

  • 15. Cosmomycin C inhibits signal transducer and activator of transcription 3 (STAT3) pathways in MDA-MB-468 breast cancer cell.
    Kim J, Lee YJ, Shin DS, Jeon SH, Son KH, Han DC, Jung SN, Oh TK, Kwon BM.
    Bioorg Med Chem; 2011 Dec 15; 19(24):7582-9. PubMed ID: 22071520
    [Abstract] [Full Text] [Related]

  • 16. Withaferin A inhibits activation of signal transducer and activator of transcription 3 in human breast cancer cells.
    Lee J, Hahm ER, Singh SV.
    Carcinogenesis; 2010 Nov 15; 31(11):1991-8. PubMed ID: 20724373
    [Abstract] [Full Text] [Related]

  • 17. Discovery, synthesis, and evaluation of small-molecule signal transducer and activator of transcription 3 inhibitors.
    Shi ZB, Zhao D, Huang YY, Du Y, Cao XR, Gong ZN, Zhao R, Li JX.
    Chem Pharm Bull (Tokyo); 2012 Nov 15; 60(12):1574-80. PubMed ID: 23207637
    [Abstract] [Full Text] [Related]

  • 18. Activation of ALDH1A1 in MDA-MB-468 breast cancer cells that over-express CYP2J2 protects against paclitaxel-dependent cell death mediated by reactive oxygen species.
    Allison SE, Chen Y, Petrovic N, Zhang J, Bourget K, Mackenzie PI, Murray M.
    Biochem Pharmacol; 2017 Nov 01; 143():79-89. PubMed ID: 28756208
    [Abstract] [Full Text] [Related]

  • 19. Discovery of fluorescent coumarin-benzo[b]thiophene 1, 1-dioxide conjugates as mitochondria-targeting antitumor STAT3 inhibitors.
    Cai G, Yu W, Song D, Zhang W, Guo J, Zhu J, Ren Y, Kong L.
    Eur J Med Chem; 2019 Jul 15; 174():236-251. PubMed ID: 31048139
    [Abstract] [Full Text] [Related]

  • 20. Synthesis and biological activity of novel shikonin analogues.
    Wang W, Dai M, Zhu C, Zhang J, Lin L, Ding J, Duan W.
    Bioorg Med Chem Lett; 2009 Feb 01; 19(3):735-7. PubMed ID: 19111464
    [Abstract] [Full Text] [Related]


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