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172 related items for PubMed ID: 2907421

  • 1. Inhibitors of sterol synthesis. Studies of the metabolism of 5 alpha-cholest-8(14)-en-3 beta-ol-15-one in Chinese hamster ovary cells and its effects on activities of early enzymes in cholesterol biosynthesis.
    Pajewski TN, Pinkerton FD, Miller LR, Schroepfer GJ.
    Chem Phys Lipids; 1988 Oct; 48(3-4):153-68. PubMed ID: 2907421
    [Abstract] [Full Text] [Related]

  • 2. Inhibitors of sterol synthesis. Effects of dietary 5 alpha-cholest-8(14)-en-3 beta-ol-15-one on early enzymes in hepatic cholesterol biosynthesis.
    Miller LR, Raulston DL, Schroepfer GJ.
    Chem Phys Lipids; 1988 Jul; 47(3):177-86. PubMed ID: 2901919
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  • 3. Inhibitors of cholesterol biosynthesis. Further studies of the metabolism of 5 alpha-cholest-8(14)-en-3 beta-ol-15-one in rat liver preparations.
    Monger DJ, Schroepfer GJ.
    Chem Phys Lipids; 1988 May; 47(1):21-46. PubMed ID: 3396133
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  • 4. Sterol synthesis. Synthesis of 3 beta-hydroxy-25,26,26,26,27,27,27-heptafluorocholest-5-en-7-one and its effects on HMG-CoA reductase activity in Chinese hamster ovary cells, on ACAT activity in rat jejunal microsomes, and serum cholesterol levels in rats.
    Carroll JN, Pinkerton FD, Su X, Gerst N, Wilson WK, Schroepfer GJ.
    Chem Phys Lipids; 1998 Aug; 94(2):209-25. PubMed ID: 9779586
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  • 5. Analysis of the coordinate expression of 3-hydroxy-3-methylglutaryl coenzyme A synthase and reductase activities in Chinese hamster ovary fibroblasts.
    Schnitzer-Polokoff R, Torget R, Logel J, Sinensky M.
    Arch Biochem Biophys; 1983 Nov; 227(1):71-80. PubMed ID: 6139093
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  • 8. Regulation of cholesterol synthesis in rat adrenal gland through coordinate control of 3-hydroxy-3-methylglutaryl coenzyme A synthase and reductase activities.
    Balasubramaniam S, Goldstein JL, Brown MS.
    Proc Natl Acad Sci U S A; 1977 Apr; 74(4):1421-5. PubMed ID: 16260
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  • 9. Inhibitors of sterol synthesis. The effects of dietary 5 alpha-cholest-8(14)-en-3 beta-ol-15-one on the fate of [4-14C]cholesterol and [2,4-3H]5 alpha-cholest-8(14)-en-3 beta-ol-15-one after intragastric administration to rats.
    Brabson JS, Schroepfer GJ.
    Chem Phys Lipids; 1988 May; 47(1):1-20. PubMed ID: 3396132
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  • 11. Inhibitors of sterol synthesis. Metabolism of [2,4-3H]5 alpha-cholest-8(14)-en-3 beta-ol-15-one after oral administration to a nonhuman primate.
    Pajewski TN, Brabson JS, Kisic A, Wang KS, Hylarides MD, Jackson EM, Schroepfer GJ.
    Chem Phys Lipids; 1989 Mar; 49(4):243-63. PubMed ID: 2720860
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  • 12. Regulation of hepatic cholesterol biosynthesis by fatty acids: effect of feeding olive oil on cytoplasmic acetoacetyl-coenzyme A thiolase, beta-hydroxy-beta-methylglutaryl-CoA synthase, and acetoacetyl-coenzyme A ligase.
    Salam WH, Cagen LM, Heimberg M.
    Biochem Biophys Res Commun; 1988 May 31; 153(1):422-7. PubMed ID: 2897853
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  • 13. Regulation of early cholesterol biosynthesis in rat liver: effects of sterols, bile acids, lovastatin, and BM 15.766 on 3-hydroxy-3-methylglutaryl coenzyme A synthase and acetoacetyl coenzyme A thiolase activities.
    Honda A, Salen G, Nguyen LB, Xu G, Tint GS, Batta AK, Shefer S.
    Hepatology; 1998 Jan 31; 27(1):154-9. PubMed ID: 9425931
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  • 14. Inhibitors of sterol synthesis. Chemical synthesis of 7 alpha-ethyl and 16 alpha-ethyl derivatives of delta 8(14)-15-oxygenated sterols and their effects on 3-hydroxy-3-methylglutaryl coenzyme A reductase in CHO-K1 cells.
    Kim HS, Wilson WK, Kirkpatrick ND, Pinkerton FD, Swaminathan S, Hylarides MD, Schroepfer GJ.
    Chem Phys Lipids; 1992 Jul 31; 62(1):55-67. PubMed ID: 1423803
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  • 15. Inhibitors of sterol synthesis: effects of a 7 alpha-alkyl analog of 3 beta-hydroxy-5 alpha-cholest-8(14)-en-15-one on 3-hydroxy-3-methylglutaryl coenzyme A reductase activity in cultured mammalian cells and on serum cholesterol levels and other parameters in rats.
    Siddiqui AU, Gerst N, Kim LJ, Pinkerton FD, Kisic A, Wilson WK, Schroepfer GJ.
    Chem Phys Lipids; 1994 Apr 19; 70(2):163-78. PubMed ID: 8033288
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  • 16. Modulation of 3-hydroxy-3-methylglutaryl-CoA reductase by 15 alpha-fluorolanost-7-en-3 beta-ol. A mechanism-based inhibitor of cholesterol biosynthesis.
    Trzaskos JM, Magolda RL, Favata MF, Fischer RT, Johnson PR, Chen HW, Ko SS, Leonard DA, Gaylor JL.
    J Biol Chem; 1993 Oct 25; 268(30):22591-9. PubMed ID: 7693673
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  • 17. Inhibitors of sterol synthesis. A major role of chylomicrons in the metabolism of 5 alpha-cholest-8(14)-en-3 beta-ol-15-one in the rat.
    Schroepfer GJ, Christophe A, Chu AJ, Izumi A, Kisic A, Sherrill BC.
    Chem Phys Lipids; 1988 Sep 25; 48(1-2):29-58. PubMed ID: 3208415
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  • 18. Inhibitors of sterol synthesis. Chemical synthesis and properties of 3 beta-hydroxy-25,26,26,26,27,27,27-heptafluoro-5 alpha-cholest-8(14)-en-15-one and 25,26,26,26,27,27,27-heptafluorocholesterol and their effects on 3-hydroxy-3-methylglutaryl coenzyme A reductase activity in cultured mammalian cells.
    Swaminathan S, Wilson WK, Pinkerton FD, Gerst N, Ramser M, Schroepfer GJ.
    J Lipid Res; 1993 Oct 25; 34(10):1805-23. PubMed ID: 8245728
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  • 19. The effect of mevinolin on cytosolic acetoacetyl coenzyme a thiolase activity in Chinese hamster ovary fibroblasts.
    Schnitzer-Polokoff R.
    Biochem Biophys Res Commun; 1986 Jul 31; 138(2):953-9. PubMed ID: 2874807
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  • 20. Inhibitors of sterol synthesis. A highly efficient and specific side-chain oxidation of 3 beta-acetoxy-5 alpha-cholest-8(14)-en-15-one for construction of metabolites and analogs of the 15-ketosterol.
    Herz JE, Swaminathan S, Pinkerton FD, Wilson WK, Schroepfer GJ.
    J Lipid Res; 1992 Apr 31; 33(4):579-98. PubMed ID: 1527481
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