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Journal Abstract Search

409 related items for PubMed ID: 29096096

  • 1. Discovery of triazole-based uracil derivatives bearing amide moieties as novel dipeptidyl peptidase-IV inhibitors.
    Deng X, Han L, Zhou J, Zhang H, Li Q.
    Bioorg Chem; 2017 Dec; 75():357-367. PubMed ID: 29096096
    [Abstract] [Full Text] [Related]

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  • 3. Design, synthesis and anti-diabetic activity of triazolotriazine derivatives as dipeptidyl peptidase-4 (DPP-4) inhibitors.
    Patel BD, Bhadada SV, Ghate MD.
    Bioorg Chem; 2017 Jun; 72():345-358. PubMed ID: 28302310
    [Abstract] [Full Text] [Related]

  • 4. Synthesis, evaluation and molecular docking of thiazolopyrimidine derivatives as dipeptidyl peptidase IV inhibitors.
    Sharma M, Gupta M, Singh D, Kumar M, Kaur P.
    Chem Biol Drug Des; 2012 Dec; 80(6):918-28. PubMed ID: 22943413
    [Abstract] [Full Text] [Related]

  • 5. Identification of novel uracil derivatives incorporating benzoic acid moieties as highly potent Dipeptidyl Peptidase-IV inhibitors.
    Huang J, Deng X, Zhou S, Wang N, Qin Y, Meng L, Li G, Xiong Y, Fan Y, Guo L, Lan D, Xing J, Jiang W, Li Q.
    Bioorg Med Chem; 2019 Feb 15; 27(4):644-654. PubMed ID: 30642693
    [Abstract] [Full Text] [Related]

  • 6. Surrogating and redirection of pyrazolo[1,5-a]pyrimidin-7(4H)-one core, a novel class of potent and selective DPP-4 inhibitors.
    Deng X, Shen J, Zhu H, Xiao J, Sun R, Xie F, Lam C, Wang J, Qiao Y, Tavallaie MS, Hu Y, Du Y, Li J, Fu L, Jiang F.
    Bioorg Med Chem; 2018 Feb 15; 26(4):903-912. PubMed ID: 29373269
    [Abstract] [Full Text] [Related]

  • 7. Rapid generation of novel benzoic acid-based xanthine derivatives as highly potent, selective and long acting DPP-4 inhibitors: Scaffold-hopping and prodrug study.
    Li Q, Meng L, Zhou S, Deng X, Wang N, Ji Y, Peng Y, Xing J, Yao G.
    Eur J Med Chem; 2019 Oct 15; 180():509-523. PubMed ID: 31336309
    [Abstract] [Full Text] [Related]

  • 8. Design, Synthesis and Biological Evaluation of Imidazo[1,2-a]pyridine Derivatives as Novel DPP-4 Inhibitors.
    Li Q, Zhou M, Han L, Cao Q, Wang X, Zhao L, Zhou J, Zhang H.
    Chem Biol Drug Des; 2015 Oct 15; 86(4):849-56. PubMed ID: 25787859
    [Abstract] [Full Text] [Related]

  • 9. Identification of dipeptidyl peptidase IV inhibitors: virtual screening, synthesis and biological evaluation.
    Xing J, Li Q, Zhang S, Liu H, Zhao L, Cheng H, Zhang Y, Zhou J, Zhang H.
    Chem Biol Drug Des; 2014 Sep 15; 84(3):364-77. PubMed ID: 24674599
    [Abstract] [Full Text] [Related]

  • 10. Synthesis and biological evaluation of novel benzyl-substituted (S)-phenylalanine derivatives as potent dipeptidyl peptidase 4 inhibitors.
    Liu Y, Si M, Tang L, Shangguan S, Wu H, Li J, Wu P, Ma X, Liu T, Hu Y.
    Bioorg Med Chem; 2013 Sep 15; 21(18):5679-87. PubMed ID: 23938053
    [Abstract] [Full Text] [Related]

  • 11. Optimization of the benzamide fragment targeting the S2' site leads to potent dipeptidyl peptidase-IV inhibitors.
    Deng X, Wang N, Meng L, Zhou S, Huang J, Xing J, He L, Jiang W, Li Q.
    Bioorg Chem; 2020 Jan 15; 94():103366. PubMed ID: 31640932
    [Abstract] [Full Text] [Related]

  • 12. Synthesis, Biological Evaluation, and Molecular Docking of (R)-2-((8-(3-aminopiperidin-1-yl)-3-methyl-7-(3-methylbut-2-en-1-yl)-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-1-yl)methyl)benzonitrile as Dipeptidyl Peptidase IV Inhibitors.
    Ran Y, Pei H, Shao M, Chen L.
    Chem Biol Drug Des; 2016 Feb 15; 87(2):290-5. PubMed ID: 26426933
    [Abstract] [Full Text] [Related]

  • 13. Discovery of novel xanthine compounds targeting DPP-IV and GPR119 as anti-diabetic agents.
    Li G, Huan Y, Yuan B, Wang J, Jiang Q, Lin Z, Shen Z, Huang H.
    Eur J Med Chem; 2016 Nov 29; 124():103-116. PubMed ID: 27560285
    [Abstract] [Full Text] [Related]

  • 14. Synthesis and biological evaluation of pyrrolidine-2-carbonitrile and 4-fluoropyrrolidine-2-carbonitrile derivatives as dipeptidyl peptidase-4 inhibitors for the treatment of type 2 diabetes.
    Wang J, Feng Y, Ji X, Deng G, Leng Y, Liu H.
    Bioorg Med Chem; 2013 Dec 01; 21(23):7418-29. PubMed ID: 24153396
    [Abstract] [Full Text] [Related]

  • 15. Discovery of highly potent DPP-4 inhibitors by hybrid compound design based on linagliptin and alogliptin.
    Lai ZW, Li C, Liu J, Kong L, Wen X, Sun H.
    Eur J Med Chem; 2014 Aug 18; 83():547-60. PubMed ID: 24996141
    [Abstract] [Full Text] [Related]

  • 16. Finding a Potential Dipeptidyl Peptidase-4 (DPP-4) Inhibitor for Type-2 Diabetes Treatment Based on Molecular Docking, Pharmacophore Generation, and Molecular Dynamics Simulation.
    Meduru H, Wang YT, Tsai JJ, Chen YC.
    Int J Mol Sci; 2016 Jun 13; 17(6):. PubMed ID: 27304951
    [Abstract] [Full Text] [Related]

  • 17. Recent progress of the development of dipeptidyl peptidase-4 inhibitors for the treatment of type 2 diabetes mellitus.
    Li N, Wang LJ, Jiang B, Li XQ, Guo CL, Guo SJ, Shi DY.
    Eur J Med Chem; 2018 May 10; 151():145-157. PubMed ID: 29609120
    [Abstract] [Full Text] [Related]

  • 18. Synthesis, nitric oxide release, and dipeptidyl peptidase-4 inhibition of sitagliptin derivatives as new multifunctional antidiabetic agents.
    Xie Y, Shao L, Wang Q, Bai Y, Chen Z, Li N, Xu Y, Li Y, Yang G, Bian X.
    Bioorg Med Chem Lett; 2018 Dec 15; 28(23-24):3731-3735. PubMed ID: 30343953
    [Abstract] [Full Text] [Related]

  • 19. Identification and structure-activity relationship exploration of uracil-based benzoic acid and ester derivatives as novel dipeptidyl Peptidase-4 inhibitors for the treatment of type 2 diabetes mellitus.
    Li Q, Deng X, Jiang N, Meng L, Xing J, Jiang W, Xu Y.
    Eur J Med Chem; 2021 Dec 05; 225():113765. PubMed ID: 34399391
    [Abstract] [Full Text] [Related]

  • 20. Synthesis, evaluation and molecular docking of prolyl-fluoropyrrolidine derivatives as dipeptidyl peptidase IV inhibitors.
    Sharma M, Gupta M, Singh D, Kumar M, Kaur P.
    Chem Biol Drug Des; 2013 Aug 05; 82(2):156-66. PubMed ID: 23581745
    [Abstract] [Full Text] [Related]

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