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820 related items for PubMed ID: 29126913

  • 1. IWR-1, a tankyrase inhibitor, attenuates Wnt/β-catenin signaling in cancer stem-like cells and inhibits in vivo the growth of a subcutaneous human osteosarcoma xenograft.
    Martins-Neves SR, Paiva-Oliveira DI, Fontes-Ribeiro C, Bovée JVMG, Cleton-Jansen AM, Gomes CMF.
    Cancer Lett; 2018 Feb 01; 414():1-15. PubMed ID: 29126913
    [Abstract] [Full Text] [Related]

  • 2. WM130 preferentially inhibits hepatic cancer stem-like cells by suppressing AKT/GSK3β/β-catenin signaling pathway.
    Ni CX, Qi Y, Zhang J, Liu Y, Xu WH, Xu J, Hu HG, Wu QY, Wang Y, Zhang JP.
    Oncotarget; 2016 Nov 29; 7(48):79544-79556. PubMed ID: 27783993
    [Abstract] [Full Text] [Related]

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  • 4. Targeted inhibition of T-cell factor activity promotes syndecan-2 expression and sensitization to doxorubicin in osteosarcoma cells and bone tumors in mice.
    Dieudonné FX, Marion A, Marie PJ, Modrowski D.
    J Bone Miner Res; 2012 Oct 29; 27(10):2118-29. PubMed ID: 22550000
    [Abstract] [Full Text] [Related]

  • 5. Tankyrase inhibitors attenuate WNT/β-catenin signaling and inhibit growth of hepatocellular carcinoma cells.
    Ma L, Wang X, Jia T, Wei W, Chua MS, So S.
    Oncotarget; 2015 Sep 22; 6(28):25390-401. PubMed ID: 26246473
    [Abstract] [Full Text] [Related]

  • 6. IWR-1 inhibits epithelial-mesenchymal transition of colorectal cancer cells through suppressing Wnt/β-catenin signaling as well as survivin expression.
    Lee SC, Kim OH, Lee SK, Kim SJ.
    Oncotarget; 2015 Sep 29; 6(29):27146-59. PubMed ID: 26450645
    [Abstract] [Full Text] [Related]

  • 7. mTOR signaling mediates resistance to tankyrase inhibitors in Wnt-driven colorectal cancer.
    Mashima T, Taneda Y, Jang MK, Mizutani A, Muramatsu Y, Yoshida H, Sato A, Tanaka N, Sugimoto Y, Seimiya H.
    Oncotarget; 2017 Jul 18; 8(29):47902-47915. PubMed ID: 28615517
    [Abstract] [Full Text] [Related]

  • 8. MicroRNA-1 down-regulates proliferation and migration of breast cancer stem cells by inhibiting the Wnt/β-catenin pathway.
    Liu T, Hu K, Zhao Z, Chen G, Ou X, Zhang H, Zhang X, Wei X, Wang D, Cui M, Liu C.
    Oncotarget; 2015 Dec 08; 6(39):41638-49. PubMed ID: 26497855
    [Abstract] [Full Text] [Related]

  • 9. Tankyrase Inhibition Blocks Wnt/β-Catenin Pathway and Reverts Resistance to PI3K and AKT Inhibitors in the Treatment of Colorectal Cancer.
    Arqués O, Chicote I, Puig I, Tenbaum SP, Argilés G, Dienstmann R, Fernández N, Caratù G, Matito J, Silberschmidt D, Rodon J, Landolfi S, Prat A, Espín E, Charco R, Nuciforo P, Vivancos A, Shao W, Tabernero J, Palmer HG.
    Clin Cancer Res; 2016 Feb 01; 22(3):644-56. PubMed ID: 26224873
    [Abstract] [Full Text] [Related]

  • 10. Evidence for tankyrases as antineoplastic targets in lung cancer.
    Busch AM, Johnson KC, Stan RV, Sanglikar A, Ahmed Y, Dmitrovsky E, Freemantle SJ.
    BMC Cancer; 2013 Apr 28; 13():211. PubMed ID: 23621985
    [Abstract] [Full Text] [Related]

  • 11. Osteosarcoma Stem Cells Have Active Wnt/β-catenin and Overexpress SOX2 and KLF4.
    Martins-Neves SR, Corver WE, Paiva-Oliveira DI, van den Akker BE, Briaire-de-Bruijn IH, Bovée JV, Gomes CM, Cleton-Jansen AM.
    J Cell Physiol; 2016 Apr 28; 231(4):876-86. PubMed ID: 26332365
    [Abstract] [Full Text] [Related]

  • 12. Aberrant Wnt/β-catenin signaling and elevated expression of stem cell proteins are associated with osteosarcoma side population cells of high tumorigenicity.
    Yi XJ, Zhao YH, Qiao LX, Jin CL, Tian J, Li QS.
    Mol Med Rep; 2015 Oct 28; 12(4):5042-8. PubMed ID: 26134785
    [Abstract] [Full Text] [Related]

  • 13. Gamma-Secretase Inhibitor IX (GSI) Impairs Concomitant Activation of Notch and Wnt-Beta-Catenin Pathways in CD44+ Gastric Cancer Stem Cells.
    Barat S, Chen X, Cuong Bui K, Bozko P, Götze J, Christgen M, Krech T, Malek NP, Plentz RR.
    Stem Cells Transl Med; 2017 Mar 28; 6(3):819-829. PubMed ID: 28186678
    [Abstract] [Full Text] [Related]

  • 14. The Wnt/β-catenin pathway regulates self-renewal of cancer stem-like cells in human gastric cancer.
    Cai C, Zhu X.
    Mol Med Rep; 2012 May 28; 5(5):1191-6. PubMed ID: 22367735
    [Abstract] [Full Text] [Related]

  • 15. Tankyrase Inhibitors Target Colorectal Cancer Stem Cells via AXIN-Dependent Downregulation of c-KIT Tyrosine Kinase.
    Jang MK, Mashima T, Seimiya H.
    Mol Cancer Ther; 2020 Mar 28; 19(3):765-776. PubMed ID: 31907221
    [Abstract] [Full Text] [Related]

  • 16. APC Mutations as a Potential Biomarker for Sensitivity to Tankyrase Inhibitors in Colorectal Cancer.
    Tanaka N, Mashima T, Mizutani A, Sato A, Aoyama A, Gong B, Yoshida H, Muramatsu Y, Nakata K, Matsuura M, Katayama R, Nagayama S, Fujita N, Sugimoto Y, Seimiya H.
    Mol Cancer Ther; 2017 Apr 28; 16(4):752-762. PubMed ID: 28179481
    [Abstract] [Full Text] [Related]

  • 17. Ginsenoside-Rb1 targets chemotherapy-resistant ovarian cancer stem cells via simultaneous inhibition of Wnt/β-catenin signaling and epithelial-to-mesenchymal transition.
    Deng S, Wong CKC, Lai HC, Wong AST.
    Oncotarget; 2017 Apr 18; 8(16):25897-25914. PubMed ID: 27825116
    [Abstract] [Full Text] [Related]

  • 18. A novel tankyrase small-molecule inhibitor suppresses APC mutation-driven colorectal tumor growth.
    Lau T, Chan E, Callow M, Waaler J, Boggs J, Blake RA, Magnuson S, Sambrone A, Schutten M, Firestein R, Machon O, Korinek V, Choo E, Diaz D, Merchant M, Polakis P, Holsworth DD, Krauss S, Costa M.
    Cancer Res; 2013 May 15; 73(10):3132-44. PubMed ID: 23539443
    [Abstract] [Full Text] [Related]

  • 19. Downregulation of Cancer Stemness by Novel Diterpenoid Ovatodiolide Inhibits Hepatic Cancer Stem Cell-Like Traits by Repressing Wnt/[Formula: see text]-Catenin Signaling.
    Liu M, Bamodu OA, Kuo KT, Lee WH, Lin YK, Wu ATH, M H, Tzeng YM, Yeh CT, Tsai JT.
    Am J Chin Med; 2018 May 15; 46(4):891-910. PubMed ID: 29792038
    [Abstract] [Full Text] [Related]

  • 20. The Anti-Tumor Activity of Succinyl Macrolactin A Is Mediated through the β-Catenin Destruction Complex via the Suppression of Tankyrase and PI3K/Akt.
    Regmi SC, Park SY, Kim SJ, Banskota S, Shah S, Kim DH, Kim JA.
    PLoS One; 2015 May 15; 10(11):e0141753. PubMed ID: 26544726
    [Abstract] [Full Text] [Related]

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