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162 related items for PubMed ID: 29158482

  • 1. Structural basis for the unique ganglioside and cell membrane recognition mechanism of botulinum neurotoxin DC.
    Zhang S, Berntsson RP, Tepp WH, Tao L, Johnson EA, Stenmark P, Dong M.
    Nat Commun; 2017 Nov 21; 8(1):1637. PubMed ID: 29158482
    [Abstract] [Full Text] [Related]

  • 2. Botulinum neurotoxin serotype C associates with dual ganglioside receptors to facilitate cell entry.
    Karalewitz AP, Fu Z, Baldwin MR, Kim JJ, Barbieri JT.
    J Biol Chem; 2012 Nov 23; 287(48):40806-16. PubMed ID: 23027864
    [Abstract] [Full Text] [Related]

  • 3. Botulinum neurotoxin serotype D attacks neurons via two carbohydrate-binding sites in a ganglioside-dependent manner.
    Strotmeier J, Lee K, Völker AK, Mahrhold S, Zong Y, Zeiser J, Zhou J, Pich A, Bigalke H, Binz T, Rummel A, Jin R.
    Biochem J; 2010 Oct 15; 431(2):207-16. PubMed ID: 20704566
    [Abstract] [Full Text] [Related]

  • 4. The biological activity of botulinum neurotoxin type C is dependent upon novel types of ganglioside binding sites.
    Strotmeier J, Gu S, Jutzi S, Mahrhold S, Zhou J, Pich A, Eichner T, Bigalke H, Rummel A, Jin R, Binz T.
    Mol Microbiol; 2011 Jul 15; 81(1):143-56. PubMed ID: 21542861
    [Abstract] [Full Text] [Related]

  • 5. Unique ganglioside binding by botulinum neurotoxins C and D-SA.
    Kroken AR, Karalewitz AP, Fu Z, Baldwin MR, Kim JJ, Barbieri JT.
    FEBS J; 2011 Dec 15; 278(23):4486-96. PubMed ID: 21554541
    [Abstract] [Full Text] [Related]

  • 6. Unique biological activity of botulinum D/C mosaic neurotoxin in murine species.
    Nakamura K, Kohda T, Shibata Y, Tsukamoto K, Arimitsu H, Hayashi M, Mukamoto M, Sasakawa N, Kozaki S.
    Infect Immun; 2012 Aug 15; 80(8):2886-93. PubMed ID: 22665374
    [Abstract] [Full Text] [Related]

  • 7. Glycosylated SV2 and gangliosides as dual receptors for botulinum neurotoxin serotype F.
    Fu Z, Chen C, Barbieri JT, Kim JJ, Baldwin MR.
    Biochemistry; 2009 Jun 23; 48(24):5631-41. PubMed ID: 19476346
    [Abstract] [Full Text] [Related]

  • 8. Mechanism of Ganglioside Receptor Recognition by Botulinum Neurotoxin Serotype E.
    Masuyer G, Davies JR, Stenmark P.
    Int J Mol Sci; 2021 Aug 02; 22(15):. PubMed ID: 34361086
    [Abstract] [Full Text] [Related]

  • 9. Unique ganglioside recognition strategies for clostridial neurotoxins.
    Benson MA, Fu Z, Kim JJ, Baldwin MR.
    J Biol Chem; 2011 Sep 30; 286(39):34015-22. PubMed ID: 21849494
    [Abstract] [Full Text] [Related]

  • 10. Structural basis of cell surface receptor recognition by botulinum neurotoxin B.
    Chai Q, Arndt JW, Dong M, Tepp WH, Johnson EA, Chapman ER, Stevens RC.
    Nature; 2006 Dec 21; 444(7122):1096-100. PubMed ID: 17167418
    [Abstract] [Full Text] [Related]

  • 11. Receptor binding enables botulinum neurotoxin B to sense low pH for translocation channel assembly.
    Sun S, Suresh S, Liu H, Tepp WH, Johnson EA, Edwardson JM, Chapman ER.
    Cell Host Microbe; 2011 Sep 15; 10(3):237-47. PubMed ID: 21925111
    [Abstract] [Full Text] [Related]

  • 12. Identification of a unique ganglioside binding loop within botulinum neurotoxins C and D-SA .
    Karalewitz AP, Kroken AR, Fu Z, Baldwin MR, Kim JJ, Barbieri JT.
    Biochemistry; 2010 Sep 21; 49(37):8117-26. PubMed ID: 20731382
    [Abstract] [Full Text] [Related]

  • 13. Characterization of a membrane binding loop leads to engineering botulinum neurotoxin B with improved therapeutic efficacy.
    Yin L, Masuyer G, Zhang S, Zhang J, Miyashita SI, Burgin D, Lovelock L, Coker SF, Fu TM, Stenmark P, Dong M.
    PLoS Biol; 2020 Mar 21; 18(3):e3000618. PubMed ID: 32182233
    [Abstract] [Full Text] [Related]

  • 14. Crystal structure of the botulinum neurotoxin type G binding domain: insight into cell surface binding.
    Stenmark P, Dong M, Dupuy J, Chapman ER, Stevens RC.
    J Mol Biol; 2010 Apr 16; 397(5):1287-97. PubMed ID: 20219474
    [Abstract] [Full Text] [Related]

  • 15. Identification of the protein receptor binding site of botulinum neurotoxins B and G proves the double-receptor concept.
    Rummel A, Eichner T, Weil T, Karnath T, Gutcaits A, Mahrhold S, Sandhoff K, Proia RL, Acharya KR, Bigalke H, Binz T.
    Proc Natl Acad Sci U S A; 2007 Jan 02; 104(1):359-64. PubMed ID: 17185412
    [Abstract] [Full Text] [Related]

  • 16. Botulinum neurotoxin D uses synaptic vesicle protein SV2 and gangliosides as receptors.
    Peng L, Tepp WH, Johnson EA, Dong M.
    PLoS Pathog; 2011 Mar 02; 7(3):e1002008. PubMed ID: 21483489
    [Abstract] [Full Text] [Related]

  • 17. Novel ganglioside-mediated entry of botulinum neurotoxin serotype D into neurons.
    Kroken AR, Karalewitz AP, Fu Z, Kim JJ, Barbieri JT.
    J Biol Chem; 2011 Jul 29; 286(30):26828-37. PubMed ID: 21632541
    [Abstract] [Full Text] [Related]

  • 18. Exchange of the H(CC) domain mediating double receptor recognition improves the pharmacodynamic properties of botulinum neurotoxin.
    Rummel A, Mahrhold S, Bigalke H, Binz T.
    FEBS J; 2011 Dec 29; 278(23):4506-15. PubMed ID: 21624052
    [Abstract] [Full Text] [Related]

  • 19. Structural insights into the functional role of the Hcn sub-domain of the receptor-binding domain of the botulinum neurotoxin mosaic serotype C/D.
    Zhang Y, Gardberg AS, Edwards TE, Sankaran B, Robinson H, Varnum SM, Buchko GW.
    Biochimie; 2013 Jul 29; 95(7):1379-85. PubMed ID: 23523511
    [Abstract] [Full Text] [Related]

  • 20. Crystal structure of the receptor binding domain of the botulinum C-D mosaic neurotoxin reveals potential roles of lysines 1118 and 1136 in membrane interactions.
    Zhang Y, Buchko GW, Qin L, Robinson H, Varnum SM.
    Biochem Biophys Res Commun; 2011 Jan 07; 404(1):407-12. PubMed ID: 21130733
    [Abstract] [Full Text] [Related]


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