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76 related items for PubMed ID: 29179029

  • 1. 3EZ, 20Ac-ingenol induces cell-specific apoptosis in cyclin D1 over-expression through the activation of ATR and downregulation of p-Akt.
    Miyata S, Wang LY, Kitanaka S.
    Leuk Res; 2018 Jan; 64():46-51. PubMed ID: 29179029
    [Abstract] [Full Text] [Related]

  • 2. 3EZ, 20Ac-ingenol-induced Apoptosis in Chemoresistant Cancers With Cyclin D1 Accumulation.
    Miyata S, Nakamura T, Kitanaka S.
    Anticancer Res; 2020 Nov; 40(11):6237-6246. PubMed ID: 33109561
    [Abstract] [Full Text] [Related]

  • 3. Mechanism of the inhibition of leukemia cell growth and induction of apoptosis through the activation of ATR and PTEN by the topoisomerase inhibitor 3EZ, 20Ac-ingenol.
    Miyata S, Fukuda Y, Tojima H, Matsuzaki K, Kitanaka S, Sawada H.
    Leuk Res; 2015 Sep; 39(9):927-32. PubMed ID: 26194899
    [Abstract] [Full Text] [Related]

  • 4. Reduction of HIF-1α/PD-L1 by Catalytic Topoisomerase Inhibitor Induces Cell Death Through Caspase Activation in Cancer Cells Under Hypoxia.
    Miyata S, Ishii T, Kitanaka S.
    Anticancer Res; 2024 Jan; 44(1):49-59. PubMed ID: 38159998
    [Abstract] [Full Text] [Related]

  • 5. 3EZ,20Ac-ingenol, a catalytic inhibitor of topoisomerases, downregulates p-Akt and induces DSBs and apoptosis of DT40 cells.
    Fukuda Y, Kanbe M, Watanabe M, Dan K, Matsuzaki K, Kitanaka S, Miyata S.
    Arch Pharm Res; 2013 Aug; 36(8):1029-38. PubMed ID: 23595550
    [Abstract] [Full Text] [Related]

  • 6. 3-O-(2'E,4'Z-decadienoyl)-20-O-acetylingenol induces apoptosis in intestinal epithelial cells of rats via mitochondrial pathway.
    Gao J, Gao L, Zhang L, Yao W, Cao Y, Bao B, Ding A.
    J Ethnopharmacol; 2015 Nov 04; 174():331-8. PubMed ID: 26318745
    [Abstract] [Full Text] [Related]

  • 7. Molecular targeting of Akt by thymoquinone promotes G(1) arrest through translation inhibition of cyclin D1 and induces apoptosis in breast cancer cells.
    Rajput S, Kumar BN, Dey KK, Pal I, Parekh A, Mandal M.
    Life Sci; 2013 Nov 13; 93(21):783-90. PubMed ID: 24044882
    [Abstract] [Full Text] [Related]

  • 8. HBx protein modulates PI3K/Akt pathway to overcome genotoxic stress-induced destabilization of cyclin D1 and arrest of cell cycle.
    Mukherji A, Janbandhu VC, Kumar V.
    Indian J Biochem Biophys; 2009 Feb 13; 46(1):37-44. PubMed ID: 19374252
    [Abstract] [Full Text] [Related]

  • 9. ATM-mediated PTEN phosphorylation promotes PTEN nuclear translocation and autophagy in response to DNA-damaging agents in cancer cells.
    Chen JH, Zhang P, Chen WD, Li DD, Wu XQ, Deng R, Jiao L, Li X, Ji J, Feng GK, Zeng YX, Jiang JW, Zhu XF.
    Autophagy; 2015 Feb 13; 11(2):239-52. PubMed ID: 25701194
    [Abstract] [Full Text] [Related]

  • 10. Ovatodiolide isolated from Anisomeles indica induces cell cycle G2/M arrest and apoptosis via a ROS-dependent ATM/ATR signaling pathways.
    Yu CY, Jerry Teng CL, Hung PS, Cheng CC, Hsu SL, Hwang GY, Tzeng YM.
    Eur J Pharmacol; 2018 Jan 15; 819():16-29. PubMed ID: 28986085
    [Abstract] [Full Text] [Related]

  • 11. Acquired radioresistance of human tumor cells by DNA-PK/AKT/GSK3beta-mediated cyclin D1 overexpression.
    Shimura T, Kakuda S, Ochiai Y, Nakagawa H, Kuwahara Y, Takai Y, Kobayashi J, Komatsu K, Fukumoto M.
    Oncogene; 2010 Aug 26; 29(34):4826-37. PubMed ID: 20562919
    [Abstract] [Full Text] [Related]

  • 12. Luteolin induces G1 arrest in human nasopharyngeal carcinoma cells via the Akt-GSK-3β-Cyclin D1 pathway.
    Ong CS, Zhou J, Ong CN, Shen HM.
    Cancer Lett; 2010 Dec 08; 298(2):167-75. PubMed ID: 20655656
    [Abstract] [Full Text] [Related]

  • 13. Curcumol induces cell cycle arrest in colon cancer cells via reactive oxygen species and Akt/ GSK3β/cyclin D1 pathway.
    Wang J, Li XM, Bai Z, Chi BX, Wei Y, Chen X.
    J Ethnopharmacol; 2018 Jan 10; 210():1-9. PubMed ID: 28684297
    [Abstract] [Full Text] [Related]

  • 14. Activation of the p38 MAPK/Akt/ERK1/2 signal pathways is required for the protein stabilization of CDC6 and cyclin D1 in low-dose arsenite-induced cell proliferation.
    Liu Y, Hock JM, Sullivan C, Fang G, Cox AJ, Davis KT, Davis BH, Li X.
    J Cell Biochem; 2010 Dec 15; 111(6):1546-55. PubMed ID: 20862710
    [Abstract] [Full Text] [Related]

  • 15. Inhibition of the phosphatidylinositol-3 kinase/Akt promotes G1 cell cycle arrest and apoptosis in Hodgkin lymphoma.
    Georgakis GV, Li Y, Rassidakis GZ, Medeiros LJ, Mills GB, Younes A.
    Br J Haematol; 2006 Feb 15; 132(4):503-11. PubMed ID: 16412023
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  • 19. Antiproliferative and proapoptotic activity of sunitinib on endothelial and anaplastic thyroid cancer cells via inhibition of Akt and ERK1/2 phosphorylation and by down-regulation of cyclin-D1.
    Di Desidero T, Fioravanti A, Orlandi P, Canu B, Giannini R, Borrelli N, Man S, Xu P, Fontanini G, Basolo F, Kerbel RS, Francia G, Danesi R, Bocci G.
    J Clin Endocrinol Metab; 2013 Sep 15; 98(9):E1465-73. PubMed ID: 23969186
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