These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Journal Abstract Search

769 related items for PubMed ID: 29188568

  • 1. Opportunities and Challenges in the Discovery of Allosteric Modulators of GPCRs.
    Bartuzi D, Kaczor AA, Matosiuk D.
    Methods Mol Biol; 2018; 1705():297-319. PubMed ID: 29188568
    [Abstract] [Full Text] [Related]

  • 2. Strategies for the identification of allosteric modulators of G-protein-coupled receptors.
    Burford NT, Watson J, Bertekap R, Alt A.
    Biochem Pharmacol; 2011 Mar 15; 81(6):691-702. PubMed ID: 21184747
    [Abstract] [Full Text] [Related]

  • 3. Leveraging allostery to improve G protein-coupled receptor (GPCR)-directed therapeutics: cannabinoid receptor 1 as discovery target.
    Janero DR, Thakur GA.
    Expert Opin Drug Discov; 2016 Dec 15; 11(12):1223-1237. PubMed ID: 27712124
    [Abstract] [Full Text] [Related]

  • 4. Current and Future Challenges in GPCR Drug Discovery.
    Topiol S.
    Methods Mol Biol; 2018 Dec 15; 1705():1-21. PubMed ID: 29188556
    [Abstract] [Full Text] [Related]

  • 5. Computational Advances for the Development of Allosteric Modulators and Bitopic Ligands in G Protein-Coupled Receptors.
    Feng Z, Hu G, Ma S, Xie XQ.
    AAPS J; 2015 Sep 15; 17(5):1080-95. PubMed ID: 25940084
    [Abstract] [Full Text] [Related]

  • 6. Allosteric Modulators of the Class A G Protein Coupled Receptors.
    Tschammer N.
    Adv Exp Med Biol; 2016 Sep 15; 917():185-207. PubMed ID: 27236557
    [Abstract] [Full Text] [Related]

  • 7. Importance of protein dynamics in the structure-based drug discovery of class A G protein-coupled receptors (GPCRs).
    Lee Y, Lazim R, Macalino SJY, Choi S.
    Curr Opin Struct Biol; 2019 Apr 15; 55():147-153. PubMed ID: 31102980
    [Abstract] [Full Text] [Related]

  • 8. Allosteric modulation of G protein-coupled receptors: a pharmacological perspective.
    Keov P, Sexton PM, Christopoulos A.
    Neuropharmacology; 2011 Jan 15; 60(1):24-35. PubMed ID: 20637785
    [Abstract] [Full Text] [Related]

  • 9. Integrated In Silico Fragment-Based Drug Design: Case Study with Allosteric Modulators on Metabotropic Glutamate Receptor 5.
    Bian Y, Feng Z, Yang P, Xie XQ.
    AAPS J; 2017 Jul 15; 19(4):1235-1248. PubMed ID: 28560482
    [Abstract] [Full Text] [Related]

  • 10. Small Molecule Allosteric Modulators of G-Protein-Coupled Receptors: Drug-Target Interactions.
    Lu S, Zhang J.
    J Med Chem; 2019 Jan 10; 62(1):24-45. PubMed ID: 29457894
    [Abstract] [Full Text] [Related]

  • 11. Harnessing allostery: a novel approach to drug discovery.
    Lu S, Li S, Zhang J.
    Med Res Rev; 2014 Nov 10; 34(6):1242-85. PubMed ID: 24827416
    [Abstract] [Full Text] [Related]

  • 12. Emerging paradigms in GPCR allostery: implications for drug discovery.
    Wootten D, Christopoulos A, Sexton PM.
    Nat Rev Drug Discov; 2013 Aug 10; 12(8):630-44. PubMed ID: 23903222
    [Abstract] [Full Text] [Related]

  • 13. Signaling within Allosteric Machines: Signal Transmission Pathways Inside G Protein-Coupled Receptors.
    Bartuzi D, Kaczor AA, Matosiuk D.
    Molecules; 2017 Jul 15; 22(7):. PubMed ID: 28714871
    [Abstract] [Full Text] [Related]

  • 14. Allosteric inhibition of g-protein coupled receptor oligomerization: strategies and challenges for drug development.
    Hurevich M, Talhami A, Shalev DE, Gilon C.
    Curr Top Med Chem; 2014 Jul 15; 14(15):1842-63. PubMed ID: 25175995
    [Abstract] [Full Text] [Related]

  • 15. Computational methods for studying G protein-coupled receptors (GPCRs).
    Kaczor AA, Rutkowska E, Bartuzi D, Targowska-Duda KM, Matosiuk D, Selent J.
    Methods Cell Biol; 2016 Jul 15; 132():359-99. PubMed ID: 26928552
    [Abstract] [Full Text] [Related]

  • 16. Bitopic Ligands and Metastable Binding Sites: Opportunities for G Protein-Coupled Receptor (GPCR) Medicinal Chemistry.
    Fronik P, Gaiser BI, Sejer Pedersen D.
    J Med Chem; 2017 May 25; 60(10):4126-4134. PubMed ID: 28140580
    [Abstract] [Full Text] [Related]

  • 17. Discovery of Novel Allosteric Modulators Targeting an Extra-Helical Binding Site of GLP-1R Using Structure- and Ligand-Based Virtual Screening.
    Zhou Q, Guo W, Dai A, Cai X, Vass M, de Graaf C, Shui W, Zhao S, Yang D, Wang MW.
    Biomolecules; 2021 Jun 23; 11(7):. PubMed ID: 34201418
    [Abstract] [Full Text] [Related]

  • 18. Allosteric Modulator Discovery: From Serendipity to Structure-Based Design.
    Lu S, He X, Ni D, Zhang J.
    J Med Chem; 2019 Jul 25; 62(14):6405-6421. PubMed ID: 30817889
    [Abstract] [Full Text] [Related]

  • 19. Allosteric modulation of GPCRs: From structural insights to in silico drug discovery.
    Persechino M, Hedderich JB, Kolb P, Hilger D.
    Pharmacol Ther; 2022 Sep 25; 237():108242. PubMed ID: 35863587
    [Abstract] [Full Text] [Related]

  • 20. Discovery of new GPCR ligands to illuminate new biology.
    Roth BL, Irwin JJ, Shoichet BK.
    Nat Chem Biol; 2017 Nov 25; 13(11):1143-1151. PubMed ID: 29045379
    [Abstract] [Full Text] [Related]

    Page: [Next] [New Search]
    of 39.