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Journal Abstract Search

328 related items for PubMed ID: 29196786

  • 1. Increased heterologous production of the antitumoral polyketide mithramycin A by engineered Streptomyces lividans TK24 strains.
    Novakova R, Núñez LE, Homerova D, Knirschova R, Feckova L, Rezuchova B, Sevcikova B, Menéndez N, Morís F, Cortés J, Kormanec J.
    Appl Microbiol Biotechnol; 2018 Jan; 102(2):857-869. PubMed ID: 29196786
    [Abstract] [Full Text] [Related]

  • 2. An efficient blue-white screening system for markerless deletions and stable integrations in Streptomyces chromosomes based on the blue pigment indigoidine biosynthetic gene bpsA.
    Rezuchova B, Homerova D, Sevcikova B, Núñez LE, Novakova R, Feckova L, Skultety L, Cortés J, Kormanec J.
    Appl Microbiol Biotechnol; 2018 Dec; 102(23):10231-10244. PubMed ID: 30259098
    [Abstract] [Full Text] [Related]

  • 3. Engineering of Streptomyces lividans for heterologous expression of secondary metabolite gene clusters.
    Ahmed Y, Rebets Y, Estévez MR, Zapp J, Myronovskyi M, Luzhetskyy A.
    Microb Cell Fact; 2020 Jan 09; 19(1):5. PubMed ID: 31918711
    [Abstract] [Full Text] [Related]

  • 4. An efficient system for stable markerless integration of large biosynthetic gene clusters into Streptomyces chromosomes.
    Csolleiova D, Knirschova R, Rezuchova B, Homerova D, Sevcikova B, Matulova M, Núñez LE, Novakova R, Feckova L, Javorova R, Cortés J, Kormanec J.
    Appl Microbiol Biotechnol; 2021 Mar 09; 105(5):2123-2137. PubMed ID: 33564923
    [Abstract] [Full Text] [Related]

  • 5. Discovery, characterization, and engineering of an advantageous Streptomyces host for heterologous expression of natural product biosynthetic gene clusters.
    Klumbys E, Xu W, Koduru L, Heng E, Wei Y, Wong FT, Zhao H, Ang EL.
    Microb Cell Fact; 2024 May 24; 23(1):149. PubMed ID: 38790014
    [Abstract] [Full Text] [Related]

  • 6. Effects of Increased NADPH Concentration by Metabolic Engineering of the Pentose Phosphate Pathway on Antibiotic Production and Sporulation in Streptomyces lividans TK24.
    Jin XM, Chang YK, Lee JH, Hong SK.
    J Microbiol Biotechnol; 2017 Oct 28; 27(10):1867-1876. PubMed ID: 28838222
    [Abstract] [Full Text] [Related]

  • 7. Expanding the Chemical Diversity of the Antitumoral Compound Mithramycin by Combinatorial Biosynthesis and Biocatalysis: The Quest for Mithralogs with Improved Therapeutic Window.
    Méndez C, González-Sabín J, Morís F, Salas JA.
    Planta Med; 2015 Oct 28; 81(15):1326-38. PubMed ID: 26393942
    [Abstract] [Full Text] [Related]

  • 8. The antitumor antibiotic mithramycin: new advanced approaches in modification and production.
    Kormanec J, Novakova R, Csolleiova D, Feckova L, Rezuchova B, Sevcikova B, Homerova D.
    Appl Microbiol Biotechnol; 2020 Sep 28; 104(18):7701-7721. PubMed ID: 32686008
    [Abstract] [Full Text] [Related]

  • 9. Heterologous reconstitution of the biosynthesis pathway for 4-demethyl-premithramycinone, the aglycon of antitumor polyketide mithramycin.
    Zabala D, Song L, Dashti Y, Challis GL, Salas JA, Méndez C.
    Microb Cell Fact; 2020 May 24; 19(1):111. PubMed ID: 32448325
    [Abstract] [Full Text] [Related]

  • 10. Heterologous production of kasugamycin, an aminoglycoside antibiotic from Streptomyces kasugaensis, in Streptomyces lividans and Rhodococcus erythropolis L-88 by constitutive expression of the biosynthetic gene cluster.
    Kasuga K, Sasaki A, Matsuo T, Yamamoto C, Minato Y, Kuwahara N, Fujii C, Kobayashi M, Agematu H, Tamura T, Komatsu M, Ishikawa J, Ikeda H, Kojima I.
    Appl Microbiol Biotechnol; 2017 May 24; 101(10):4259-4268. PubMed ID: 28243709
    [Abstract] [Full Text] [Related]

  • 11. Construction of the co-expression plasmids of fostriecin polyketide synthases and heterologous expression in Streptomyces.
    Su C, Zhao X, Qiu R, Tang L.
    Pharm Biol; 2015 Feb 24; 53(2):269-74. PubMed ID: 25427408
    [Abstract] [Full Text] [Related]

  • 12. Heterologous production of daptomycin in Streptomyces lividans.
    Penn J, Li X, Whiting A, Latif M, Gibson T, Silva CJ, Brian P, Davies J, Miao V, Wrigley SK, Baltz RH.
    J Ind Microbiol Biotechnol; 2006 Feb 24; 33(2):121-8. PubMed ID: 16261359
    [Abstract] [Full Text] [Related]

  • 13. Heterologous expression of pikromycin biosynthetic gene cluster using Streptomyces artificial chromosome system.
    Pyeon HR, Nah HJ, Kang SH, Choi SS, Kim ES.
    Microb Cell Fact; 2017 May 31; 16(1):96. PubMed ID: 28569150
    [Abstract] [Full Text] [Related]

  • 14. Heterologous production of paromamine in Streptomyces lividans TK24 using kanamycin biosynthetic genes from Streptomyces kanamyceticus ATCC12853.
    Nepal KK, Oh TJ, Sohng JK.
    Mol Cells; 2009 May 31; 27(5):601-8. PubMed ID: 19466609
    [Abstract] [Full Text] [Related]

  • 15. Mithramycin SK, a novel antitumor drug with improved therapeutic index, mithramycin SA, and demycarosyl-mithramycin SK: three new products generated in the mithramycin producer Streptomyces argillaceus through combinatorial biosynthesis.
    Remsing LL, González AM, Nur-e-Alam M, Fernández-Lozano MJ, Braña AF, Rix U, Oliveira MA, Méndez C, Salas JA, Rohr J.
    J Am Chem Soc; 2003 May 14; 125(19):5745-53. PubMed ID: 12733914
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  • 20. Insertional inactivation of mtrX and mtrY genes from the mithramycin gene cluster affects production and growth of the producer organism Streptomyces argillaceus.
    Garcia-Bernardo J, Braña AF, Méndez C, Salas JA.
    FEMS Microbiol Lett; 2000 May 01; 186(1):61-5. PubMed ID: 10779713
    [Abstract] [Full Text] [Related]

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