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Journal Abstract Search

587 related items for PubMed ID: 29197930

  • 1.
    ; . PubMed ID:
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  • 2. Mode of action framework analysis for receptor-mediated toxicity: The peroxisome proliferator-activated receptor alpha (PPARα) as a case study.
    Corton JC, Cunningham ML, Hummer BT, Lau C, Meek B, Peters JM, Popp JA, Rhomberg L, Seed J, Klaunig JE.
    Crit Rev Toxicol; 2014 Jan; 44(1):1-49. PubMed ID: 24180432
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  • 4. A human relevance investigation of PPARα-mediated key events in the hepatocarcinogenic mode of action of propaquizafop in rats.
    Strupp C, Bomann WH, Spézia F, Gervais F, Forster R, Richert L, Singh P.
    Regul Toxicol Pharmacol; 2018 Jun; 95():348-361. PubMed ID: 29626562
    [Abstract] [Full Text] [Related]

  • 5. Involvement of Peroxisome Proliferator-Activated Receptor-Alpha in Liver Tumor Production by Permethrin in the Female Mouse.
    Kondo M, Miyata K, Nagahori H, Sumida K, Osimitz TG, Cohen SM, Lake BG, Yamada T.
    Toxicol Sci; 2019 Apr 01; 168(2):572-596. PubMed ID: 30629241
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  • 6. Rodent carcinogenicity of peroxisome proliferators and issues on human relevance.
    Lai DY.
    J Environ Sci Health C Environ Carcinog Ecotoxicol Rev; 2004 May 01; 22(1):37-55. PubMed ID: 15845221
    [Abstract] [Full Text] [Related]

  • 7. Assessment of the mode of action underlying development of liver lesions in mice following oral exposure to HFPO-DA and relevance to humans.
    Heintz MM, Haws LC, Klaunig JE, Cullen JM, Thompson CM.
    Toxicol Sci; 2023 Mar 20; 192(1):15-29. PubMed ID: 36629480
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  • 8. A cancer risk assessment of di(2-ethylhexyl)phthalate: application of the new U.S. EPA Risk Assessment Guidelines.
    Doull J, Cattley R, Elcombe C, Lake BG, Swenberg J, Wilkinson C, Williams G, van Gemert M.
    Regul Toxicol Pharmacol; 1999 Jun 20; 29(3):327-57. PubMed ID: 10388618
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  • 9. An Evaluation of the Human Relevance of the Liver Tumors Observed in Female Mice Treated With Permethrin Based on Mode of Action.
    Kondo M, Kikumoto H, Osimitz TG, Cohen SM, Lake BG, Yamada T.
    Toxicol Sci; 2020 May 01; 175(1):50-63. PubMed ID: 32040184
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  • 11. Comparison of transcriptomic profiles between HFPO-DA and prototypical PPARα, PPARγ, and cytotoxic agents in mouse, rat, and pooled human hepatocytes.
    Heintz MM, Klaren WD, East AW, Haws LC, McGreal SR, Campbell RR, Thompson CM.
    Toxicol Sci; 2024 Jun 26; 200(1):165-182. PubMed ID: 38574381
    [Abstract] [Full Text] [Related]

  • 12. Modes of action and species-specific effects of di-(2-ethylhexyl)phthalate in the liver.
    Rusyn I, Peters JM, Cunningham ML.
    Crit Rev Toxicol; 2006 May 26; 36(5):459-79. PubMed ID: 16954067
    [Abstract] [Full Text] [Related]

  • 13. Peroxisome proliferator-activated receptor-α activation and excess energy burning in hepatocarcinogenesis.
    Misra P, Reddy JK.
    Biochimie; 2014 Mar 26; 98():63-74. PubMed ID: 24291192
    [Abstract] [Full Text] [Related]

  • 14. Critical evaluation of the human relevance of the mode of action for rodent liver tumor formation by activators of the constitutive androstane receptor (CAR).
    Yamada T, Cohen SM, Lake BG.
    Crit Rev Toxicol; 2021 May 26; 51(5):373-394. PubMed ID: 34264181
    [Abstract] [Full Text] [Related]

  • 15. Dose and Effect Thresholds for Early Key Events in a PPARα-Mediated Mode of Action.
    Lake AD, Wood CE, Bhat VS, Chorley BN, Carswell GK, Sey YM, Kenyon EM, Padnos B, Moore TM, Tennant AH, Schmid JE, George BJ, Ross DG, Hughes MF, Corton JC, Simmons JE, McQueen CA, Hester SD.
    Toxicol Sci; 2016 Feb 26; 149(2):312-25. PubMed ID: 26519955
    [Abstract] [Full Text] [Related]

  • 16. Assessment of the mode of action of perchloroethylene-induced mouse liver tumors.
    Klaunig JE, Bevan C, Gollapudi B.
    Toxicol Ind Health; 2024 May 26; 40(5):272-291. PubMed ID: 38523547
    [Abstract] [Full Text] [Related]

  • 17. A reexamination of the PPAR-alpha activation mode of action as a basis for assessing human cancer risks of environmental contaminants.
    Guyton KZ, Chiu WA, Bateson TF, Jinot J, Scott CS, Brown RC, Caldwell JC.
    Environ Health Perspect; 2009 Nov 26; 117(11):1664-72. PubMed ID: 20049115
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  • 18. Characterization of nuclear receptor-mediated murine hepatocarcinogenesis of the herbicide pronamide and its human relevance.
    LeBaron MJ, Rasoulpour RJ, Gollapudi BB, Sura R, Kan HL, Schisler MR, Pottenger LH, Papineni S, Eisenbrandt DL.
    Toxicol Sci; 2014 Nov 26; 142(1):74-92. PubMed ID: 25092647
    [Abstract] [Full Text] [Related]

  • 19. Role of peroxisome proliferator-activated receptor-alpha (PPARalpha) in bezafibrate-induced hepatocarcinogenesis and cholestasis.
    Hays T, Rusyn I, Burns AM, Kennett MJ, Ward JM, Gonzalez FJ, Peters JM.
    Carcinogenesis; 2005 Jan 26; 26(1):219-27. PubMed ID: 15447978
    [Abstract] [Full Text] [Related]

  • 20. Evaluation of the role of peroxisome proliferator-activated receptor alpha (PPARalpha) in mouse liver tumor induction by trichloroethylene and metabolites.
    Corton JC.
    Crit Rev Toxicol; 2008 Jan 26; 38(10):857-75. PubMed ID: 18821149
    [Abstract] [Full Text] [Related]

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