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262 related items for PubMed ID: 29219065

  • 1. Transactivation Assays that Identify Indirect and Direct Activators of Human Pregnane X Receptor (PXR, NR1I2) and Constitutive Androstane Receptor (CAR, NR1I3).
    Pinne M, Ponce E, Raucy JL.
    Drug Metab Lett; 2017; 11(2):128-137. PubMed ID: 29219065
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  • 2. Transactivation Assays to Assess Canine and Rodent Pregnane X Receptor (PXR) and Constitutive Androstane Receptor (CAR) Activation.
    Pinne M, Ponce E, Raucy JL.
    PLoS One; 2016; 11(10):e0164642. PubMed ID: 27732639
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  • 3. Evidence for triclosan-induced activation of human and rodent xenobiotic nuclear receptors.
    Paul KB, Thompson JT, Simmons SO, Vanden Heuvel JP, Crofton KM.
    Toxicol In Vitro; 2013 Oct; 27(7):2049-60. PubMed ID: 23899473
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  • 5. Human pregnane X receptor is activated by dibenzazepine carbamate-based inhibitors of constitutive androstane receptor.
    Jeske J, Windshügel B, Thasler WE, Schwab M, Burk O.
    Arch Toxicol; 2017 Jun; 91(6):2375-2390. PubMed ID: 28289823
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  • 10. Allyl isothiocyanate (AITC) inhibits pregnane X receptor (PXR) and constitutive androstane receptor (CAR) activation and protects against acetaminophen- and amiodarone-induced cytotoxicity.
    Lim YP, Cheng CH, Chen WC, Chang SY, Hung DZ, Chen JJ, Wan L, Ma WC, Lin YH, Chen CY, Yokoi T, Nakajima M, Chen CJ.
    Arch Toxicol; 2015 Jan; 89(1):57-72. PubMed ID: 25069801
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  • 12. Xenobiotic Nuclear Receptors Pregnane X Receptor and Constitutive Androstane Receptor Regulate Antiretroviral Drug Efflux Transporters at the Blood-Testis Barrier.
    Whyte-Allman SK, Hoque MT, Jenabian MA, Routy JP, Bendayan R.
    J Pharmacol Exp Ther; 2017 Dec; 363(3):324-335. PubMed ID: 28970358
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  • 13. The nuclear receptors constitutive active/androstane receptor and pregnane x receptor activate the Cyp2c55 gene in mouse liver.
    Konno Y, Kamino H, Moore R, Lih F, Tomer KB, Zeldin DC, Goldstein JA, Negishi M.
    Drug Metab Dispos; 2010 Jul; 38(7):1177-82. PubMed ID: 20371638
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  • 14. Non-coplanar polychlorinated biphenyls (PCBs) are direct agonists for the human pregnane-X receptor and constitutive androstane receptor, and activate target gene expression in a tissue-specific manner.
    Al-Salman F, Plant N.
    Toxicol Appl Pharmacol; 2012 Aug 15; 263(1):7-13. PubMed ID: 22664347
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  • 15. Induction of human CYP2A6 is mediated by the pregnane X receptor with peroxisome proliferator-activated receptor-gamma coactivator 1alpha.
    Itoh M, Nakajima M, Higashi E, Yoshida R, Nagata K, Yamazoe Y, Yokoi T.
    J Pharmacol Exp Ther; 2006 Nov 15; 319(2):693-702. PubMed ID: 16857725
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  • 16. Hepatic expression of thyroid hormone-responsive spot 14 protein is regulated by constitutive androstane receptor (NR1I3).
    Breuker C, Moreau A, Lakhal L, Tamasi V, Parmentier Y, Meyer U, Maurel P, Lumbroso S, Vilarem MJ, Pascussi JM.
    Endocrinology; 2010 Apr 15; 151(4):1653-61. PubMed ID: 20185760
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  • 17. An insulin-like growth factor 1 receptor inhibitor induces CYP3A4 expression through a pregnane X receptor-independent, noncanonical constitutive androstane receptor-related mechanism.
    Li L, Sinz MW, Zimmermann K, Wang H.
    J Pharmacol Exp Ther; 2012 Mar 15; 340(3):688-97. PubMed ID: 22171088
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  • 18. Characterization of ligand-dependent activation of bovine and pig constitutive androstane (CAR) and pregnane X receptors (PXR) with interspecies comparisons.
    Küblbeck J, Zancanella V, Prantner V, Molnár F, Squires EJ, Dacasto M, Honkakoski P, Giantin M.
    Xenobiotica; 2016 Mar 15; 46(3):200-10. PubMed ID: 26153444
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  • 19. Transcriptional regulation of human UGT1A1 gene expression: activated glucocorticoid receptor enhances constitutive androstane receptor/pregnane X receptor-mediated UDP-glucuronosyltransferase 1A1 regulation with glucocorticoid receptor-interacting protein 1.
    Sugatani J, Nishitani S, Yamakawa K, Yoshinari K, Sueyoshi T, Negishi M, Miwa M.
    Mol Pharmacol; 2005 Mar 15; 67(3):845-55. PubMed ID: 15557560
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  • 20. Ligand recognition by drug-activated nuclear receptors PXR and CAR: structural, site-directed mutagenesis and molecular modeling studies.
    Poso A, Honkakoski P.
    Mini Rev Med Chem; 2006 Aug 15; 6(8):937-47. PubMed ID: 16918499
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