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Journal Abstract Search

1340 related items for PubMed ID: 29220790

  • 1. 2-Alkoxycarbonyl-3-arylamino-5-substituted thiophenes as a novel class of antimicrotubule agents: Design, synthesis, cell growth and tubulin polymerization inhibition.
    Romagnoli R, Kimatrai Salvador M, Schiaffino Ortega S, Baraldi PG, Oliva P, Baraldi S, Lopez-Cara LC, Brancale A, Ferla S, Hamel E, Balzarini J, Liekens S, Mattiuzzo E, Basso G, Viola G.
    Eur J Med Chem; 2018 Jan 01; 143():683-698. PubMed ID: 29220790
    [Abstract] [Full Text] [Related]

  • 2. Concise synthesis and biological evaluation of 2-Aryl-3-Anilinobenzo[b]thiophene derivatives as potent apoptosis-inducing agents.
    Romagnoli R, Preti D, Hamel E, Bortolozzi R, Viola G, Brancale A, Ferla S, Morciano G, Pinton P.
    Bioorg Chem; 2021 Jul 01; 112():104919. PubMed ID: 33957538
    [Abstract] [Full Text] [Related]

  • 3. Synthesis and biological evaluation of 2-amino-3-(3',4',5'-trimethoxybenzoyl)-5-aryl thiophenes as a new class of potent antitubulin agents.
    Romagnoli R, Baraldi PG, Pavani MG, Tabrizi MA, Preti D, Fruttarolo F, Piccagli L, Jung MK, Hamel E, Borgatti M, Gambari R.
    J Med Chem; 2006 Jun 29; 49(13):3906-15. PubMed ID: 16789746
    [Abstract] [Full Text] [Related]

  • 4. Design, synthesis, and biological evaluation of novel combretastatin A-4 thio derivatives as microtubule targeting agents.
    Stefański T, Mikstacka R, Kurczab R, Dutkiewicz Z, Kucińska M, Murias M, Zielińska-Przyjemska M, Cichocki M, Teubert A, Kaczmarek M, Hogendorf A, Sobiak S.
    Eur J Med Chem; 2018 Jan 20; 144():797-816. PubMed ID: 29291446
    [Abstract] [Full Text] [Related]

  • 5. Design, synthesis and biological evaluation of 3,5-disubstituted 2-amino thiophene derivatives as a novel class of antitumor agents.
    Romagnoli R, Baraldi PG, Lopez-Cara C, Salvador MK, Preti D, Tabrizi MA, Balzarini J, Nussbaumer P, Bassetto M, Brancale A, Fu XH, Yang-Gao, Li J, Zhang SZ, Hamel E, Bortolozzi R, Basso G, Viola G.
    Bioorg Med Chem; 2014 Sep 15; 22(18):5097-109. PubMed ID: 24398384
    [Abstract] [Full Text] [Related]

  • 6. Design and discovery of new antiproliferative 1,2,4-triazin-3(2H)-ones as tubulin polymerization inhibitors targeting colchicine binding site.
    Eissa IH, Dahab MA, Ibrahim MK, Alsaif NA, Alanazi AZ, Eissa SI, Mehany ABM, Beauchemin AM.
    Bioorg Chem; 2021 Jul 15; 112():104965. PubMed ID: 34020238
    [Abstract] [Full Text] [Related]

  • 7. Synthesis and Biological Evaluation of New Antitubulin Agents Containing 2-(3',4',5'-trimethoxyanilino)-3,6-disubstituted-4,5,6,7-tetrahydrothieno[2,3-c]pyridine Scaffold.
    Romagnoli R, Prencipe F, Oliva P, Cacciari B, Balzarini J, Liekens S, Hamel E, Brancale A, Ferla S, Manfredini S, Zurlo M, Finotti A, Gambari R.
    Molecules; 2020 Apr 07; 25(7):. PubMed ID: 32272719
    [Abstract] [Full Text] [Related]

  • 8. Design, synthesis and biological evaluation of 2-alkoxycarbonyl-3-anilinoindoles as a new class of potent inhibitors of tubulin polymerization.
    Romagnoli R, Prencipe F, Oliva P, Kimatrai Salvador M, Brancale A, Ferla S, Hamel E, Viola G, Bortolozzi R, Persoons L, Balzarini J, Liekens S, Schols D.
    Bioorg Chem; 2020 Apr 07; 97():103665. PubMed ID: 32086053
    [Abstract] [Full Text] [Related]

  • 9. 3-Aryl/Heteroaryl-5-amino-1-(3',4',5'-trimethoxybenzoyl)-1,2,4-triazoles as antimicrotubule agents. Design, synthesis, antiproliferative activity and inhibition of tubulin polymerization.
    Romagnoli R, Prencipe F, Oliva P, Baraldi S, Baraldi PG, Brancale A, Ferla S, Hamel E, Bortolozzi R, Viola G.
    Bioorg Chem; 2018 Oct 07; 80():361-374. PubMed ID: 29986184
    [Abstract] [Full Text] [Related]

  • 10. Design, synthesis, in vitro and in vivo biological evaluation of 2-amino-3-aroylbenzo[b]furan derivatives as highly potent tubulin polymerization inhibitors.
    Oliva P, Romagnoli R, Manfredini S, Brancale A, Ferla S, Hamel E, Ronca R, Maccarinelli F, Giacomini A, Rruga F, Mariotto E, Viola G, Bortolozzi R.
    Eur J Med Chem; 2020 Aug 15; 200():112448. PubMed ID: 32417696
    [Abstract] [Full Text] [Related]

  • 11. Design, synthesis and biological evaluation of novel imidazole-chalcone derivatives as potential anticancer agents and tubulin polymerization inhibitors.
    Rahimzadeh Oskuei S, Mirzaei S, Reza Jafari-Nik M, Hadizadeh F, Eisvand F, Mosaffa F, Ghodsi R.
    Bioorg Chem; 2021 Jul 15; 112():104904. PubMed ID: 33933802
    [Abstract] [Full Text] [Related]

  • 12. Discovery of novel quinoline-based analogues of combretastatin A-4 as tubulin polymerisation inhibitors with apoptosis inducing activity and potent anticancer effect.
    Ibrahim TS, Hawwas MM, Malebari AM, Taher ES, Omar AM, Neamatallah T, Abdel-Samii ZK, Safo MK, Elshaier YAMM.
    J Enzyme Inhib Med Chem; 2021 Dec 15; 36(1):802-818. PubMed ID: 33730937
    [Abstract] [Full Text] [Related]

  • 13. Synthesis and biological evaluation of novel benzo[c]acridine-diones as potential anticancer agents and tubulin polymerization inhibitors.
    Behbahani FS, Tabeshpour J, Mirzaei S, Golmakaniyoon S, Tayarani-Najaran Z, Ghasemi A, Ghodsi R.
    Arch Pharm (Weinheim); 2019 Jun 15; 352(6):e1800307. PubMed ID: 31012156
    [Abstract] [Full Text] [Related]

  • 14. Design, synthesis and biological evaluation of a series of pyrano chalcone derivatives containing indole moiety as novel anti-tubulin agents.
    Wang G, Li C, He L, Lei K, Wang F, Pu Y, Yang Z, Cao D, Ma L, Chen J, Sang Y, Liang X, Xiang M, Peng A, Wei Y, Chen L.
    Bioorg Med Chem; 2014 Apr 01; 22(7):2060-79. PubMed ID: 24629450
    [Abstract] [Full Text] [Related]

  • 15. Design and synthesis of novel imidazole-chalcone derivatives as microtubule protein polymerization inhibitors to treat cervical cancer and reverse cisplatin resistance.
    Liu Z, Yang Z, Ablise M.
    Bioorg Chem; 2024 Jun 01; 147():107310. PubMed ID: 38583249
    [Abstract] [Full Text] [Related]

  • 16. Synthesis and evaluation of new 2-chloro-4-aminopyrimidine and 2,6-dimethyl-4-aminopyrimidine derivatives as tubulin polymerization inhibitors.
    Xu S, An B, Li Y, Luo X, Li X, Jia X.
    Bioorg Med Chem Lett; 2018 Jun 01; 28(10):1769-1775. PubMed ID: 29673981
    [Abstract] [Full Text] [Related]

  • 17. 9-Benzylidene-naphtho[2,3-b]thiophen-4-ones as novel antimicrotubule agents-synthesis, antiproliferative activity, and inhibition of tubulin polymerization.
    Zuse A, Schmidt P, Baasner S, Böhm KJ, Müller K, Gerlach M, Günther EG, Unger E, Prinz H.
    J Med Chem; 2006 Dec 28; 49(26):7816-25. PubMed ID: 17181164
    [Abstract] [Full Text] [Related]

  • 18. Design, synthesis and biological evaluation of novel vicinal diaryl-substituted 1H-Pyrazole analogues of combretastatin A-4 as highly potent tubulin polymerization inhibitors.
    Romagnoli R, Oliva P, Salvador MK, Camacho ME, Padroni C, Brancale A, Ferla S, Hamel E, Ronca R, Grillo E, Bortolozzi R, Rruga F, Mariotto E, Viola G.
    Eur J Med Chem; 2019 Nov 01; 181():111577. PubMed ID: 31400707
    [Abstract] [Full Text] [Related]

  • 19. Design, synthesis and bioevaluation of 6-aryl-1-(3,4,5-trimethoxyphenyl)-1H-benzo[d]imidazoles as tubulin polymerization inhibitors.
    Liu R, Huang M, Zhang S, Li L, Li M, Sun J, Wu L, Guan Q, Zhang W.
    Eur J Med Chem; 2021 Dec 15; 226():113826. PubMed ID: 34571171
    [Abstract] [Full Text] [Related]

  • 20. Thiazolidinone Constraint Combretastatin Analogs as Novel Antitubulin Agents: Design, Synthesis, Biological Evaluation and Docking Studies.
    Sharma S, Gupta MK, Saxena AK, Bedi PM.
    Anticancer Agents Med Chem; 2017 Dec 15; 17(2):230-240. PubMed ID: 27141882
    [Abstract] [Full Text] [Related]

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