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Journal Abstract Search

494 related items for PubMed ID: 29223096

  • 1. Discovery of aliphatic-chain hydroxamates containing indole derivatives with potent class I histone deacetylase inhibitory activities.
    Chao SW, Chen LC, Yu CC, Liu CY, Lin TE, Guh JH, Wang CY, Chen CY, Hsu KC, Huang WJ.
    Eur J Med Chem; 2018 Jan 01; 143():792-805. PubMed ID: 29223096
    [Abstract] [Full Text] [Related]

  • 2. Design, synthesis, and biological evaluation of indole-based hydroxamic acid derivatives as histone deacetylase inhibitors.
    Jiang BE, Hu J, Liu H, Liu Z, Wen Y, Liu M, Zhang HK, Pang X, Yu LF.
    Eur J Med Chem; 2022 Jan 05; 227():113893. PubMed ID: 34656899
    [Abstract] [Full Text] [Related]

  • 3. Discovery and preliminary evaluation of 2-aminobenzamide and hydroxamate derivatives containing 1,2,4-oxadiazole moiety as potent histone deacetylase inhibitors.
    Cai J, Wei H, Hong KH, Wu X, Cao M, Zong X, Li L, Sun C, Chen J, Ji M.
    Eur J Med Chem; 2015 Jan 05; 96():1-13. PubMed ID: 25874326
    [Abstract] [Full Text] [Related]

  • 4. Design, synthesis and biological evaluation of novel hydroxamates and 2-aminobenzamides as potent histone deacetylase inhibitors and antitumor agents.
    Xie R, Yao Y, Tang P, Chen G, Liu X, Yun F, Cheng C, Wu X, Yuan Q.
    Eur J Med Chem; 2017 Jul 07; 134():1-12. PubMed ID: 28391133
    [Abstract] [Full Text] [Related]

  • 5. Amide-based derivatives of β-alanine hydroxamic acid as histone deacetylase inhibitors: attenuation of potency through resonance effects.
    Liao V, Liu T, Codd R.
    Bioorg Med Chem Lett; 2012 Oct 01; 22(19):6200-4. PubMed ID: 22932316
    [Abstract] [Full Text] [Related]

  • 6. Design, Synthesis and Biological Evaluation of Novel Coumarin-Based Hydroxamate Derivatives as Histone Deacetylase (Hdac) Inhibitors with Antitumor Activities.
    Yang F, Zhao N, Song J, Zhu K, Jiang CS, Shan P, Zhang H.
    Molecules; 2019 Jul 15; 24(14):. PubMed ID: 31311163
    [Abstract] [Full Text] [Related]

  • 7. Synthesis and Investigation of Therapeutic Potential of Isoform-Specific HDAC8 Inhibitors for the Treatment of Cutaneous T Cell Lymphoma.
    Umamaheswari A, Puratchikody A, Hari N.
    Anticancer Agents Med Chem; 2019 Jul 15; 19(7):916-934. PubMed ID: 30836926
    [Abstract] [Full Text] [Related]

  • 8. Quinazoline-Based Hydroxamic Acids: Design, Synthesis, and Evaluation of Histone Deacetylase Inhibitory Effects and Cytotoxicity.
    Hieu DT, Anh DT, Hai PT, Huong LT, Park EJ, Choi JE, Kang JS, Dung PTP, Han SB, Nam NH.
    Chem Biodivers; 2018 Jun 15; 15(6):e1800027. PubMed ID: 29667768
    [Abstract] [Full Text] [Related]

  • 9. 1-Aroylindoline-hydroxamic acids as anticancer agents, inhibitors of HSP90 and HDAC.
    Ojha R, Huang HL, HuangFu WC, Wu YW, Nepali K, Lai MJ, Su CJ, Sung TY, Chen YL, Pan SL, Liou JP.
    Eur J Med Chem; 2018 Apr 25; 150():667-677. PubMed ID: 29567459
    [Abstract] [Full Text] [Related]

  • 10. Novel Hydroxamic Acids Incorporating 1-((1H-1,2,3-Triazol-4-yl)methyl)- 3-substituted-2-oxoindolines: Synthesis, Biological Evaluation and SAR Analysis.
    Dung DTM, Huan NV, Cam DM, Hieu DC, Hai PT, Huong LT, Kim J, Choi JE, Kang JS, Han SB, Nam NH.
    Med Chem; 2018 Apr 25; 14(8):831-850. PubMed ID: 29807520
    [Abstract] [Full Text] [Related]

  • 11. Structure-activity relationship and mechanistic studies for a series of cinnamyl hydroxamate histone deacetylase inhibitors.
    Tavares MT, de Almeida LC, Kronenberger T, Monteiro Ferreira G, Fujii de Divitiis T, Franco Zannini Junqueira Toledo M, Mariko Aymoto Hassimotto N, Agostinho Machado-Neto J, Veras Costa-Lotufo L, Parise-Filho R.
    Bioorg Med Chem; 2021 Apr 01; 35():116085. PubMed ID: 33668008
    [Abstract] [Full Text] [Related]

  • 12. Design, synthesis and preliminary bioactivity studies of 1,3,4-thiadiazole hydroxamic acid derivatives as novel histone deacetylase inhibitors.
    Guan P, Sun F, Hou X, Wang F, Yi F, Xu W, Fang H.
    Bioorg Med Chem; 2012 Jun 15; 20(12):3865-72. PubMed ID: 22579621
    [Abstract] [Full Text] [Related]

  • 13. Quinazolin-4(3H)-one-Based Hydroxamic Acids: Design, Synthesis and Evaluation of Histone Deacetylase Inhibitory Effects and Cytotoxicity.
    Hieu DT, Anh DT, Hai PT, Thuan NT, Huong LT, Park EJ, Young Ji A, Soon Kang J, Phuong Dung PT, Han SB, Nam NH.
    Chem Biodivers; 2019 Apr 15; 16(4):e1800502. PubMed ID: 30653817
    [Abstract] [Full Text] [Related]

  • 14. Design and synthesis of a new generation of substituted purine hydroxamate analogs as histone deacetylase inhibitors.
    Liu R, Wang J, Tang W, Fang H.
    Bioorg Med Chem; 2016 Apr 01; 24(7):1446-54. PubMed ID: 26907204
    [Abstract] [Full Text] [Related]

  • 15. New benzothiazole/thiazole-containing hydroxamic acids as potent histone deacetylase inhibitors and antitumor agents.
    Tung TT, Oanh DT, Dung PT, Hue VT, Park SH, Han BW, Kim Y, Hong JT, Han SB, Nam NH.
    Med Chem; 2013 Dec 01; 9(8):1051-7. PubMed ID: 23521008
    [Abstract] [Full Text] [Related]

  • 16. A hybrid of thiazolidinone with the hydroxamate scaffold for developing novel histone deacetylase inhibitors with antitumor activities.
    Yang F, Peng S, Li Y, Su L, Peng Y, Wu J, Chen H, Liu M, Yi Z, Chen Y.
    Org Biomol Chem; 2016 Feb 07; 14(5):1727-35. PubMed ID: 26732459
    [Abstract] [Full Text] [Related]

  • 17. Design, synthesis and anticancer evaluation of acridine hydroxamic acid derivatives as dual Topo and HDAC inhibitors.
    Chen J, Li D, Li W, Yin J, Zhang Y, Yuan Z, Gao C, Liu F, Jiang Y.
    Bioorg Med Chem; 2018 Aug 07; 26(14):3958-3966. PubMed ID: 29954683
    [Abstract] [Full Text] [Related]

  • 18. Design, Synthesis and Biological Evaluation of Novel N-hydroxyheptanamides Incorporating 6-hydroxy-2-methylquinazolin-4(3H)-ones as Histone Deacetylase Inhibitors and Cytotoxic Agents.
    Minh NV, Thanh NT, Lien HT, Anh DTP, Cuong HD, Nam NH, Hai PT, Minh-Ngoc L, Le-Thi-Thu H, Chinh LV, Vu TK.
    Anticancer Agents Med Chem; 2019 Aug 07; 19(12):1543-1557. PubMed ID: 31267876
    [Abstract] [Full Text] [Related]

  • 19. Novel N-hydroxybenzamides incorporating 2-oxoindoline with unexpected potent histone deacetylase inhibitory effects and antitumor cytotoxicity.
    Huong TT, Dung DT, Huan NV, Cuong LV, Hai PT, Huong LT, Kim J, Kim YG, Han SB, Nam NH.
    Bioorg Chem; 2017 Apr 07; 71():160-169. PubMed ID: 28196602
    [Abstract] [Full Text] [Related]

  • 20. Novel 3-substituted-2-oxoindoline-based N-hydroxypropenamides as histone deacetylase inhibitors and antitumor agents.
    Dung do TM, Dung PT, Oanh DT, Hai PT, Huong le TT, Loi VD, Hahn H, Han BW, Kim J, Han SB, Nam NH.
    Med Chem; 2015 Apr 07; 11(8):725-35. PubMed ID: 26133355
    [Abstract] [Full Text] [Related]

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