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Journal Abstract Search


206 related items for PubMed ID: 29258818

  • 1. Remodeling of HIV-1 Nef Structure by Src-Family Kinase Binding.
    Moroco JA, Alvarado JJ, Staudt RP, Shi H, Wales TE, Smithgall TE, Engen JR.
    J Mol Biol; 2018 Feb 02; 430(3):310-321. PubMed ID: 29258818
    [Abstract] [Full Text] [Related]

  • 2. Interaction with the Src homology (SH3-SH2) region of the Src-family kinase Hck structures the HIV-1 Nef dimer for kinase activation and effector recruitment.
    Alvarado JJ, Tarafdar S, Yeh JI, Smithgall TE.
    J Biol Chem; 2014 Oct 10; 289(41):28539-53. PubMed ID: 25122770
    [Abstract] [Full Text] [Related]

  • 3. Subtle Dynamic Changes Accompany Hck Activation by HIV-1 Nef and are Reversed by an Antiretroviral Kinase Inhibitor.
    Wales TE, Hochrein JM, Morgan CR, Emert-Sedlak LA, Smithgall TE, Engen JR.
    Biochemistry; 2015 Oct 20; 54(41):6382-91. PubMed ID: 26440750
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  • 7. The human immunodeficiency virus type 1 Nef protein binds the Src-related tyrosine kinase Lck SH2 domain through a novel phosphotyrosine independent mechanism.
    Dutartre H, Harris M, Olive D, Collette Y.
    Virology; 1998 Aug 01; 247(2):200-11. PubMed ID: 9705913
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  • 8. The crystal structure of HIV-1 Nef protein bound to the Fyn kinase SH3 domain suggests a role for this complex in altered T cell receptor signaling.
    Arold S, Franken P, Strub MP, Hoh F, Benichou S, Benarous R, Dumas C.
    Structure; 1997 Oct 15; 5(10):1361-72. PubMed ID: 9351809
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  • 9. Activation of the Src-family tyrosine kinase Hck by SH3 domain displacement.
    Moarefi I, LaFevre-Bernt M, Sicheri F, Huse M, Lee CH, Kuriyan J, Miller WT.
    Nature; 1997 Feb 13; 385(6617):650-3. PubMed ID: 9024665
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  • 10. RT loop flexibility enhances the specificity of Src family SH3 domains for HIV-1 Nef.
    Arold S, O'Brien R, Franken P, Strub MP, Hoh F, Dumas C, Ladbury JE.
    Biochemistry; 1998 Oct 20; 37(42):14683-91. PubMed ID: 9778343
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  • 11. The HIV-1 protein Nef activates the Tec family kinase Btk by stabilizing an intermolecular SH3-SH2 domain interaction.
    Aryal M, Lin D, Regan K, Du S, Shi H, Alvarado JJ, Ilina TV, Andreotti AH, Smithgall TE.
    Sci Signal; 2022 Sep 20; 15(752):eabn8359. PubMed ID: 36126115
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  • 12. HIV-2 and SIV nef proteins target different Src family SH3 domains than does HIV-1 Nef because of a triple amino acid substitution.
    Collette Y, Arold S, Picard C, Janvier K, Benichou S, Benarous R, Olive D, Dumas C.
    J Biol Chem; 2000 Feb 11; 275(6):4171-6. PubMed ID: 10660579
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  • 14. Structure, function, and inhibitor targeting of HIV-1 Nef-effector kinase complexes.
    Staudt RP, Alvarado JJ, Emert-Sedlak LA, Shi H, Shu ST, Wales TE, Engen JR, Smithgall TE.
    J Biol Chem; 2020 Oct 30; 295(44):15158-15171. PubMed ID: 32862141
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  • 15. Crystal structure of the Src family kinase Hck SH3-SH2 linker regulatory region supports an SH3-dominant activation mechanism.
    Alvarado JJ, Betts L, Moroco JA, Smithgall TE, Yeh JI.
    J Biol Chem; 2010 Nov 12; 285(46):35455-61. PubMed ID: 20810664
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  • 16. SH3-mediated Hck tyrosine kinase activation and fibroblast transformation by the Nef protein of HIV-1.
    Briggs SD, Sharkey M, Stevenson M, Smithgall TE.
    J Biol Chem; 1997 Jul 18; 272(29):17899-902. PubMed ID: 9218412
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  • 17. Neutron Reflectometry and Molecular Simulations Demonstrate HIV-1 Nef Homodimer Formation on Model Lipid Bilayers.
    Heinrich F, Thomas CE, Alvarado JJ, Eells R, Thomas A, Doucet M, Whitlatch KN, Aryal M, Lösche M, Smithgall TE.
    J Mol Biol; 2023 Apr 15; 435(8):168009. PubMed ID: 36773691
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  • 18. The accessory factor Nef links HIV-1 to Tec/Btk kinases in an Src homology 3 domain-dependent manner.
    Tarafdar S, Poe JA, Smithgall TE.
    J Biol Chem; 2014 May 30; 289(22):15718-28. PubMed ID: 24722985
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  • 19. Evolutionary plasticity of SH3 domain binding by Nef proteins of the HIV-1/SIVcpz lentiviral lineage.
    Zhao Z, Fagerlund R, Tossavainen H, Hopfensperger K, Lotke R, Srinivasachar Badarinarayan S, Kirchhoff F, Permi P, Sato K, Sauter D, Saksela K.
    PLoS Pathog; 2021 Nov 30; 17(11):e1009728. PubMed ID: 34780577
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  • 20. SH3 domains with high affinity and engineered ligand specificities targeted to HIV-1 Nef.
    Hiipakka M, Poikonen K, Saksela K.
    J Mol Biol; 1999 Nov 12; 293(5):1097-106. PubMed ID: 10547288
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