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Journal Abstract Search

306 related items for PubMed ID: 29268127

  • 1. Design, synthesis and biological evaluation of 1, 4-dihydro indeno[1,2-c] pyrazole linked oxindole analogues as potential anticancer agents targeting tubulin and inducing p53 dependent apoptosis.
    Khan I, Garikapati KR, Shaik AB, Makani VKK, Rahim A, Shareef MA, Reddy VG, Pal-Bhadra M, Kamal A, Kumar CG.
    Eur J Med Chem; 2018 Jan 20; 144():104-115. PubMed ID: 29268127
    [Abstract] [Full Text] [Related]

  • 2. Design and synthesis of pyrazole-oxindole conjugates targeting tubulin polymerization as new anticancer agents.
    Kamal A, Shaik AB, Jain N, Kishor C, Nagabhushana A, Supriya B, Bharath Kumar G, Chourasiya SS, Suresh Y, Mishra RK, Addlagatta A.
    Eur J Med Chem; 2015 Mar 06; 92():501-13. PubMed ID: 25599948
    [Abstract] [Full Text] [Related]

  • 3. Design, Synthesis, and Biological Evaluation of 1-Methyl-1,4-dihydroindeno[1,2-c]pyrazole Analogues as Potential Anticancer Agents Targeting Tubulin Colchicine Binding Site.
    Liu YN, Wang JJ, Ji YT, Zhao GD, Tang LQ, Zhang CM, Guo XL, Liu ZP.
    J Med Chem; 2016 Jun 09; 59(11):5341-55. PubMed ID: 27172319
    [Abstract] [Full Text] [Related]

  • 4. Synthesis, biological evaluation and molecular docking of benzimidazole grafted benzsulfamide-containing pyrazole ring derivatives as novel tubulin polymerization inhibitors.
    Wang YT, Shi TQ, Zhu HL, Liu CH.
    Bioorg Med Chem; 2019 Feb 01; 27(3):502-515. PubMed ID: 30606674
    [Abstract] [Full Text] [Related]

  • 5. Design, synthesis and biological evaluation of novel pyrazoline-containing derivatives as potential tubulin assembling inhibitors.
    Qin YJ, Li YJ, Jiang AQ, Yang MR, Zhu QZ, Dong H, Zhu HL.
    Eur J Med Chem; 2015 Apr 13; 94():447-57. PubMed ID: 25828827
    [Abstract] [Full Text] [Related]

  • 6. Design and synthesis of pyrazole/isoxazole linked arylcinnamides as tubulin polymerization inhibitors and potential antiproliferative agents.
    Kamal A, Shaik AB, Rao BB, Khan I, Bharath Kumar G, Jain N.
    Org Biomol Chem; 2015 Oct 28; 13(40):10162-78. PubMed ID: 26303171
    [Abstract] [Full Text] [Related]

  • 7. Synthesis of imidazo-thiadiazole linked indolinone conjugates and evaluated their microtubule network disrupting and apoptosis inducing ability.
    Narasimha Rao MP, Nagaraju B, Kovvuri J, Polepalli S, Alavala S, Vishnuvardhan MVPS, Swapna P, Nimbarte VD, Lakshmi JK, Jain N, Kamal A.
    Bioorg Chem; 2018 Feb 28; 76():420-436. PubMed ID: 29275261
    [Abstract] [Full Text] [Related]

  • 8. Synthesis and Biological Evaluation of 1-Methyl-1H-indole-Pyrazoline Hybrids as Potential Tubulin Polymerization Inhibitors.
    Zhang YL, Qin YJ, Tang DJ, Yang MR, Li BY, Wang YT, Cai HY, Wang BZ, Zhu HL.
    ChemMedChem; 2016 Jul 05; 11(13):1446-58. PubMed ID: 27159418
    [Abstract] [Full Text] [Related]

  • 9. Discovery, biological evaluation, structure-activity relationships and mechanism of action of pyrazolo[3,4-b]pyridin-6-one derivatives as a new class of anticancer agents.
    Guo Q, Luo Y, Zhai S, Jiang Z, Zhao C, Xu J, Wang L.
    Org Biomol Chem; 2019 Jun 26; 17(25):6201-6214. PubMed ID: 31179474
    [Abstract] [Full Text] [Related]

  • 10. Synthesis and biological evaluation of imidazo[2,1-b][1,3,4]thiadiazole-linked oxindoles as potent tubulin polymerization inhibitors.
    Kamal A, Rao MP, Das P, Swapna P, Polepalli S, Nimbarte VD, Mullagiri K, Kovvuri J, Jain N.
    ChemMedChem; 2014 Jul 26; 9(7):1463-75. PubMed ID: 24715721
    [Abstract] [Full Text] [Related]

  • 11. Novel nicotinoyl pyrazoline derivates bearing N-methyl indole moiety as antitumor agents: Design, synthesis and evaluation.
    Chen K, Zhang YL, Fan J, Ma X, Qin YJ, Zhu HL.
    Eur J Med Chem; 2018 Aug 05; 156():722-737. PubMed ID: 30041136
    [Abstract] [Full Text] [Related]

  • 12. Design, synthesis and biological evaluation of a novel tubulin inhibitor 7a3 targeting the colchicine binding site.
    Lai Q, Wang Y, Wang R, Lai W, Tang L, Tao Y, Liu Y, Zhang R, Huang L, Xiang H, Zeng S, Gou L, Chen H, Yao Y, Yang J.
    Eur J Med Chem; 2018 Aug 05; 156():162-179. PubMed ID: 30006162
    [Abstract] [Full Text] [Related]

  • 13. Design, synthesis, biological evaluation, and 3D-QSAR analysis of podophyllotoxin-dioxazole combination as tubulin targeting anticancer agents.
    Wang ZZ, Sun WX, Wang X, Zhang YH, Qiu HY, Qi JL, Pang YJ, Lu GH, Wang XM, Yu FG, Yang YH.
    Chem Biol Drug Des; 2017 Aug 05; 90(2):236-243. PubMed ID: 28079286
    [Abstract] [Full Text] [Related]

  • 14. Synthesis and biological evaluation of novel indole-pyrimidine hybrids bearing morpholine and thiomorpholine moieties.
    Diao PC, Li Q, Hu MJ, Ma YF, You WW, Hong KH, Zhao PL.
    Eur J Med Chem; 2017 Jul 07; 134():110-118. PubMed ID: 28410492
    [Abstract] [Full Text] [Related]

  • 15. Synthesis and biological evaluation of (1-aryl-1H-pyrazol-4-yl) (3,4,5-trimethoxyphenyl)methanone derivatives as tubulin inhibitors.
    Zhai M, Wang L, Liu S, Wang L, Yan P, Wang J, Zhang J, Guo H, Guan Q, Bao K, Wu Y, Zhang W.
    Eur J Med Chem; 2018 Aug 05; 156():137-147. PubMed ID: 30006160
    [Abstract] [Full Text] [Related]

  • 16. Design and synthesis of aminostilbene-arylpropenones as tubulin polymerization inhibitors.
    Kamal A, Kumar GB, Polepalli S, Shaik AB, Reddy VS, Reddy MK, Reddy ChR, Mahesh R, Kapure JS, Jain N.
    ChemMedChem; 2014 Nov 05; 9(11):2565-79. PubMed ID: 25146959
    [Abstract] [Full Text] [Related]

  • 17. Synthesis of a terphenyl substituted 4-aza-2,3-didehydropodophyllotoxin analogues as inhibitors of tubulin polymerization and apoptosis inducers.
    Kamal A, Tamboli JR, Nayak VL, Adil SF, Vishnuvardhan MV, Ramakrishna S.
    Bioorg Med Chem; 2014 May 01; 22(9):2714-23. PubMed ID: 24721832
    [Abstract] [Full Text] [Related]

  • 18. Synthesis of benzo[d]imidazo[2,1-b]thiazole-chalcone conjugates as microtubule targeting and apoptosis inducing agents.
    Sultana F, Reddy Bonam S, Reddy VG, Nayak VL, Akunuri R, Rani Routhu S, Alarifi A, Halmuthur MSK, Kamal A.
    Bioorg Chem; 2018 Feb 01; 76():1-12. PubMed ID: 29102724
    [Abstract] [Full Text] [Related]

  • 19. Synthesis and biological evaluation of novel benzo[c]acridine-diones as potential anticancer agents and tubulin polymerization inhibitors.
    Behbahani FS, Tabeshpour J, Mirzaei S, Golmakaniyoon S, Tayarani-Najaran Z, Ghasemi A, Ghodsi R.
    Arch Pharm (Weinheim); 2019 Jun 01; 352(6):e1800307. PubMed ID: 31012156
    [Abstract] [Full Text] [Related]

  • 20. Synthesis and biological evaluation of novel pyrano[3,2-c]carbazole derivatives as anti-tumor agents inducing apoptosis via tubulin polymerization inhibition.
    Padmaja P, Koteswara Rao G, Indrasena A, Subba Reddy BV, Patel N, Shaik AB, Reddy N, Dubey PK, Bhadra MP.
    Org Biomol Chem; 2015 Feb 07; 13(5):1404-14. PubMed ID: 25467166
    [Abstract] [Full Text] [Related]

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