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Journal Abstract Search

776 related items for PubMed ID: 29269047

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  • 2. Hepatic insulin resistance in ob/ob mice involves increases in ceramide, aPKC activity, and selective impairment of Akt-dependent FoxO1 phosphorylation.
    Sajan MP, Ivey RA, Lee MC, Farese RV.
    J Lipid Res; 2015 Jan; 56(1):70-80. PubMed ID: 25395359
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  • 3. BMI-related progression of atypical PKC-dependent aberrations in insulin signaling through IRS-1, Akt, FoxO1 and PGC-1α in livers of obese and type 2 diabetic humans.
    Sajan MP, Ivey RA, Farese RV.
    Metabolism; 2015 Nov; 64(11):1454-65. PubMed ID: 26386696
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  • 4. Akt-dependent phosphorylation of hepatic FoxO1 is compartmentalized on a WD40/ProF scaffold and is selectively inhibited by aPKC in early phases of diet-induced obesity.
    Sajan MP, Acevedo-Duncan ME, Standaert ML, Ivey RA, Lee M, Farese RV.
    Diabetes; 2014 Aug; 63(8):2690-701. PubMed ID: 24705403
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  • 7. Spexin alleviates insulin resistance and inhibits hepatic gluconeogenesis via the FoxO1/PGC-1α pathway in high-fat-diet-induced rats and insulin resistant cells.
    Gu L, Ding X, Wang Y, Gu M, Zhang J, Yan S, Li N, Song Z, Yin J, Lu L, Peng Y.
    Int J Biol Sci; 2019 Aug; 15(13):2815-2829. PubMed ID: 31853220
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  • 8. Baicalin ameliorates hepatic insulin resistance and gluconeogenic activity through inhibition of p38 MAPK/PGC-1α pathway.
    Fang P, Sun Y, Gu X, Shi M, Bo P, Zhang Z, Bu L.
    Phytomedicine; 2019 Nov; 64():153074. PubMed ID: 31473580
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  • 9. The adipokine sFRP4 induces insulin resistance and lipogenesis in the liver.
    Hörbelt T, Knebel B, Fahlbusch P, Barbosa D, de Wiza DH, Van de Velde F, Van Nieuwenhove Y, Lapauw B, Thoresen GH, Al-Hasani H, Müller-Wieland D, Ouwens DM, Kotzka J.
    Biochim Biophys Acta Mol Basis Dis; 2019 Oct 01; 1865(10):2671-2684. PubMed ID: 31336149
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  • 12. PKCλ haploinsufficiency prevents diabetes by a mechanism involving alterations in hepatic enzymes.
    Sajan MP, Ivey RA, Lee M, Mastorides S, Jurczak MJ, Samuels VT, Shulman GI, Braun U, Leitges M, Farese RV.
    Mol Endocrinol; 2014 Jul 01; 28(7):1097-107. PubMed ID: 24877563
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  • 13. Role of atypical protein kinase C in activation of sterol regulatory element binding protein-1c and nuclear factor kappa B (NFkappaB) in liver of rodents used as a model of diabetes, and relationships to hyperlipidaemia and insulin resistance.
    Sajan MP, Standaert ML, Rivas J, Miura A, Kanoh Y, Soto J, Taniguchi CM, Kahn CR, Farese RV.
    Diabetologia; 2009 Jun 01; 52(6):1197-207. PubMed ID: 19357831
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  • 14. PGC-1α functions as a co-suppressor of XBP1s to regulate glucose metabolism.
    Lee J, Salazar Hernández MA, Auen T, Mucka P, Lee J, Ozcan U.
    Mol Metab; 2018 Jan 01; 7():119-131. PubMed ID: 29129613
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  • 16. ALAS1 gene expression is down-regulated by Akt-mediated phosphorylation and nuclear exclusion of FOXO1 by vanadate in diabetic mice.
    Oliveri LM, Davio C, Batlle AM, Gerez EN.
    Biochem J; 2012 Mar 01; 442(2):303-10. PubMed ID: 22070747
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  • 18. Insulin-regulated hepatic gluconeogenesis through FOXO1-PGC-1alpha interaction.
    Puigserver P, Rhee J, Donovan J, Walkey CJ, Yoon JC, Oriente F, Kitamura Y, Altomonte J, Dong H, Accili D, Spiegelman BM.
    Nature; 2003 May 29; 423(6939):550-5. PubMed ID: 12754525
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  • 19. FoxO1 regulates multiple metabolic pathways in the liver: effects on gluconeogenic, glycolytic, and lipogenic gene expression.
    Zhang W, Patil S, Chauhan B, Guo S, Powell DR, Le J, Klotsas A, Matika R, Xiao X, Franks R, Heidenreich KA, Sajan MP, Farese RV, Stolz DB, Tso P, Koo SH, Montminy M, Unterman TG.
    J Biol Chem; 2006 Apr 14; 281(15):10105-17. PubMed ID: 16492665
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