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103 related items for PubMed ID: 29269410

  • 1. Epidermal Growth Factor Represses Constitutive Androstane Receptor Expression in Primary Human Hepatocytes and Favors Regulation by Pregnane X Receptor.
    de Boussac H, Gondeau C, Briolotti P, Duret C, Treindl F, Römer M, Fabre JM, Herrero A, Ramos J, Maurel P, Templin M, Gerbal-Chaloin S, Daujat-Chavanieu M.
    Drug Metab Dispos; 2018 Mar; 46(3):223-236. PubMed ID: 29269410
    [Abstract] [Full Text] [Related]

  • 2. Comparison of the effects of sodium phenobarbital in wild type and humanized constitutive androstane receptor (CAR)/pregnane X receptor (PXR) mice and in cultured mouse, rat and human hepatocytes.
    Haines C, Elcombe BM, Chatham LR, Vardy A, Higgins LG, Elcombe CR, Lake BG.
    Toxicology; 2018 Mar 01; 396-397():23-32. PubMed ID: 29425889
    [Abstract] [Full Text] [Related]

  • 3. Identification of a novel human constitutive androstane receptor (CAR) agonist and its use in the identification of CAR target genes.
    Maglich JM, Parks DJ, Moore LB, Collins JL, Goodwin B, Billin AN, Stoltz CA, Kliewer SA, Lambert MH, Willson TM, Moore JT.
    J Biol Chem; 2003 May 09; 278(19):17277-83. PubMed ID: 12611900
    [Abstract] [Full Text] [Related]

  • 4. Genome-wide analysis of human constitutive androstane receptor (CAR) transcriptome in wild-type and CAR-knockout HepaRG cells.
    Li D, Mackowiak B, Brayman TG, Mitchell M, Zhang L, Huang SM, Wang H.
    Biochem Pharmacol; 2015 Nov 01; 98(1):190-202. PubMed ID: 26275810
    [Abstract] [Full Text] [Related]

  • 5. Genomewide comparison of the inducible transcriptomes of nuclear receptors CAR, PXR and PPARα in primary human hepatocytes.
    Kandel BA, Thomas M, Winter S, Damm G, Seehofer D, Burk O, Schwab M, Zanger UM.
    Biochim Biophys Acta; 2016 Sep 01; 1859(9):1218-1227. PubMed ID: 26994748
    [Abstract] [Full Text] [Related]

  • 6. Development of an in vitro high content imaging assay for quantitative assessment of CAR-dependent mouse, rat, and human primary hepatocyte proliferation.
    Soldatow V, Peffer RC, Trask OJ, Cowie DE, Andersen ME, LeCluyse E, Deisenroth C.
    Toxicol In Vitro; 2016 Oct 01; 36():224-237. PubMed ID: 27530964
    [Abstract] [Full Text] [Related]

  • 7. Phenobarbital Induces SLC13A5 Expression through Activation of PXR but Not CAR in Human Primary Hepatocytes.
    Li Z, Li L, Heyward S, Men S, Xu M, Sueyoshi T, Wang H.
    Cells; 2021 Dec 01; 10(12):. PubMed ID: 34943889
    [Abstract] [Full Text] [Related]

  • 8. Metabonomic studies on human hepatocyte in primary culture.
    Croixmarie V, Umbdenstock T, Cloarec O, Moreau A, Pascussi JM, Parmentier Y, Boursier-Neyret C, Walther B.
    Methods Mol Biol; 2010 Dec 01; 640():355-74. PubMed ID: 20645062
    [Abstract] [Full Text] [Related]

  • 9. Regulation of gender-dependent CYP2A expression in pigs: involvement of androgens and CAR.
    Gillberg M, Skaanild MT, Friis C.
    Basic Clin Pharmacol Toxicol; 2006 May 01; 98(5):480-7. PubMed ID: 16635107
    [Abstract] [Full Text] [Related]

  • 10. Phosphorylated Nuclear Receptor CAR Forms a Homodimer To Repress Its Constitutive Activity for Ligand Activation.
    Shizu R, Osabe M, Perera L, Moore R, Sueyoshi T, Negishi M.
    Mol Cell Biol; 2017 May 15; 37(10):. PubMed ID: 28265001
    [Abstract] [Full Text] [Related]

  • 11. Hepatic expression of thyroid hormone-responsive spot 14 protein is regulated by constitutive androstane receptor (NR1I3).
    Breuker C, Moreau A, Lakhal L, Tamasi V, Parmentier Y, Meyer U, Maurel P, Lumbroso S, Vilarem MJ, Pascussi JM.
    Endocrinology; 2010 Apr 15; 151(4):1653-61. PubMed ID: 20185760
    [Abstract] [Full Text] [Related]

  • 12. Phenobarbital regulates nuclear expression of HNF-4alpha in mouse and rat hepatocytes independent of CAR and PXR.
    Bell AW, Michalopoulos GK.
    Hepatology; 2006 Jul 15; 44(1):186-94. PubMed ID: 16799975
    [Abstract] [Full Text] [Related]

  • 13. CITCO Directly Binds to and Activates Human Pregnane X Receptor.
    Lin W, Bwayi M, Wu J, Li Y, Chai SC, Huber AD, Chen T.
    Mol Pharmacol; 2020 Mar 15; 97(3):180-190. PubMed ID: 31882411
    [Abstract] [Full Text] [Related]

  • 14. Establishing Transcriptional Signatures to Differentiate PXR-, CAR-, and AhR-Mediated Regulation of Drug Metabolism and Transport Genes in Cryopreserved Human Hepatocytes.
    Moscovitz JE, Kalgutkar AS, Nulick K, Johnson N, Lin Z, Goosen TC, Weng Y.
    J Pharmacol Exp Ther; 2018 May 15; 365(2):262-271. PubMed ID: 29440451
    [Abstract] [Full Text] [Related]

  • 15. Activation of the Constitutive Androstane Receptor induces hepatic lipogenesis and regulates Pnpla3 gene expression in a LXR-independent way.
    Marmugi A, Lukowicz C, Lasserre F, Montagner A, Polizzi A, Ducheix S, Goron A, Gamet-Payrastre L, Gerbal-Chaloin S, Pascussi JM, Moldes M, Pineau T, Guillou H, Mselli-Lakhal L.
    Toxicol Appl Pharmacol; 2016 Jul 15; 303():90-100. PubMed ID: 27180240
    [Abstract] [Full Text] [Related]

  • 16. Phenobarbital indirectly activates the constitutive active androstane receptor (CAR) by inhibition of epidermal growth factor receptor signaling.
    Mutoh S, Sobhany M, Moore R, Perera L, Pedersen L, Sueyoshi T, Negishi M.
    Sci Signal; 2013 May 07; 6(274):ra31. PubMed ID: 23652203
    [Abstract] [Full Text] [Related]

  • 17. Old dance with a new partner: EGF receptor as the phenobarbital receptor mediating Cyp2B expression.
    Meyer SA, Jirtle RL.
    Sci Signal; 2013 May 07; 6(274):pe16. PubMed ID: 23652202
    [Abstract] [Full Text] [Related]

  • 18. Chrysin, baicalein and galangin are indirect activators of the human constitutive androstane receptor (CAR).
    Carazo Fernández A, Smutny T, Hyrsová L, Berka K, Pavek P.
    Toxicol Lett; 2015 Mar 04; 233(2):68-77. PubMed ID: 25625231
    [Abstract] [Full Text] [Related]

  • 19. Metformin represses drug-induced expression of CYP2B6 by modulating the constitutive androstane receptor signaling.
    Yang H, Garzel B, Heyward S, Moeller T, Shapiro P, Wang H.
    Mol Pharmacol; 2014 Feb 04; 85(2):249-60. PubMed ID: 24252946
    [Abstract] [Full Text] [Related]

  • 20. Integrated comparison of drug-related and drug-induced ultra performance liquid chromatography/mass spectrometry metabonomic profiles using human hepatocyte cultures.
    Croixmarie V, Umbdenstock T, Cloarec O, Moreau A, Pascussi JM, Boursier-Neyret C, Walther B.
    Anal Chem; 2009 Aug 01; 81(15):6061-9. PubMed ID: 19588937
    [Abstract] [Full Text] [Related]

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