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Journal Abstract Search

285 related items for PubMed ID: 29277460

  • 1. Aconitum alkaloids, the major components of Aconitum species, affect expression of multidrug resistance-associated protein 2 and breast cancer resistance protein by activating the Nrf2-mediated signalling pathway.
    Wu JJ, Zhu YF, Guo ZZ, Lou YM, He SG, Guan Y, Zhu LJ, Liu ZQ, Lu LL, Liu L.
    Phytomedicine; 2018 May 15; 44():87-97. PubMed ID: 29277460
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  • 2. Multidrug resistance-associated protein 2 is involved in the efflux of Aconitum alkaloids determined by MRP2-MDCKII cells.
    Dai P, Zhu L, Yang X, Zhao M, Shi J, Wang Y, Lu L, Liu Z.
    Life Sci; 2015 Apr 15; 127():66-72. PubMed ID: 25744397
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  • 3. The role of efflux transporters on the transport of highly toxic aconitine, mesaconitine, hypaconitine, and their hydrolysates, as determined in cultured Caco-2 and transfected MDCKII cells.
    Ye L, Yang X, Yang Z, Gao S, Yin T, Liu W, Wang F, Hu M, Liu Z.
    Toxicol Lett; 2013 Feb 04; 216(2-3):86-99. PubMed ID: 23200901
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  • 4. Astragali radix and its main bioactive compounds activate the Nrf2-mediated signaling pathway to induce P-glycoprotein and breast cancer resistance protein.
    Lou Y, Guo Z, Zhu Y, Zhang G, Wang Y, Qi X, Lu L, Liu Z, Wu J.
    J Ethnopharmacol; 2019 Jan 10; 228():82-91. PubMed ID: 30243825
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  • 6. Induction of P-glycoprotein expression and activity by Aconitum alkaloids: Implication for clinical drug-drug interactions.
    Wu J, Lin N, Li F, Zhang G, He S, Zhu Y, Ou R, Li N, Liu S, Feng L, Liu L, Liu Z, Lu L.
    Sci Rep; 2016 May 03; 6():25343. PubMed ID: 27139035
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  • 7. Differential selectivity of efflux transporter inhibitors in Caco-2 and MDCK-MDR1 monolayers: a strategy to assess the interaction of a new chemical entity with P-gp, BCRP, and MRP2.
    Mease K, Sane R, Podila L, Taub ME.
    J Pharm Sci; 2012 May 03; 101(5):1888-97. PubMed ID: 22359351
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  • 10. Mdr1a, Bcrp and Mrp2 regulate the efficacy and toxicity of mesaconitine and hypaconitine by altering their tissue accumulation and in vivo residence.
    Li X, Ou X, Luo G, Ou X, Xie Y, Ying M, Qu W, Zuo H, Qi X, Wang Y, Liu Z, Zhu L.
    Toxicol Appl Pharmacol; 2020 Dec 15; 409():115332. PubMed ID: 33171190
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