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Journal Abstract Search

846 related items for PubMed ID: 29280968

  • 1. Design, Synthesis and Cytotoxic Evaluation of Novel Chalcone Derivatives Bearing Triazolo[4,3-a]-quinoxaline Moieties as Potent Anticancer Agents with Dual EGFR Kinase and Tubulin Polymerization Inhibitory Effects.
    Alswah M, Bayoumi AH, Elgamal K, Elmorsy A, Ihmaid S, Ahmed HEA.
    Molecules; 2017 Dec 27; 23(1):. PubMed ID: 29280968
    [Abstract] [Full Text] [Related]

  • 2. Design, Synthesis, In Vitro Anti-cancer Activity, ADMET Profile and Molecular Docking of Novel Triazolo[3,4-a]phthalazine Derivatives Targeting VEGFR-2 Enzyme.
    El-Helby AA, Sakr H, Ayyad RRA, El-Adl K, Ali MM, Khedr F.
    Anticancer Agents Med Chem; 2018 Dec 27; 18(8):1184-1196. PubMed ID: 29651967
    [Abstract] [Full Text] [Related]

  • 3. Design, synthesis and biological evaluation of a series of pyrano chalcone derivatives containing indole moiety as novel anti-tubulin agents.
    Wang G, Li C, He L, Lei K, Wang F, Pu Y, Yang Z, Cao D, Ma L, Chen J, Sang Y, Liang X, Xiang M, Peng A, Wei Y, Chen L.
    Bioorg Med Chem; 2014 Apr 01; 22(7):2060-79. PubMed ID: 24629450
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  • 4. Synthesis and Preclinical Evaluation of Indole Triazole Conjugates as Microtubule Targeting Agents that are Effective against MCF-7 Breast Cancer Cell Lines.
    Yele V, Pindiprolu SKSS, Sana S, Ramamurty DSVNM, Madasi JRK, Vadlamani S.
    Anticancer Agents Med Chem; 2021 Apr 01; 21(8):1047-1055. PubMed ID: 32981511
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  • 5. Design, synthesis and biological evaluation of novel chalcone derivatives as antitubulin agents.
    Zhang H, Liu JJ, Sun J, Yang XH, Zhao TT, Lu X, Gong HB, Zhu HL.
    Bioorg Med Chem; 2012 May 15; 20(10):3212-8. PubMed ID: 22503741
    [Abstract] [Full Text] [Related]

  • 6. Design, synthesis and biological evaluation of novel imidazole-chalcone derivatives as potential anticancer agents and tubulin polymerization inhibitors.
    Rahimzadeh Oskuei S, Mirzaei S, Reza Jafari-Nik M, Hadizadeh F, Eisvand F, Mosaffa F, Ghodsi R.
    Bioorg Chem; 2021 Jul 15; 112():104904. PubMed ID: 33933802
    [Abstract] [Full Text] [Related]

  • 7. New bis([1,2,4]triazolo)[4,3-a:3',4'-c]quinoxaline derivatives as VEGFR-2 inhibitors and apoptosis inducers: Design, synthesis, in silico studies, and anticancer evaluation.
    Alanazi MM, Mahdy HA, Alsaif NA, Obaidullah AJ, Alkahtani HM, Al-Mehizia AA, Alsubaie SM, Dahab MA, Eissa IH.
    Bioorg Chem; 2021 Jul 15; 112():104949. PubMed ID: 34023640
    [Abstract] [Full Text] [Related]

  • 8. Synthesis, Anticancer Activity and Molecular Modeling Studies of Novel Chalcone Derivatives Containing Indole and Naphthalene Moieties as Tubulin Polymerization Inhibitors.
    Wang G, Peng Z, Li Y.
    Chem Pharm Bull (Tokyo); 2019 Jul 01; 67(7):725-728. PubMed ID: 30982797
    [Abstract] [Full Text] [Related]

  • 9. Design, synthesis, molecular docking and anti-proliferative evaluations of [1,2,4]triazolo[4,3-a]quinoxaline derivatives as DNA intercalators and Topoisomerase II inhibitors.
    El-Adl K, El-Helby AA, Sakr H, Elwan A.
    Bioorg Chem; 2020 Dec 01; 105():104399. PubMed ID: 33113414
    [Abstract] [Full Text] [Related]

  • 10. Novel 2-[thio]acetamide linked quinazoline/1,2,4-triazole/chalcone hybrids: Design, synthesis, and anticancer activity as EGFR inhibitors and apoptotic inducers.
    Abdelkhalek AS, Kothayer H, Soltan MK, Ibrahim SM, Elbaramawi SS.
    Arch Pharm (Weinheim); 2024 Jul 01; 357(7):e2300627. PubMed ID: 38593298
    [Abstract] [Full Text] [Related]

  • 11. Synthesis of different heterocycles-linked chalcone conjugates as cytotoxic agents and tubulin polymerization inhibitors.
    Shankaraiah N, Nekkanti S, Brahma UR, Praveen Kumar N, Deshpande N, Prasanna D, Senwar KR, Jaya Lakshmi U.
    Bioorg Med Chem; 2017 Sep 01; 25(17):4805-4816. PubMed ID: 28774575
    [Abstract] [Full Text] [Related]

  • 12. Synthesis, EGFR Inhibition and Anti-cancer Activity of New 3,6-dimethyl-1-phenyl-4-(substituted-methoxy)pyrazolo[3,4-d] pyrimidine Derivatives.
    Bakr RB, Mehany ABM, Abdellatif KRA.
    Anticancer Agents Med Chem; 2017 Sep 01; 17(10):1389-1400. PubMed ID: 28270084
    [Abstract] [Full Text] [Related]

  • 13. Design, synthesis and molecular modeling of new 4-phenylcoumarin derivatives as tubulin polymerization inhibitors targeting MCF-7 breast cancer cells.
    Batran RZ, Kassem AF, Abbas EMH, Elseginy SA, Mounier MM.
    Bioorg Med Chem; 2018 Jul 23; 26(12):3474-3490. PubMed ID: 29793751
    [Abstract] [Full Text] [Related]

  • 14. Design and synthesis of novel imidazole-chalcone derivatives as microtubule protein polymerization inhibitors to treat cervical cancer and reverse cisplatin resistance.
    Liu Z, Yang Z, Ablise M.
    Bioorg Chem; 2024 Jun 23; 147():107310. PubMed ID: 38583249
    [Abstract] [Full Text] [Related]

  • 15. The Design and Development of Potent Small Molecules as Anticancer Agents Targeting EGFR TK and Tubulin Polymerization.
    Ihmaid S, Ahmed HEA, Zayed MF.
    Int J Mol Sci; 2018 Jan 30; 19(2):. PubMed ID: 29385728
    [Abstract] [Full Text] [Related]

  • 16. Design, synthesis, biological evaluation and molecular docking studies of new chalcone derivatives containing diaryl ether moiety as potential anticancer agents and tubulin polymerization inhibitors.
    Wang G, Liu W, Gong Z, Huang Y, Li Y, Peng Z.
    Bioorg Chem; 2020 Jan 30; 95():103565. PubMed ID: 31927336
    [Abstract] [Full Text] [Related]

  • 17. Novel [1,2,4]triazolo[1,5-a]pyrimidine derivatives as potent antitubulin agents: Design, multicomponent synthesis and antiproliferative activities.
    Yang F, Yu LZ, Diao PC, Jian XE, Zhou MF, Jiang CS, You WW, Ma WF, Zhao PL.
    Bioorg Chem; 2019 Nov 30; 92():103260. PubMed ID: 31525523
    [Abstract] [Full Text] [Related]

  • 18. Design, synthesis, and molecular docking of novel pyrazole-chalcone analogs of lonazolac as 5-LOX, iNOS and tubulin polymerization inhibitors with potential anticancer and anti-inflammatory activities.
    Ahmed AHH, Mohamed MFA, Allam RM, Nafady A, Mohamed SK, Gouda AE, Beshr EAM.
    Bioorg Chem; 2022 Dec 30; 129():106171. PubMed ID: 36166898
    [Abstract] [Full Text] [Related]

  • 19. Discovery of new quinolines as potent colchicine binding site inhibitors: design, synthesis, docking studies, and anti-proliferative evaluation.
    Hagras M, El Deeb MA, Elzahabi HSA, Elkaeed EB, Mehany ABM, Eissa IH.
    J Enzyme Inhib Med Chem; 2021 Dec 30; 36(1):640-658. PubMed ID: 33588683
    [Abstract] [Full Text] [Related]

  • 20. Synthesis, biological evaluation, and molecular docking analysis of phenstatin based indole linked chalcones as anticancer agents and tubulin polymerization inhibitors.
    Kode J, Kovvuri J, Nagaraju B, Jadhav S, Barkume M, Sen S, Kasinathan NK, Chaudhari P, Mohanty BS, Gour J, Sigalapalli DK, Ganesh Kumar C, Pradhan T, Banerjee M, Kamal A.
    Bioorg Chem; 2020 Dec 30; 105():104447. PubMed ID: 33207276
    [Abstract] [Full Text] [Related]

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