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Journal Abstract Search

601 related items for PubMed ID: 29289887

  • 21. Synthesis and biological evaluation of pyrazolone analogues as potential anti-inflammatory agents targeting cyclooxygenases and 5-lipoxygenase.
    Shabaan MA, Kamal AM, Faggal SI, Elsahar AE, Mohamed KO.
    Arch Pharm (Weinheim); 2020 Apr; 353(4):e1900308. PubMed ID: 32031284
    [Abstract] [Full Text] [Related]

  • 22. Synthesis, biological evaluation, docking study and ulcerogenicity profiling of some novel quinoline-2-carboxamides as dual COXs/LOX inhibitors endowed with anti-inflammatory activity.
    Abdelrahman MH, Youssif BGM, Abdelgawad MA, Abdelazeem AH, Ibrahim HM, Moustafa AEGA, Treamblu L, Bukhari SNA.
    Eur J Med Chem; 2017 Feb 15; 127():972-985. PubMed ID: 27837994
    [Abstract] [Full Text] [Related]

  • 23. Design, synthesis, and biological evaluation of new pyrazoloquinazoline derivatives as dual COX-2/5-LOX inhibitors.
    Shaaban MA, Kamal AM, Faggal SI, Farag NA, Aborehab NM, Elsahar AE, Mohamed KO.
    Arch Pharm (Weinheim); 2020 Nov 15; 353(11):e2000027. PubMed ID: 32696514
    [Abstract] [Full Text] [Related]

  • 24. Design, synthesis of 2,3-disubstitued 4(3H)-quinazolinone derivatives as anti-inflammatory and analgesic agents: COX-1/2 inhibitory activities and molecular docking studies.
    Abdel-Aziz AA, Abou-Zeid LA, ElTahir KE, Mohamed MA, Abu El-Enin MA, El-Azab AS.
    Bioorg Med Chem; 2016 Aug 15; 24(16):3818-28. PubMed ID: 27344214
    [Abstract] [Full Text] [Related]

  • 25. Click chemistry synthesis, biological evaluation and docking study of some novel 2'-hydroxychalcone-triazole hybrids as potent anti-inflammatory agents.
    Boshra AN, Abdu-Allah HHM, Mohammed AF, Hayallah AM.
    Bioorg Chem; 2020 Jan 15; 95():103505. PubMed ID: 31901755
    [Abstract] [Full Text] [Related]

  • 26. Synthesis, anti-inflammatory, analgesic and COX-1/2 inhibition activities of anilides based on 5,5-diphenylimidazolidine-2,4-dione scaffold: Molecular docking studies.
    Abdel-Aziz AA, El-Azab AS, Abou-Zeid LA, ElTahir KE, Abdel-Aziz NI, Ayyad RR, Al-Obaid AM.
    Eur J Med Chem; 2016 Jun 10; 115():121-31. PubMed ID: 26999325
    [Abstract] [Full Text] [Related]

  • 27. 1,2,3-triazole tethered Indole-3-glyoxamide derivatives as multiple inhibitors of 5-LOX, COX-2 & tubulin: Their anti-proliferative & anti-inflammatory activity.
    Naaz F, Preeti Pallavi MC, Shafi S, Mulakayala N, Shahar Yar M, Sampath Kumar HM.
    Bioorg Chem; 2018 Dec 10; 81():1-20. PubMed ID: 30081353
    [Abstract] [Full Text] [Related]

  • 28. Benzimidazole scaffold based hybrid molecules for various inflammatory targets: Synthesis and evaluation.
    Kaur G, Silakari O.
    Bioorg Chem; 2018 Oct 10; 80():24-35. PubMed ID: 29864685
    [Abstract] [Full Text] [Related]

  • 29. Design, synthesis and evaluation of some pyrazolo[3,4-d]pyrimidines as anti-inflammatory agents.
    Tageldin GN, Fahmy SM, Ashour HM, Khalil MA, Nassra RA, Labouta IM.
    Bioorg Chem; 2018 Aug 10; 78():358-371. PubMed ID: 29627656
    [Abstract] [Full Text] [Related]

  • 30. Novel 1,2,4-triazine-quinoline hybrids: The privileged scaffolds as potent multi-target inhibitors of LPS-induced inflammatory response via dual COX-2 and 15-LOX inhibition.
    Ghanim AM, Rezq S, Ibrahim TS, Romero DG, Kothayer H.
    Eur J Med Chem; 2021 Jul 05; 219():113457. PubMed ID: 33892270
    [Abstract] [Full Text] [Related]

  • 31. Synthesis, anti-inflammatory activity and COX-1/COX-2 inhibition of novel substituted cyclic imides. Part 1: Molecular docking study.
    Abdel-Aziz AA, ElTahir KE, Asiri YA.
    Eur J Med Chem; 2011 May 05; 46(5):1648-55. PubMed ID: 21388719
    [Abstract] [Full Text] [Related]

  • 32. Novel class of benzimidazole-thiazole hybrids: The privileged scaffolds of potent anti-inflammatory activity with dual inhibition of cyclooxygenase and 15-lipoxygenase enzymes.
    Maghraby MT, Abou-Ghadir OMF, Abdel-Moty SG, Ali AY, Salem OIA.
    Bioorg Med Chem; 2020 Apr 01; 28(7):115403. PubMed ID: 32127262
    [Abstract] [Full Text] [Related]

  • 33. Synthesis, antitumour activities and molecular docking of thiocarboxylic acid ester-based NSAID scaffolds: COX-2 inhibition and mechanistic studies.
    El-Azab AS, Abdel-Aziz AA, Abou-Zeid LA, El-Husseiny WM, El Morsy AM, El-Gendy MA, El-Sayed MA.
    J Enzyme Inhib Med Chem; 2018 Dec 01; 33(1):989-998. PubMed ID: 29806488
    [Abstract] [Full Text] [Related]

  • 34. Design and synthesis of quinazolinone derivatives as anti-inflammatory agents: pharmacophore modeling and 3D QSAR studies.
    Chaitanya P, Reddy GD, Varun G, Srikanth LM, Prasad VV, Ravindernath A.
    Med Chem; 2014 Dec 01; 10(7):711-23. PubMed ID: 24286396
    [Abstract] [Full Text] [Related]

  • 35. Dual COX-2 and 15-LOX inhibition study of novel 4-arylidine-2-mercapto-1-phenyl-1H-imidazolidin-5(4H)-ones: Design, synthesis, docking, and anti-inflammatory activity.
    Osman NA, Soltan MK, Rezq S, Flaherty J, Romero DG, Abdelkhalek AS.
    Arch Pharm (Weinheim); 2024 May 01; 357(5):e2300615. PubMed ID: 38315093
    [Abstract] [Full Text] [Related]

  • 36.
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  • 37. Tailored quinoline hybrids as promising COX-2/15-LOX dual inhibitors endowed with diverse safety profile: Design, synthesis, SAR, and histopathological study.
    Hegazy ME, Taher ES, Ghiaty AH, Bayoumi AH.
    Bioorg Chem; 2024 Apr 01; 145():107244. PubMed ID: 38428284
    [Abstract] [Full Text] [Related]

  • 38. Ruthenium(ii) arene NSAID complexes: inhibition of cyclooxygenase and antiproliferative activity against cancer cell lines.
    Mandal P, Kundu BK, Vyas K, Sabu V, Helen A, Dhankhar SS, Nagaraja CM, Bhattacherjee D, Bhabak KP, Mukhopadhyay S.
    Dalton Trans; 2018 Jan 02; 47(2):517-527. PubMed ID: 29235601
    [Abstract] [Full Text] [Related]

  • 39. Synthesis, biological evaluation and molecular modeling study of pyrazole derivatives as selective COX-2 inhibitors and anti-inflammatory agents.
    Tewari AK, Singh VP, Yadav P, Gupta G, Singh A, Goel RK, Shinde P, Mohan CG.
    Bioorg Chem; 2014 Oct 02; 56():8-15. PubMed ID: 24893208
    [Abstract] [Full Text] [Related]

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