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254 related items for PubMed ID: 29301852

  • 1. Protein Kinase G Activation Reverses Oxidative Stress and Restores Osteoblast Function and Bone Formation in Male Mice With Type 1 Diabetes.
    Kalyanaraman H, Schwaerzer G, Ramdani G, Castillo F, Scott BT, Dillmann W, Sah RL, Casteel DE, Pilz RB.
    Diabetes; 2018 Apr; 67(4):607-623. PubMed ID: 29301852
    [Abstract] [Full Text] [Related]

  • 2. The bradykinin-cGMP-PKG pathway augments insulin sensitivity via upregulation of MAPK phosphatase-5 and inhibition of JNK.
    Frigolet ME, Thomas G, Beard K, Lu H, Liu L, Fantus IG.
    Am J Physiol Endocrinol Metab; 2017 Sep 01; 313(3):E321-E334. PubMed ID: 28679626
    [Abstract] [Full Text] [Related]

  • 3. Cinaciguat in combination with insulin induces a favorable effect on implant osseointegration in type 2 diabetic rats.
    Jia T, Wang YN, Zhang J, Hao X, Zhang D, Xu X.
    Biomed Pharmacother; 2019 Oct 01; 118():109216. PubMed ID: 31319371
    [Abstract] [Full Text] [Related]

  • 4. Soluble guanylate cyclase as a novel treatment target for osteoporosis.
    Joshua J, Schwaerzer GK, Kalyanaraman H, Cory E, Sah RL, Li M, Vaida F, Boss GR, Pilz RB.
    Endocrinology; 2014 Dec 01; 155(12):4720-30. PubMed ID: 25188528
    [Abstract] [Full Text] [Related]

  • 5. Essential roles of the nitric oxide (no)/cGMP/protein kinase G type-Iα (PKG-Iα) signaling pathway and the atrial natriuretic peptide (ANP)/cGMP/PKG-Iα autocrine loop in promoting proliferation and cell survival of OP9 bone marrow stromal cells.
    Wong JC, Fiscus RR.
    J Cell Biochem; 2011 Mar 01; 112(3):829-39. PubMed ID: 21328456
    [Abstract] [Full Text] [Related]

  • 6. Sambucus williamsii Hance maintains bone homeostasis in hyperglycemia-induced osteopenia by reversing oxidative stress via cGMP/PKG signal transduction.
    Shen YW, Cheng YA, Li Y, Li Z, Yang BY, Li X.
    Phytomedicine; 2023 Feb 01; 110():154607. PubMed ID: 36610352
    [Abstract] [Full Text] [Related]

  • 7. Nitric oxide activates PI3-K and MAPK signalling pathways in human and rat vascular smooth muscle cells: influence of insulin resistance and oxidative stress.
    Doronzo G, Viretto M, Russo I, Mattiello L, Di Martino L, Cavalot F, Anfossi G, Trovati M.
    Atherosclerosis; 2011 May 01; 216(1):44-53. PubMed ID: 21316056
    [Abstract] [Full Text] [Related]

  • 8. Type II cGMP-dependent protein kinase mediates osteoblast mechanotransduction.
    Rangaswami H, Marathe N, Zhuang S, Chen Y, Yeh JC, Frangos JA, Boss GR, Pilz RB.
    J Biol Chem; 2009 May 29; 284(22):14796-808. PubMed ID: 19282289
    [Abstract] [Full Text] [Related]

  • 9. The soluble guanylate cyclase activator cinaciguat prevents cardiac dysfunction in a rat model of type-1 diabetes mellitus.
    Mátyás C, Németh BT, Oláh A, Hidi L, Birtalan E, Kellermayer D, Ruppert M, Korkmaz-Icöz S, Kökény G, Horváth EM, Szabó G, Merkely B, Radovits T.
    Cardiovasc Diabetol; 2015 Oct 31; 14():145. PubMed ID: 26520063
    [Abstract] [Full Text] [Related]

  • 10. Icariin stimulates the osteogenic differentiation of rat bone marrow stromal cells via activating the PI3K-AKT-eNOS-NO-cGMP-PKG.
    Zhai YK, Guo XY, Ge BF, Zhen P, Ma XN, Zhou J, Ma HP, Xian CJ, Chen KM.
    Bone; 2014 Sep 31; 66():189-98. PubMed ID: 24956021
    [Abstract] [Full Text] [Related]

  • 11. Protein kinase G2 activation restores Wnt signaling and bone mass in glucocorticoid-induced osteoporosis in mice.
    Pal China S, Kalyanaraman H, Zhuang S, Cabriales JA, Sah RL, Pilz RB.
    JCI Insight; 2024 Jun 17; 9(14):. PubMed ID: 38885330
    [Abstract] [Full Text] [Related]

  • 12. Sinusoidal electromagnetic field stimulates rat osteoblast differentiation and maturation via activation of NO-cGMP-PKG pathway.
    Cheng G, Zhai Y, Chen K, Zhou J, Han G, Zhu R, Ming L, Song P, Wang J.
    Nitric Oxide; 2011 Oct 30; 25(3):316-25. PubMed ID: 21664476
    [Abstract] [Full Text] [Related]

  • 13. Pro-survival effects of 17β-estradiol on osteocytes are mediated by nitric oxide/cGMP via differential actions of cGMP-dependent protein kinases I and II.
    Marathe N, Rangaswami H, Zhuang S, Boss GR, Pilz RB.
    J Biol Chem; 2012 Jan 06; 287(2):978-88. PubMed ID: 22117068
    [Abstract] [Full Text] [Related]

  • 14. A Novel, Direct NO Donor Regulates Osteoblast and Osteoclast Functions and Increases Bone Mass in Ovariectomized Mice.
    Kalyanaraman H, Ramdani G, Joshua J, Schall N, Boss GR, Cory E, Sah RL, Casteel DE, Pilz RB.
    J Bone Miner Res; 2017 Jan 06; 32(1):46-59. PubMed ID: 27391172
    [Abstract] [Full Text] [Related]

  • 15. Effect of nitric oxide-cGMP-dependent protein kinase activation on advanced glycation end-product-induced proliferation in renal fibroblasts.
    Huang JS, Chuang LY, Guh JY, Chen CJ, Yang YL, Chiang TA, Hung MY, Liao TN.
    J Am Soc Nephrol; 2005 Aug 06; 16(8):2318-29. PubMed ID: 15958724
    [Abstract] [Full Text] [Related]

  • 16. Empagliflozin prevents cardiomyopathy via sGC-cGMP-PKG pathway in type 2 diabetes mice.
    Xue M, Li T, Wang Y, Chang Y, Cheng Y, Lu Y, Liu X, Xu L, Li X, Yu X, Sun B, Chen L.
    Clin Sci (Lond); 2019 Aug 15; 133(15):1705-1720. PubMed ID: 31337673
    [Abstract] [Full Text] [Related]

  • 17. Activation of soluble guanylyl cyclase signalling with cinaciguat improves impaired kidney function in diabetic mice.
    Harloff M, Prüschenk S, Seifert R, Schlossmann J.
    Br J Pharmacol; 2022 Jun 15; 179(11):2460-2475. PubMed ID: 33651375
    [Abstract] [Full Text] [Related]

  • 18. Resistance to the nitric oxide/cyclic guanosine 5'-monophosphate/protein kinase G pathway in vascular smooth muscle cells from the obese Zucker rat, a classical animal model of insulin resistance: role of oxidative stress.
    Russo I, Del Mese P, Doronzo G, Mattiello L, Viretto M, Bosia A, Anfossi G, Trovati M.
    Endocrinology; 2008 Apr 15; 149(4):1480-9. PubMed ID: 18079207
    [Abstract] [Full Text] [Related]

  • 19. Guanosine 3',5'-cyclic monophosphate (cGMP)/cGMP-dependent protein kinase induce interleukin-6 transcription in osteoblasts.
    Broderick KE, Zhang T, Rangaswami H, Zeng Y, Zhao X, Boss GR, Pilz RB.
    Mol Endocrinol; 2007 May 15; 21(5):1148-62. PubMed ID: 17341596
    [Abstract] [Full Text] [Related]

  • 20. Cinaciguat, a novel activator of soluble guanylate cyclase, protects against ischemia/reperfusion injury: role of hydrogen sulfide.
    Salloum FN, Das A, Samidurai A, Hoke NN, Chau VQ, Ockaili RA, Stasch JP, Kukreja RC.
    Am J Physiol Heart Circ Physiol; 2012 Mar 15; 302(6):H1347-54. PubMed ID: 22268103
    [Abstract] [Full Text] [Related]

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