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Journal Abstract Search

865 related items for PubMed ID: 29306206

  • 1. Design, synthesis, biological evaluation and cocrystal structures with tubulin of chiral β-lactam bridged combretastatin A-4 analogues as potent antitumor agents.
    Zhou P, Liang Y, Zhang H, Jiang H, Feng K, Xu P, Wang J, Wang X, Ding K, Luo C, Liu M, Wang Y.
    Eur J Med Chem; 2018 Jan 20; 144():817-842. PubMed ID: 29306206
    [Abstract] [Full Text] [Related]

  • 2. Potent Antitumor Activities and Structure Basis of the Chiral β-Lactam Bridged Analogue of Combretastatin A-4 Binding to Tubulin.
    Zhou P, Liu Y, Zhou L, Zhu K, Feng K, Zhang H, Liang Y, Jiang H, Luo C, Liu M, Wang Y.
    J Med Chem; 2016 Nov 23; 59(22):10329-10334. PubMed ID: 27805821
    [Abstract] [Full Text] [Related]

  • 3. Design, synthesis, and biological evaluation of novel combretastatin A-4 thio derivatives as microtubule targeting agents.
    Stefański T, Mikstacka R, Kurczab R, Dutkiewicz Z, Kucińska M, Murias M, Zielińska-Przyjemska M, Cichocki M, Teubert A, Kaczmarek M, Hogendorf A, Sobiak S.
    Eur J Med Chem; 2018 Jan 20; 144():797-816. PubMed ID: 29291446
    [Abstract] [Full Text] [Related]

  • 4. Design, synthesis and biological evaluation of a series of pyrano chalcone derivatives containing indole moiety as novel anti-tubulin agents.
    Wang G, Li C, He L, Lei K, Wang F, Pu Y, Yang Z, Cao D, Ma L, Chen J, Sang Y, Liang X, Xiang M, Peng A, Wei Y, Chen L.
    Bioorg Med Chem; 2014 Apr 01; 22(7):2060-79. PubMed ID: 24629450
    [Abstract] [Full Text] [Related]

  • 5. Design, synthesis, and biological evaluation of hydantoin bridged analogues of combretastatin A-4 as potential anticancer agents.
    Zhang M, Liang YR, Li H, Liu MM, Wang Y.
    Bioorg Med Chem; 2017 Dec 15; 25(24):6623-6634. PubMed ID: 29126741
    [Abstract] [Full Text] [Related]

  • 6. Synthesis and Biological Evaluations of 1,2-Diaryl Pyrroles as Analogues of Combretastatin A-4.
    Sun J, Chen L, Liu C, Wang Z, Zuo D, Pan J, Qi H, Bao K, Wu Y, Zhang W.
    Chem Biol Drug Des; 2015 Dec 15; 86(6):1541-7. PubMed ID: 26202587
    [Abstract] [Full Text] [Related]

  • 7. Synthesis and evaluation of azetidinone analogues of combretastatin A-4 as tubulin targeting agents.
    O'Boyle NM, Carr M, Greene LM, Bergin O, Nathwani SM, McCabe T, Lloyd DG, Zisterer DM, Meegan MJ.
    J Med Chem; 2010 Dec 23; 53(24):8569-84. PubMed ID: 21080725
    [Abstract] [Full Text] [Related]

  • 8. Lead identification of conformationally restricted β-lactam type combretastatin analogues: synthesis, antiproliferative activity and tubulin targeting effects.
    Carr M, Greene LM, Knox AJ, Lloyd DG, Zisterer DM, Meegan MJ.
    Eur J Med Chem; 2010 Dec 23; 45(12):5752-66. PubMed ID: 20933304
    [Abstract] [Full Text] [Related]

  • 9. Synthesis of Combretastatin-A4 Carboxamidest that Mimic Sulfonyl Piperazines by a Molecular Hybridization Approach: in vitro Cytotoxicity Evaluation and Inhibition of Tubulin Polymerization.
    Jadala C, Sathish M, Anchi P, Tokala R, Lakshmi UJ, Reddy VG, Shankaraiah N, Godugu C, Kamal A.
    ChemMedChem; 2019 Dec 17; 14(24):2052-2060. PubMed ID: 31674147
    [Abstract] [Full Text] [Related]

  • 10. Design, Synthesis and Antitumor Activity of Novel link-bridge and B-Ring Modified Combretastatin A-4 (CA-4) Analogues as Potent Antitubulin Agents.
    Duan YT, Man RJ, Tang DJ, Yao YF, Tao XX, Yu C, Liang XY, Makawana JA, Zou MJ, Wang ZC, Zhu HL.
    Sci Rep; 2016 May 03; 6():25387. PubMed ID: 27138035
    [Abstract] [Full Text] [Related]

  • 11. Design, Synthesis, and Biological Evaluation of 1-Methyl-1,4-dihydroindeno[1,2-c]pyrazole Analogues as Potential Anticancer Agents Targeting Tubulin Colchicine Binding Site.
    Liu YN, Wang JJ, Ji YT, Zhao GD, Tang LQ, Zhang CM, Guo XL, Liu ZP.
    J Med Chem; 2016 Jun 09; 59(11):5341-55. PubMed ID: 27172319
    [Abstract] [Full Text] [Related]

  • 12. 2-Alkoxycarbonyl-3-arylamino-5-substituted thiophenes as a novel class of antimicrotubule agents: Design, synthesis, cell growth and tubulin polymerization inhibition.
    Romagnoli R, Kimatrai Salvador M, Schiaffino Ortega S, Baraldi PG, Oliva P, Baraldi S, Lopez-Cara LC, Brancale A, Ferla S, Hamel E, Balzarini J, Liekens S, Mattiuzzo E, Basso G, Viola G.
    Eur J Med Chem; 2018 Jan 01; 143():683-698. PubMed ID: 29220790
    [Abstract] [Full Text] [Related]

  • 13. Design, Synthesis, and Evaluation of in Vitro and in Vivo Anticancer Activity of 4-Substituted Coumarins: A Novel Class of Potent Tubulin Polymerization Inhibitors.
    Cao D, Liu Y, Yan W, Wang C, Bai P, Wang T, Tang M, Wang X, Yang Z, Ma B, Ma L, Lei L, Wang F, Xu B, Zhou Y, Yang T, Chen L.
    J Med Chem; 2016 Jun 23; 59(12):5721-39. PubMed ID: 27213819
    [Abstract] [Full Text] [Related]

  • 14. Novel diaryl-2H-azirines: Antitumor hybrids for dual-targeting tubulin and DNA.
    Lin S, Liang Y, Cheng J, Pan F, Wang Y.
    Eur J Med Chem; 2021 Mar 15; 214():113256. PubMed ID: 33581556
    [Abstract] [Full Text] [Related]

  • 15. Synthesis, anticancer activity and molecular docking studies on a series of heterocyclic trans-cyanocombretastatin analogues as antitubulin agents.
    Penthala NR, Zong H, Ketkar A, Madadi NR, Janganati V, Eoff RL, Guzman ML, Crooks PA.
    Eur J Med Chem; 2015 Mar 06; 92():212-20. PubMed ID: 25557492
    [Abstract] [Full Text] [Related]

  • 16. Design, synthesis and antiproliferative activity of the new conjugates of E7010 and resveratrol as tubulin polymerization inhibitors.
    Kamal A, Ashraf M, Basha ST, Ali Hussaini SM, Singh S, Vishnuvardhan MV, Kiran B, Sridhar B.
    Org Biomol Chem; 2016 Jan 28; 14(4):1382-94. PubMed ID: 26676480
    [Abstract] [Full Text] [Related]

  • 17. Design, synthesis of combretastatin A-4 piperazine derivatives as potential antitumor agents by inhibiting tubulin polymerization and inducing autophagy in HCT116 cells.
    Zhang H, Li M, Zhou X, Tang L, Chen G, Zhang Y.
    Eur J Med Chem; 2024 Jun 05; 272():116497. PubMed ID: 38759453
    [Abstract] [Full Text] [Related]

  • 18. Design, synthesis and biological evaluation of a novel tubulin inhibitor 7a3 targeting the colchicine binding site.
    Lai Q, Wang Y, Wang R, Lai W, Tang L, Tao Y, Liu Y, Zhang R, Huang L, Xiang H, Zeng S, Gou L, Chen H, Yao Y, Yang J.
    Eur J Med Chem; 2018 Aug 05; 156():162-179. PubMed ID: 30006162
    [Abstract] [Full Text] [Related]

  • 19. Design, synthesis and antitumor evaluation of novel chiral diaryl substituted azetidin-2-one derivatives as tubulin polymerization inhibitors.
    Liang Y, Zhang M, Zhou P, Liu M, Li J, Wang Y.
    Bioorg Chem; 2021 Oct 05; 115():105239. PubMed ID: 34399321
    [Abstract] [Full Text] [Related]

  • 20. Synthesis and Biochemical Evaluation of 3-Phenoxy-1,4-diarylazetidin-2-ones as Tubulin-Targeting Antitumor Agents.
    Greene TF, Wang S, Greene LM, Nathwani SM, Pollock JK, Malebari AM, McCabe T, Twamley B, O'Boyle NM, Zisterer DM, Meegan MJ.
    J Med Chem; 2016 Jan 14; 59(1):90-113. PubMed ID: 26680364
    [Abstract] [Full Text] [Related]

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