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Journal Abstract Search

79 related items for PubMed ID: 29307731

  • 1. Structural effects of extracellular loop mutations in CFTR helical hairpins.
    Chang YH, Stone TA, Chin S, Glibowicka M, Bear CE, Deber CM.
    Biochim Biophys Acta Biomembr; 2018 May; 1860(5):1092-1098. PubMed ID: 29307731
    [Abstract] [Full Text] [Related]

  • 2. Role of the extracellular loop in the folding of a CFTR transmembrane helical hairpin.
    Wehbi H, Rath A, Glibowicka M, Deber CM.
    Biochemistry; 2007 Jun 19; 46(24):7099-106. PubMed ID: 17516627
    [Abstract] [Full Text] [Related]

  • 3. Positional dependence of non-native polar mutations on folding of CFTR helical hairpins.
    Wehbi H, Gasmi-Seabrook G, Choi MY, Deber CM.
    Biochim Biophys Acta; 2008 Jan 19; 1778(1):79-87. PubMed ID: 17949679
    [Abstract] [Full Text] [Related]

  • 4. CFTR transmembrane segments are impaired in their conformational adaptability by a pathogenic loop mutation and dynamically stabilized by Lumacaftor.
    Krainer G, Schenkel M, Hartmann A, Ravamehr-Lake D, Deber CM, Schlierf M.
    J Biol Chem; 2020 Feb 14; 295(7):1985-1991. PubMed ID: 31882543
    [Abstract] [Full Text] [Related]

  • 5. Structural basis for misfolding at a disease phenotypic position in CFTR: comparison of TM3/4 helix-loop-helix constructs with TM4 peptides.
    Mulvihill CM, Deber CM.
    Biochim Biophys Acta; 2012 Jan 14; 1818(1):49-54. PubMed ID: 21996038
    [Abstract] [Full Text] [Related]

  • 6. Impact of cholesterol and Lumacaftor on the folding of CFTR helical hairpins.
    Schenkel M, Ravamehr-Lake D, Czerniak T, Saenz JP, Krainer G, Schlierf M, Deber CM.
    Biochim Biophys Acta Biomembr; 2023 Jan 01; 1865(1):184078. PubMed ID: 36279907
    [Abstract] [Full Text] [Related]

  • 7. Non-native interhelical hydrogen bonds in the cystic fibrosis transmembrane conductance regulator domain modulated by polar mutations.
    Choi MY, Cardarelli L, Therien AG, Deber CM.
    Biochemistry; 2004 Jun 29; 43(25):8077-83. PubMed ID: 15209503
    [Abstract] [Full Text] [Related]

  • 8. The cystic fibrosis V232D mutation inhibits CFTR maturation by disrupting a hydrophobic pocket rather than formation of aberrant interhelical hydrogen bonds.
    Loo TW, Clarke DM.
    Biochem Pharmacol; 2014 Mar 01; 88(1):46-57. PubMed ID: 24412276
    [Abstract] [Full Text] [Related]

  • 9. Polar residues in membrane domains of proteins: molecular basis for helix-helix association in a mutant CFTR transmembrane segment.
    Partridge AW, Melnyk RA, Deber CM.
    Biochemistry; 2002 Mar 19; 41(11):3647-53. PubMed ID: 11888281
    [Abstract] [Full Text] [Related]

  • 10. Loop sequence dictates the secondary structure of a human membrane protein hairpin.
    Nadeau VG, Deber CM.
    Biochemistry; 2013 Apr 09; 52(14):2419-26. PubMed ID: 23488803
    [Abstract] [Full Text] [Related]

  • 11. Substitution of Yor1p NBD1 residues improves the thermal stability of Human Cystic Fibrosis Transmembrane Conductance Regulator.
    Xavier BM, Hildebrandt E, Jiang F, Ding H, Kappes JC, Urbatsch IL.
    Protein Eng Des Sel; 2017 Oct 01; 30(10):729-741. PubMed ID: 29053845
    [Abstract] [Full Text] [Related]

  • 12. Destabilization of the transmembrane domain induces misfolding in a phenotypic mutant of cystic fibrosis transmembrane conductance regulator.
    Choi MY, Partridge AW, Daniels C, Du K, Lukacs GL, Deber CM.
    J Biol Chem; 2005 Feb 11; 280(6):4968-74. PubMed ID: 15537638
    [Abstract] [Full Text] [Related]

  • 13. Interhelical hydrogen bonds in the CFTR membrane domain.
    Therien AG, Grant FE, Deber CM.
    Nat Struct Biol; 2001 Jul 11; 8(7):597-601. PubMed ID: 11427889
    [Abstract] [Full Text] [Related]

  • 14. Side chain and backbone contributions of Phe508 to CFTR folding.
    Thibodeau PH, Brautigam CA, Machius M, Thomas PJ.
    Nat Struct Mol Biol; 2005 Jan 11; 12(1):10-6. PubMed ID: 15619636
    [Abstract] [Full Text] [Related]

  • 15. Transmembrane domain of cystic fibrosis transmembrane conductance regulator: design, characterization, and secondary structure of synthetic peptides m1-m6.
    Wigley WC, Vijayakumar S, Jones JD, Slaughter C, Thomas PJ.
    Biochemistry; 1998 Jan 20; 37(3):844-53. PubMed ID: 9454574
    [Abstract] [Full Text] [Related]

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  • 17. Sequence hydropathy dominates membrane protein response to detergent solubilization.
    Nadeau VG, Rath A, Deber CM.
    Biochemistry; 2012 Aug 07; 51(31):6228-37. PubMed ID: 22779403
    [Abstract] [Full Text] [Related]

  • 18. Detergent binding explains anomalous SDS-PAGE migration of membrane proteins.
    Rath A, Glibowicka M, Nadeau VG, Chen G, Deber CM.
    Proc Natl Acad Sci U S A; 2009 Feb 10; 106(6):1760-5. PubMed ID: 19181854
    [Abstract] [Full Text] [Related]

  • 19. Cystic fibrosis transmembrane conductance regulator: expression and helicity of a double membrane-spanning segment.
    Peng S, Liu LP, Emili AQ, Deber CM.
    FEBS Lett; 1998 Jul 10; 431(1):29-33. PubMed ID: 9684859
    [Abstract] [Full Text] [Related]

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